TY - GEN
T1 - 3D multi-modal registration for assessing molecular activity changes in time-dependent geometries
AU - Andersson, Madelen
AU - Sakkalis, Vangelis
AU - Ripoll, Jorge
AU - Ntziachristos, Vasilis
AU - Marias, Kostas
PY - 2008
Y1 - 2008
N2 - An important issue for in-vivo fluorescence molecular imaging and tomography has been the robust registration of animals imaged at different time points in order to improve the accuracy of monitoring fluorophore distribution. This paper presents a novel automatic method for aligning 3D temporal data of small animals based on the robust detection of surface anatomical features. Since it is based on 3D surface landmarks the method can be used for mono-modal or multi-modal X-ray CT and/or Optical tomography data in order to account for differences in the positioning and compression of small animals. It can be further extended to other imaging modalities, as well.
AB - An important issue for in-vivo fluorescence molecular imaging and tomography has been the robust registration of animals imaged at different time points in order to improve the accuracy of monitoring fluorophore distribution. This paper presents a novel automatic method for aligning 3D temporal data of small animals based on the robust detection of surface anatomical features. Since it is based on 3D surface landmarks the method can be used for mono-modal or multi-modal X-ray CT and/or Optical tomography data in order to account for differences in the positioning and compression of small animals. It can be further extended to other imaging modalities, as well.
UR - http://www.scopus.com/inward/record.url?scp=61849151396&partnerID=8YFLogxK
U2 - 10.1109/iembs.2008.4650080
DO - 10.1109/iembs.2008.4650080
M3 - Conference contribution
C2 - 19163583
AN - SCOPUS:61849151396
SN - 9781424418152
T3 - Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"
SP - 3975
EP - 3978
BT - Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
PB - IEEE Computer Society
T2 - 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
Y2 - 20 August 2008 through 25 August 2008
ER -