2D/3D registration of freehand SPECT and planar scintigraphy for clinical evaluation of 3D thyroid scintigraphy

X. Feng, K. Szajkowska, T. Lasser, S. I. Ziegler, N. Navab, T. Wendler

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Thyroid planar scintigraphy is a standard technique in Nuclear Medicine. The clear information it provides it has allowed it to live for decades. Freehand SPECT has been introduced lately as a 3D imaging modality for small anatomies []. In this work, the freehand SPECT technology is applied for the first time for 3D thyroid scintigraphy. A first trial in 10 thyroid patients (40-78y, mean 61) was performed for the purposes of testing and evaluation of this technology in a pilot study setup. For validation a 2D/3D registration method was designed and implemented in order to compared conventional 2D thyroid scintigraphy with the new 3D freehand SPECT images. Further the accuracy of the 2D/3D registration application was evaluated with a synthetic 3D thyroid shape and known rigid transformation. The 2D/3D registration for the synthetic data were bold and the ones of the patient data sets reveal that the freehand SPECT is a promising approach that may open new doors in Nuclear Medicine.

Original languageEnglish
Title of host publicationWorld Congress on Medical Physics and Biomedical Engineering
Subtitle of host publicationDiagnostic Imaging
PublisherSpringer Verlag
Pages737-740
Number of pages4
Edition2
ISBN (Print)9783642038785
DOIs
StatePublished - 2009
EventWorld Congress on Medical Physics and Biomedical Engineering: Diagnostic Imaging - Munich, Germany
Duration: 7 Sep 200912 Sep 2009

Publication series

NameIFMBE Proceedings
Number2
Volume25
ISSN (Print)1680-0737

Conference

ConferenceWorld Congress on Medical Physics and Biomedical Engineering: Diagnostic Imaging
Country/TerritoryGermany
CityMunich
Period7/09/0912/09/09

Keywords

  • 2D/3D registration
  • Gamma probe
  • Image reconstruction
  • Intraoperative imaging
  • Thyroid scintigraphy

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