2.26 MicroRNA as biomaterial

E. R. Balmayor; S. Font Tellado; M. Van Griensven

doi:10.1016/B978-0-12-803581-8.09320-6

2.26 MicroRNA as biomaterial

E. R. Balmayor, S. Font Tellado, M. Van Griensven

Technical University of Munich

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Scopus citations

Abstract

MicroRNA (miRNA) are master regulators of gene expression and impact cell proliferation, differentiation and apoptosis among others. They interact with their target messenger RNA to exert their function. Lately, miRNAs have been associated to many human diseases and their potential as biomarkers and therapeutic has been highlighted. The process of miRNA biogenesis and function is shown. Moreover, miRNA applications in medicine are presented in disease diagnosis or therapeutic use. The latter is presented in detail and illustrated with examples. Special attention is dedicated to the use of biomaterials loaded with miRNAs and their use in tissue engineering and regenerative medicine.

Original language	English
Title of host publication	Comprehensive Biomaterials II
Publisher	Elsevier
Pages	558-570
Number of pages	13
ISBN (Electronic)	9780081006924
ISBN (Print)	9780081006917
DOIs	https://doi.org/10.1016/B978-0-12-803581-8.09320-6
State	Published - 1 Jan 2017
Externally published	Yes

Keywords

Antagomir
Antisense oligonucleotides
Biomaterials
Mimics
Regenerative medicine
Small molecules inhibitors of miRNA
miRNA biogenesis
miRNA cellular function

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/B978-0-12-803581-8.09320-6

Cite this

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abstract = "MicroRNA (miRNA) are master regulators of gene expression and impact cell proliferation, differentiation and apoptosis among others. They interact with their target messenger RNA to exert their function. Lately, miRNAs have been associated to many human diseases and their potential as biomarkers and therapeutic has been highlighted. The process of miRNA biogenesis and function is shown. Moreover, miRNA applications in medicine are presented in disease diagnosis or therapeutic use. The latter is presented in detail and illustrated with examples. Special attention is dedicated to the use of biomaterials loaded with miRNAs and their use in tissue engineering and regenerative medicine.",

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AU - Balmayor, E. R.

AU - Tellado, S. Font

AU - Van Griensven, M.

PY - 2017/1/1

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AB - MicroRNA (miRNA) are master regulators of gene expression and impact cell proliferation, differentiation and apoptosis among others. They interact with their target messenger RNA to exert their function. Lately, miRNAs have been associated to many human diseases and their potential as biomarkers and therapeutic has been highlighted. The process of miRNA biogenesis and function is shown. Moreover, miRNA applications in medicine are presented in disease diagnosis or therapeutic use. The latter is presented in detail and illustrated with examples. Special attention is dedicated to the use of biomaterials loaded with miRNAs and their use in tissue engineering and regenerative medicine.

KW - Antagomir

KW - Antisense oligonucleotides

KW - Biomaterials

KW - Mimics

KW - Regenerative medicine

KW - Small molecules inhibitors of miRNA

KW - miRNA biogenesis

KW - miRNA cellular function

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DO - 10.1016/B978-0-12-803581-8.09320-6

M3 - Chapter

AN - SCOPUS:85076745464

SN - 9780081006917

SP - 558

EP - 570

BT - Comprehensive Biomaterials II

PB - Elsevier

ER -

2.26 MicroRNA as biomaterial

Abstract

Keywords

UN SDGs

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