Research output per year
Research output per year
- 1 - 50 out of 51 results
Search results
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2023
The permanently chaperone-active small heat shock protein Hsp17 from Caenorhabditis elegans exhibits topological separation of its N-terminal regions
Strauch, A., Rossa, B., Köhler, F., Haeussler, S., Mühlhofer, M., Rührnößl, F., Körösy, C., Bushman, Y., Conradt, B., Haslbeck, M., Weinkauf, S. & Buchner, J., Jan 2023, In: Journal of Biological Chemistry. 299, 1, 102753.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
2021
Imbalances in the eye lens proteome are linked to cataract formation
Schmid, P. W. N., Lim, N. C. H., Peters, C., Back, K. C., Bourgeois, B., Pirolt, F., Richter, B., Peschek, J., Puk, O., Amarie, O. V., Dalke, C., Haslbeck, M., Weinkauf, S., Madl, T., Graw, J. & Buchner, J., Feb 2021, In: Nature Structural and Molecular Biology. 28, 2, p. 143-151 9 p.Research output: Contribution to journal › Article › peer-review
33 Scopus citations -
Phosphorylation activates the yeast small heat shock protein Hsp26 by weakening domain contacts in the oligomer ensemble
Mühlhofer, M., Peters, C., Kriehuber, T., Kreuzeder, M., Kazman, P., Rodina, N., Reif, B., Haslbeck, M., Weinkauf, S. & Buchner, J., Dec 2021, In: Nature Communications. 12, 1, 6697.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
2020
Quantifying the insertion of membrane proteins into lipid bilayer nanodiscs using a fusion protein strategy
Häusler, E., Fredriksson, K., Goba, I., Peters, C., Raltchev, K., Sperl, L., Steiner, A., Weinkauf, S. & Hagn, F., 1 Apr 2020, In: Biochimica et Biophysica Acta - Biomembranes. 1862, 4, 183190.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Regulation of small heat-shock proteins by hetero-oligomer formation
Mymrikov, E. V., Riedl, M., Peters, C., Weinkauf, S., Haslbeck, M. & Buchner, J., 3 Jan 2020, In: Journal of Biological Chemistry. 295, 1, p. 158-169 12 p.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
2019
The structure and oxidation of the eye lens chaperone αA-crystallin
Kaiser, C. J. O., Peters, C., Schmid, P. W. N., Stavropoulou, M., Zou, J., Dahiya, V., Mymrikov, E. V., Rockel, B., Asami, S., Haslbeck, M., Rappsilber, J., Reif, B., Zacharias, M., Buchner, J. & Weinkauf, S., 1 Dec 2019, In: Nature Structural and Molecular Biology. 26, 12, p. 1141-1150 10 p.Research output: Contribution to journal › Article › peer-review
Open Access47 Scopus citations -
2016
Structure and function of α-crystallins: Traversing from in vitro to in vivo
Haslbeck, M., Peschek, J., Buchner, J. & Weinkauf, S., Jan 2016, In: Biochimica et Biophysica Acta - General Subjects. 1860, 1, p. 149-166 18 p.Research output: Contribution to journal › Article › peer-review
81 Scopus citations -
2015
The Chaperone Activity of the Developmental Small Heat Shock Protein Sip1 Is Regulated by pH-Dependent Conformational Changes
Fleckenstein, T., Kastenmüller, A., Stein, M. L., Peters, C., Daake, M., Krause, M., Weinfurtner, D., Haslbeck, M., Weinkauf, S., Groll, M. & Buchner, J., 18 Jun 2015, In: Molecular Cell. 58, 6, p. 1067-1078 12 p.Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
The chaperone αb-crystallin uses different interfaces to capture an amorphous and an amyloid client
Mainz, A., Peschek, J., Stavropoulou, M., Back, K. C., Bardiaux, B., Asami, S., Prade, E., Peters, C., Weinkauf, S., Buchner, J. & Reif, B., 4 Nov 2015, In: Nature Structural and Molecular Biology. 22, 11, p. 898-905 8 p.Research output: Contribution to journal › Article › peer-review
Open Access125 Scopus citations -
2014
Leucine-Rich Repeat Kinase 2 Binds to Neuronal Vesicles through Protein Interactions Mediated by Its C-Terminal WD40 Domain
Piccoli, G., Onofri, F., Cirnaru, M. D., Kaiser, C. J. O., Jagtap, P., Kastenmüller, A., Pischedda, F., Marte, A., von Zweydorf, F., Vogt, A., Giesert, F., Pan, L., Antonucci, F., Kiel, C., Zhang, M., Weinkauf, S., Sattler, M., Sala, C., Matteoli, M. & Ueffing, M. & 1 others, , 1 Jun 2014, In: Molecular and Cellular Biology. 34, 12, p. 2147-2161 15 p.Research output: Contribution to journal › Article › peer-review
Open Access87 Scopus citations -
2013
Regulated structural transitions unleash the chaperone actièity of αb-crystallin
Peschek, J., Braun, N., Rohrberg, J., Christiane Back, K., Kriehuber, T., Kastenmüller, A., Weinkauf, S. & Buchner, J., 1 Oct 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 40, p. E3780-E3789Research output: Contribution to journal › Article › peer-review
Open Access140 Scopus citations -
2012
Alternative bacterial two-component small heat shock protein systems
Bepperling, A., Alte, F., Kriehuber, T., Braun, N., Weinkauf, S., Groll, M., Haslbeck, M. & Buchner, J., 11 Dec 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 50, p. 20407-20412 6 p.Research output: Contribution to journal › Article › peer-review
Open Access100 Scopus citations -
2011
Multiple molecular architectures of the eye lens chaperone αB-crystallin elucidated by a triple hybrid approach
Braun, N., Zacharias, M., Peschek, J., Kastenmüller, A., Zou, J., Hanzlik, M., Haslbeck, M., Rappsilber, J., Buchner, J. & Weinkauf, S., 20 Dec 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 51, p. 20491-20496 6 p.Research output: Contribution to journal › Article › peer-review
Open Access130 Scopus citations -
Vibralactone as a tool to study the activity and structure of the ClpP1P2 complex from listeria monocytogenes
Zeiler, E., Braun, N., Böttcher, T., Kastenmüller, A., Weinkauf, S. & Sieber, S. A., 11 Nov 2011, In: Angewandte Chemie International Edition in English. 50, 46, p. 11001-11004 4 p.Research output: Contribution to journal › Article › peer-review
63 Scopus citations -
2010
Hsp12 Is an Intrinsically Unstructured Stress Protein that Folds upon Membrane Association and Modulates Membrane Function
Welker, S., Rudolph, B., Frenzel, E., Hagn, F., Liebisch, G., Schmitz, G., Scheuring, J., Kerth, A., Blume, A., Weinkauf, S., Haslbeck, M., Kessler, H. & Buchner, J., Aug 2010, In: Molecular Cell. 39, 4, p. 507-520 14 p.Research output: Contribution to journal › Article › peer-review
Open Access128 Scopus citations -
2009
Ant antennae: Are they sites for magnetoreception?
De Oliveira, J. F., Wajnberg, E., Esquivel, D. M. D. S., Weinkauf, S., Winklhofer, M. & Hanzlik, M., 1 Jun 2009, In: Journal of the Royal Society Interface. 7, 42, p. 143-152 10 p.Research output: Contribution to journal › Article › peer-review
Open Access55 Scopus citations -
Einzelpartikel-3D-Elektronenmikroskopie: Analyse Heterogener Proteinkomplexe
Translated title of the contribution :Single-particle 3D electron microscopy: Analysis of heterogeneous protein complexes Research output: Contribution to journal › Article › peer-review
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The eye lens chaperone α-crystallin forms defined globular assemblies
Peschek, J., Braun, N., Franzmann, T. M., Georgalis, Y., Haslbeck, M., Weinkauf, S. & Buchner, J., 11 Aug 2009, In: Proceedings of the National Academy of Sciences of the United States of America. 106, 32, p. 13272-13277 6 p.Research output: Contribution to journal › Article › peer-review
Open Access121 Scopus citations -
2008
Improvement of the quality of lumazine synthase crystals by protein engineering
Rodríguez-Fernández, L., López-Jaramillo, F. J., Bacher, A., Fischer, M. & Weinkauf, S., 2008, In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 64, 7, p. 625-628 4 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Structural Dynamics of Archaeal Small Heat Shock Proteins
Haslbeck, M., Kastenmüller, A., Buchner, J., Weinkauf, S. & Braun, N., 25 Apr 2008, In: Journal of Molecular Biology. 378, 2, p. 362-374 13 p.Research output: Contribution to journal › Article › peer-review
56 Scopus citations -
2007
Metastable liquid clusters in super- and undersaturated protein solutions
Gliko, O., Pan, W., Katsonis, P., Neumaier, N., Galkin, O., Weinkauf, S. & Vekilov, P. G., 29 Mar 2007, In: Journal of Physical Chemistry B. 111, 12, p. 3106-3114 9 p.Research output: Contribution to journal › Article › peer-review
107 Scopus citations -
2006
Cloning, purification, crystallization and preliminary crystallographic analysis of SecA from Enterococcus faecalis
Meining, W., Scheuring, J., Fischer, M. & Weinkauf, S., Jun 2006, In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 62, 6, p. 583-585 3 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
The cell-penetrating peptide TAT(48-60) induces a non-lamellar phase in DMPC membranes
Afonin, S., Frey, A., Bayerl, S., Fischer, D., Wadhwani, P., Weinkauf, S. & Ulrich, A. S., 13 Oct 2006, In: ChemPhysChem. 7, 10, p. 2134-2142 9 p.Research output: Contribution to journal › Article › peer-review
70 Scopus citations -
2005
A metastable prerequisite for the growth of lumazine synthase crystals
Gliko, O., Neumaier, N., Pan, W., Haase, I., Fischer, M., Bacher, A., Weinkauf, S. & Vekilov, P. G., 16 Mar 2005, In: Journal of the American Chemical Society. 127, 10, p. 3433-3438 6 p.Research output: Contribution to journal › Article › peer-review
137 Scopus citations -
Determination of liposome size: A tool for protein reconstitution
Vojta, A., Scheuring, J., Neumaier, N., Mirus, O., Weinkauf, S. & Schleiff, E., 1 Dec 2005, In: Analytical Biochemistry. 347, 1, p. 24-33 10 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Influence of particle agglomeration on the catalytic activity of carbon-supported Pt nanoparticles in CO monolayer oxidation
Maillard, F., Schreier, S., Hanzlik, M., Savinova, E. R., Weinkauf, S. & Stimming, U., 2005, In: Physical Chemistry Chemical Physics. p. 375-383 9 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Influence of particle agglomeration on the catalytic activity of carbon-supported Pt nanoparticles in CO monolayer oxidation
Maillard, F., Schreier, S., Hanzlik, M., Savinova, E. R., Weinkauf, S. & Stimming, U., 21 Jan 2005, In: Physical Chemistry Chemical Physics. 7, 2, p. 385-393 9 p.Research output: Contribution to journal › Article › peer-review
390 Scopus citations -
The oligomeric distribution of SecYEG is altered by SecA and translocation ligands
Scheuring, J., Braun, N., Nothdurft, L., Stumpf, M., Veenendaal, A. K. J., Kol, S., Van Der Does, C., Driessen, A. J. M. & Weinkauf, S., 25 Nov 2005, In: Journal of Molecular Biology. 354, 2, p. 258-271 14 p.Research output: Contribution to journal › Article › peer-review
Open Access46 Scopus citations -
2004
Hsp42 is the general small heat shock protein in the cytosol of Saccharomyces cerevisiae
Haslbeck, M., Braun, N., Stromer, T., Richter, B., Model, N., Weinkauf, S. & Buchner, J., 11 Feb 2004, In: EMBO Journal. 23, 3, p. 638-649 12 p.Research output: Contribution to journal › Article › peer-review
Open Access157 Scopus citations -
2002
Formation of metal nanoclusters on specific surface sites of protein molecules
Braun, N., Meining, W., Hars, U., Fischer, M., Ladenstein, R., Huber, R., Bacher, A., Weinkauf, S. & Bachmann, L., 2002, In: Journal of Molecular Biology. 321, 2, p. 341-353 13 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Nucleotide control of interdomain interactions in the conformational reaction cycle of SecA
Hunt, J. F., Weinkauf, S., Henry, L., Fak, J. J., McNicholas, P., Oliver, D. B. & Deisenhofer, J., 20 Sep 2002, In: Science. 297, 5589, p. 2018-2026 9 p.Research output: Contribution to journal › Article › peer-review
243 Scopus citations -
2001
19F NMR ligand perturbation studies on 6,7-bis(trifluoromethyl)-8-ribityllumazine-7-hydrates and the lumazine synthase complex of Bacillus subtilis. Site-directed mutagenesis changes the mechanism and the stereoselectivity of the catalyzed haloform-type reaction
Scheuring, J., Kugelbrey, K., Weinkauf, S., Cushman, M., Bacher, A. & Fischer, M., 1 Jun 2001, In: Journal of Organic Chemistry. 66, 11, p. 3811-3819 9 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
Conformational stabilization and crystallization of the SecA translocation ATPase from Bacillus subtilis
Weinkauf, S., Hunt, J. F., Scheuring, J., Henry, L., Fak, J., Oliver, D. B. & Deisenhofer, J., 2001, In: Acta Crystallographica Section D: Biological Crystallography. 57, 4, p. 559-565 7 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
2000
Electron microscopic observations on protein crystallization: Adsorption layers, aggregates and crystal defects
Braun, N., Tack, J., Fischer, M., Bacher, A., Bachmann, L. & Weinkauf, S., 2000, In: Journal of Crystal Growth. 212, 1, p. 270-282 13 p.Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
Heck reactions catalyzed by oxide-supported palladium - Structure-activity relationships
Wagner, M., Köhler, K., Djakovitch, L., Weinkauf, S., Hagen, V. & Muhler, M., Aug 2000, In: Topics in Catalysis. 13, 3, p. 319-326 8 p.Research output: Contribution to journal › Article › peer-review
106 Scopus citations -
1999
Ultrastructural characterization of peptide-induced membrane fusion and peptide self-assembly in the lipid bilayer
Ulrich, A. S., Tichelaar, W., Förster, G., Zschörnig, O., Weinkauf, S. & Meyer, H. W., Aug 1999, In: Biophysical Journal. 77, 2, p. 829-841 13 p.Research output: Contribution to journal › Article › peer-review
Open Access52 Scopus citations -
1996
Biosynthesis of riboflavin: Structure and mechanism of lumazine synthase
Bacher, A., Fischer, M., Kis, K., Kugelbrey, K., Mortl, S., Scheuring, J., Weinkauf, S., Eberhardt, S., Schmidt-Base, K., Huber, R., Ritsert, K., Cushman, M. & Ladenstein, R., 1996, In: Biochemical Society Transactions. 24, 1, p. 89-94 6 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
Biosynthesis of riboflavin: Lumazine synthase of Escherichia coli
Mörtl, S., Fischer, M., Richter, G., Tack, J., Weinkauf, S. & Bacher, A., 1996, In: Journal of Biological Chemistry. 271, 52, p. 33201-33207 7 p.Research output: Contribution to journal › Article › peer-review
Open Access70 Scopus citations -
Orientation of globular proteins adsorbed on solid substrates: An electron microscopic analysis
Braun, N., Tack, J., Bachmann, L. & Weinkauf, S., 15 Sep 1996, In: Thin Solid Films. 284-285, p. 703-707 5 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Structure and mechanism of GTP cyclohydrolase I of Escherichia coli
Nar, H., Huber, R., Meining, W., Bracher, A., Fischer, M., Hösl, C., Ritz, H., Schmid, C., Weinkauf, S. & Bacher, A., 1996, In: Biochemical Society Transactions. 24, 1, p. 37SResearch output: Contribution to journal › Article › peer-review
5 Scopus citations -
Triazidogallium and derivatives: New precursors to thin films and nanoparticles of GaN
Fischer, R. A., Miehr, A., Herdtweck, E., Mattner, M. R., Ambacher, O., Metzger, T., Born, E., Weinkauf, S., Pulham, C. R. & Parsons, S., 1996, In: Chemistry - A European Journal. 2, 11, p. 1353-1358 6 p.Research output: Contribution to journal › Article › peer-review
68 Scopus citations -
Triazidogallium and derivatives: New precursors to thin films and nanoparticles of GaN
Fischer, R. A., Miehr, A., Herdtweck, E., Mattner, M. R., Ambacher, O., Metzger, T., Born, E., Weinkauf, S., Pulham, C. R. & Parsons, S., 1996, In: Angewandte Chemie International Edition in English. 35, 21, p. 1353-1358 6 p.Research output: Contribution to journal › Article › peer-review
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1995
Atomic structure of GTP cyclohydrolase I
Nar, H., Huber, R., Meining, W., Schmid, C., Weinkauf, S. & Bacher, A., May 1995, In: Structure. 3, 5, p. 459-466 8 p.Research output: Contribution to journal › Article › peer-review
Open Access117 Scopus citations -
Elucidation of Crystal Packing by X-ray Diffraction and Freeze-etching Electron Microscopy. Studies on GTP Cyclohydrolase I ofEscherichia coli
Meining, W., Bacher, A., Bachmann, L., Schmid, C., Weinkauf, S., Huber, R. & Nar, H., 13 Oct 1995, In: Journal of Molecular Biology. 253, 1, p. 208-218 11 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Quantitative evaluation of heavy metal decoration on protein molecules: contrast, specificity and resolution
Rübenkamm, E., Braun, N., Bachmann, L., Bacher, A., Brandt, J., Baumeister, W. & Weinkauf, S., Jun 1995, In: Ultramicroscopy. 58, 3-4, p. 337-351 15 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
1993
Studies on GTP cyclohydrolase I of Escherichia coli
Schmid, C., Meining, W., Weinkauf, S., Bachmann, L., Ritz, H., Eberhardt, S., Gimbel, W., Werner, T., Lahm, H. W., Nar, H. & Bacher, A., 1993, In: Advances in Experimental Medicine and Biology. 338, p. 157-162 6 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
1992
Electron microscopy of decorated crystals for the determination of crystallographic rotation and translation parameters in large protein complexes
Bacher, A., Weinkauf, S., Bachmann, L., Ritsert, K., Baumeister, W., Huber, R. & Ladenstein, R., 20 Jun 1992, In: Journal of Molecular Biology. 225, 4, p. 1065-1073 9 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Metal decoration of biomacromolecules and molecular assemblies: a review
Weinkauf, S. & Bachmann, L., Oct 1992, In: Ultramicroscopy. 46, 1-4, p. 113-134 22 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Subunit stoichiometry three-dimensional arrangement in proteasomes from Thermoplasma acidophilum
Pühler, G., Weinkauf, S., Bachmann, L., M̈ller, S., Engel, A., Hegerl, R. & Baumeister, W., 1992, In: EMBO Journal. 11, 4, p. 1607-1616 10 p.Research output: Contribution to journal › Article › peer-review
174 Scopus citations -
1991
Correlation of metal decoration and topochemistry on protein surfaces
Weinkauf, S., Bacher, A., Baumeister, W., Ladenstein, R., Huber, R. & Bachmann, L., 20 Sep 1991, In: Journal of Molecular Biology. 221, 2, p. 637-645 9 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations