Abstract
A one-pot procedure for the synthesis of 2-fluoro-3-trifluoromethyl- substituted thiophens 6 from 1-aryl-4,4-difluoro-3- trifluoromethylbut-3-en-1-one (3) and phosphorus pentasulfide is described. The fluorine atom at C-2 of compounds 6 undergoes nucleophilic displacement reactions.
Original language | English |
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Pages (from-to) | 13-14 |
Number of pages | 2 |
Journal | Journal of Fluorine Chemistry |
Volume | 66 |
Issue number | 1 |
DOIs | |
State | Published - Jan 1994 |