Sapna Sharma

2025

Machine learning approach on plasma proteomics identifies signatures associated with obesity in the KORA FF4 cohort

Niu, J., Adam, J., Skurk, T., Seissler, J., Dong, Q., Efiong, E., Gieger, C., Peters, A., Sharma, S. & Grallert, H., 2025, (Accepted/In press) In: Diabetes, Obesity and Metabolism.

Research output: Contribution to journal › Article › peer-review

2024

Circulatory levels of lysophosphatidylcholine species in obese adolescents: Findings from cross-sectional and prospective lipidomics analyses

Sharma, S., Subrahmanyam, Y. V., Ranjani, H., Sidra, S., Parmar, D., Vadivel, S., Kannan, S., Grallert, H., Usharani, D., Anjana, R. M., Balasubramanyam, M., Mohan, V., Jerzy, A., Panchagnula, V. & Gokulakrishnan, K., Jul 2024, In: Nutrition, Metabolism and Cardiovascular Diseases. 34, 7, p. 1807-1816 10 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Role of human plasma metabolites in prediabetes and type 2 diabetes from the IMI-DIRECT study

Sharma, S., Dong, Q., Haid, M., Adam, J., Bizzotto, R., Fernandez-Tajes, J. J., Jones, A. G., Tura, A., Artati, A., Prehn, C., Kastenmüller, G., Koivula, R. W., Franks, P. W., Walker, M., Forgie, I. M., Giordano, G., Pavo, I., Ruetten, H., Dermitzakis, M. & McCarthy, M. I. & 12 others, Pedersen, O., Schwenk, J. M., Tsirigos, K. D., De Masi, F., Brunak, S., Viñuela, A., Mari, A., McDonald, T. J., Kokkola, T., Adamski, J., Pearson, E. R. & Grallert, H., Dec 2024, In: Diabetologia. 67, 12, p. 2804-2818 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

The Association of Cardiometabolic, Diet and Lifestyle Parameters With Plasma Glucagon-like Peptide-1: An IMI DIRECT Study

Eriksen, R., White, M. C., Dawed, A. Y., Perez, I. G., Posma, J. M., Haid, M., Sharma, S., Prehn, C., Thomas, E. L., Koivula, R. W., Bizzotto, R., Mari, A., Giordano, G. N., Pavo, I., Schwenk, J. M., De Masi, F., Tsirigos, K. D., Brunak, S., Viñuela, A. & Mahajan, A. & 26 others, McDonald, T. J., Kokkola, T., Rutters, F., Beulens, J., Muilwijk, M., Blom, M., Elders, P., Hansen, T. H., Fernandez-Tajes, J., Jones, A., Jennison, C., Walker, M., McCarthy, M. I., Pedersen, O., Ruetten, H., Forgie, I., Holst, J. J., Thomsen, H. S., Ridderstråle, M., Bell, J. D., Adamski, J., Franks, P. W., Hansen, T., Holmes, E., Frost, G. & Pearson, E. R., 1 Sep 2024, In: Journal of Clinical Endocrinology and Metabolism. 109, 9, p. e1697-e1707

Research output: Contribution to journal › Article › peer-review

Open Access

2023

Comparison of gut microbiome profile in patients with schizophrenia and healthy controls - A plausible non-invasive biomarker?

Gokulakrishnan, K., Nikhil, J., Viswanath, B., Thirumoorthy, C., Narasimhan, S., Devarajan, B., Joseph, E., David, A. K. D., Sharma, S., Vasudevan, K., Sreeraj, V. S., Holla, B., Shivakumar, V., Debnath, M., Venkatasubramanian, G. & Varambally, S., Jun 2023, In: Journal of Psychiatric Research. 162, p. 140-149 10 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models

IMI DIRECT Consortium, Mar 2023, In: Nature Biotechnology. 41, 3, p. 399-408 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

48 Scopus citations

Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits

Brown, A. A., Fernandez-Tajes, J. J., Hong, M. G., Brorsson, C. A., Koivula, R. W., Davtian, D., Dupuis, T., Sartori, A., Michalettou, T. D., Forgie, I. M., Adam, J., Allin, K. H., Caiazzo, R., Cederberg, H., De Masi, F., Elders, P. J. M., Giordano, G. N., Haid, M., Hansen, T. & Hansen, T. H. & 134 others, Hattersley, A. T., Heggie, A. J., Howald, C., Jones, A. G., Kokkola, T., Laakso, M., Mahajan, A., Mari, A., McDonald, T. J., McEvoy, D., Mourby, M., Musholt, P. B., Nilsson, B., Pattou, F., Penet, D., Raverdy, V., Ridderstråle, M., Romano, L., Rutters, F., Sharma, S., Teare, H., ‘t Hart, L., Tsirigos, K. D., Vangipurapu, J., Vestergaard, H., Brunak, S., Franks, P. W., Frost, G., Grallert, H., Jablonka, B., McCarthy, M. I., Pavo, I., Pedersen, O., Ruetten, H., Walker, M., Adragni, K., Allesøe, R. L. L., Artati, A. A., Arumugam, M., Atabaki-Pasdar, N., Baltauss, T., Banasik, K., Barnett, A. L., Baum, P., Bell, J. D., Beulens, J. W., Bianzano, S. B., Bizzotto, R., Bonnefond, A., Cabrelli, L., Dale, M., Dawed, A. Y., de Preville, N., Dekkers, K. F., Deshmukh, H. A., Dings, C., Donnelly, L., Dutta, A., Ehrhardt, B., Engelbrechtsen, L., Eriksen, R., Fan, Y., Ferrer, J., Fitipaldi, H., Forman, A., Fritsche, A., Froguel, P., Gassenhuber, J., Gough, S., Graefe-Mody, U., Grempler, R., Groeneveld, L., Groop, L., Gudmundsdóttir, V., Gupta, R., Hennige, A. M. H., Hill, A. V., Holl, R. W., Hudson, M., Jacobsen, U. P., Jennison, C., Johansen, J., Jonsson, A., Karaderi, T., Kaye, J., Kennedy, G., Klintenberg, M., Kuulasmaa, T., Lehr, T., Loftus, H., Lundgaard, A. T. T., Mazzoni, G., McRobert, N., McVittie, I., Nice, R., Nicolay, C., Nijpels, G., Palmer, C. N., Pedersen, H. K., Perry, M. H., Pomares-Millan, H., Prehn, C. P., Ramisch, A., Rasmussen, S., Robertson, N., Rodriquez, M., Sackett, P., Scherer, N., Shah, N., Sihinevich, I., Slieker, R. C., Sondertoft, N. B., Steckel-Hamann, B., Thomas, M. K., Thomas, C. E. E., Thomas, E. L. L., Thorand, B., Thorne, C. E., Tillner, J., Tura, A., Uhlen, M., van Leeuwen, N., van Oort, S., Verkindt, H., Vogt, J., Wad Sackett, P. W., Wesolowska-Andersen, A., Whitcher, B., White, M. W., Adamski, J., Schwenk, J. M., Pearson, E. R., Dermitzakis, E. T. & Viñuela, A., Dec 2023, In: Nature Communications. 14, 1, 5062.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake

The Meta-Analysis of Glucose and Insulin-related Traits Consortium (MAGIC), Jun 2023, In: Nature Genetics. 55, 6, p. 973-983 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

Loci for insulin processing and secretion provide insight into type 2 diabetes risk

Broadaway, K. A., Yin, X., Williamson, A., Parsons, V. A., Wilson, E. P., Moxley, A. H., Vadlamudi, S., Varshney, A., Jackson, A. U., Ahuja, V., Bornstein, S. R., Corbin, L. J., Delgado, G. E., Dwivedi, O. P., Silva, L. F., Frayling, T. M., Grallert, H., Gustafsson, S., Hakaste, L. & Hammar, U. & 51 others, Herder, C., Herrmann, S., Højlund, K., Hughes, D. A., Kleber, M. E., Lindgren, C. M., Liu, C. T., Luan, J., Malmberg, A., Moissl, A. P., Morris, A. P., Perakakis, N., Peters, A., Petrie, J. R., Roden, M., Schwarz, P. E. H., Sharma, S., Silveira, A., Strawbridge, R. J., Tuomi, T., Wood, A. R., Wu, P., Zethelius, B., Baldassarre, D., Eriksson, J. G., Fall, T., Florez, J. C., Fritsche, A., Gigante, B., Hamsten, A., Kajantie, E., Laakso, M., Lahti, J., Lawlor, D. A., Lind, L., März, W., Meigs, J. B., Sundström, J., Timpson, N. J., Wagner, R., Walker, M., Wareham, N. J., Watkins, H., Barroso, I., O'Rahilly, S., Grarup, N., Parker, S. C., Boehnke, M., Langenberg, C., Wheeler, E. & Mohlke, K. L., 2 Feb 2023, In: American Journal of Human Genetics. 110, 2, p. 284-299 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Mapping of the gene network that regulates glycan clock of ageing

Frkatović-Hodžić, A., Mijakovac, A., Miškec, K., Nostaeva, A., Sharapov, S. Z., Landini, A., Haller, T., van den Akker, E., Sharma, S., Cuadrat, R. R. C., Mangino, M., Li, Y., Keser, T., Rudman, N., Štambuk, T., Pučić-Baković, M., Trbojević-Akmačić, I., Gudelj, I., Štambuk, J. & Pribić, T. & 20 others, Radovani, B., Tominac, P., Fischer, K., Beekman, M., Wuhrer, M., Gieger, C., Schulze, M. B., Wittenbecher, C., Polasek, O., Hayward, C., Wilson, J. F., Spector, T. D., Köttgen, A., Vučković, F., Aulchenko, Y. S., Vojta, A., Krištić, J., Klarić, L., Zoldoš, V. & Lauc, G., 2023, In: Aging. 15, 24, p. 14509-14552 44 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Metabolic Signatures Elucidate the Effect of Body Mass Index on Type 2 Diabetes

Dong, Q., Sidra, S., Gieger, C., Wang-Sattler, R., Rathmann, W., Prehn, C., Adamski, J., Koenig, W., Peters, A., Grallert, H. & Sharma, S., Feb 2023, In: Metabolites. 13, 2, 227.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials

DIRECT consortium, Jan 2023, In: The Lancet Diabetes and Endocrinology. 11, 1, p. 33-41 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

40 Scopus citations

2022

Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy

IMPC Consortium & Genomics England Research Consortium, Feb 2022, In: Nature Cardiovascular Research. 1, 2, p. 157-173 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study

IMI DIRECT Consortium, 18 Jan 2022, In: Cell Reports Medicine. 3, 1, 100477.

Research output: Contribution to journal › Article › peer-review

Open Access

58 Scopus citations

2021

Human genome diversity data reveal that L564P is the predominant TPC2 variant and a prerequisite for the blond hair associated M484L gain-of-function effect

Böck, J., Krogsaeter, E., Passon, M., Chao, Y. K., Sharma, S., Grallert, H., Peters, A. & Grimm, C., 19 Jan 2021, In: PLoS Genetics. 17, 1, e1009236.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

Influence of the abiotic stress conditions, waterlogging and drought, on the bitter sensometabolome as well as agronomical traits of six genotypes of daucus carota

Schmid, C., Sharma, S., Stark, T. D., Günzkofer, D., Hofmann, T. F., Ulrich, D., Dunemann, F., Nothnagel, T. & Dawid, C., Jul 2021, In: Foods. 10, 7, 1607.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Revealing the role of the human blood plasma proteome in obesity using genetic drivers

Zaghlool, S. B., Sharma, S., Molnar, M., Matías-García, P. R., Elhadad, M. A., Waldenberger, M., Peters, A., Rathmann, W., Graumann, J., Gieger, C., Grallert, H. & Suhre, K., 1 Dec 2021, In: Nature Communications. 12, 1, 1279.

Research output: Contribution to journal › Article › peer-review

Open Access

52 Scopus citations

2020

A reference map of potential determinants for the human serum metabolome

The IMI DIRECT consortium, 3 Dec 2020, In: Nature. 588, 7836, p. 135-140 6 p.

Research output: Contribution to journal › Article › peer-review

276 Scopus citations

Dietary metabolite profiling brings new insight into the relationship between nutrition and metabolic risk: An IMI DIRECT study

Eriksen, R., Perez, I. G., Posma, J. M., Haid, M., Sharma, S., Prehn, C., Thomas, L. E., Koivula, R. W., Bizzotto, R., Mari, A., Giordano, G. N., Pavo, I., Schwenk, J. M., De Masi, F., Tsirigos, K. D., Brunak, S., Viñuela, A., Mahajan, A., McDonald, T. J. & Kokkola, T. & 17 others, Rutter, F., Teare, H., Hansen, T. H., Fernandez, J., Jones, A., Jennison, C., Walker, M., McCarthy, M. I., Pedersen, O., Ruetten, H., Forgie, I., Bell, J. D., Pearson, E. R., Franks, P. W., Adamski, J., Holmes, E. & Frost, G., Aug 2020, In: eBioMedicine. 58, 102932.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Investigation of adiposity measures and operational taxonomic unit (otu) data transformation procedures in stool samples from a german cohort study using machine learning algorithms

Troll, M., Brandmaier, S., Reitmeier, S., Adam, J., Sharma, S., Sommer, A., Bind, M. A., Neuhaus, K., Clavel, T., Adamski, J., Haller, D., Peters, A. & Grallert, H., Apr 2020, In: Microorganisms. 8, 4, 547.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts

Atabaki-Pasdar, N., Ohlsson, M., Viñuela, A., Frau, F., Pomares-Millan, H., Haid, M., Jones, A. G., Louise Thomas, E., Koivula, R. W., Kurbasic, A., Mutie, P. M., Fitipaldi, H., Fernandez, J., Dawed, A. Y., Giordano, G. N., Forgie, I. M., McDonald, T. J., Rutters, F., Cederberg, H. & Chabanova, E. & 43 others, Dale, M., de Masi, F., Thomas, C. E., Allin, K. H., Hansen, T. H., Heggie, A., Hong, M. G., Elders, P. J. M., Kennedy, G., Kokkola, T., Pedersen, H. K., Mahajan, A., McEvoy, D., Pattou, F., Raverdy, V., Häussler, R. S., Sharma, S., Thomsen, H. S., Vangipurapu, J., Vestergaard, H., T Hart, L. M., Adamski, J., Musholt, P. B., Brage, S., Brunak, S., Dermitzakis, E., Frost, G., Hansen, T., Laakso, M., Pedersen, O., Ridderstråle, M., Ruetten, H., Hattersley, A. T., Walker, M., Beulens, J. W. J., Mari, A., Schwenk, J. M., Gupta, R., McCarthy, M. I., Pearson, E. R., Bell, J. D., Pavo, I. & Franks, P. W., Jun 2020, In: PLoS Medicine. 17, 6, e1003149.

Research output: Contribution to journal › Article › peer-review

Open Access

59 Scopus citations

Whole blood co-expression modules associate with metabolic traits and type 2 diabetes: an IMI-DIRECT study

Gudmundsdottir, V., Pedersen, H. K., Mazzoni, G., Allin, K. H., Artati, A., Beulens, J. W., Banasik, K., Brorsson, C., Cederberg, H., Chabanova, E., De Masi, F., Elders, P. J., Forgie, I., Giordano, G. N., Grallert, H., Gupta, R., Haid, M., Hansen, T., Hansen, T. H. & Hattersley, A. T. & 36 others, Heggie, A., Hong, M. G., Jones, A. G., Koivula, R., Kokkola, T., Laakso, M., Løngreen, P., Mahajan, A., Mari, A., McDonald, T. J., McEvoy, D., Musholt, P. B., Pavo, I., Prehn, C., Ruetten, H., Ridderstråle, M., Rutters, F., Sharma, S., Slieker, R. C., Syed, A., Tajes, J. F., Thomas, C. E., Thomsen, H. S., Vangipurapu, J., Vestergaard, H., Viñuela, A., Wesolowska-Andersen, A., Walker, M., Adamski, J., Schwenk, J. M., McCarthy, M. I., Pearson, E., Dermitzakis, E., Franks, P. W., Pedersen, O. & Brunak, S., Dec 2020, In: Genome Medicine. 12, 1, 109.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

2019

Associations between usual food intake and faecal sterols and bile acids: Results from the Cooperative Health Research in the Augsburg Region (KORA FF4) study

Mitry, P., Wawro, N., Sharma, S., Kriebel, J., Artati, A., Adamski, J., Heier, M., Meisinger, C., Thorand, B., Grallert, H., Peters, A. & Linseisen, J., 14 Aug 2019, In: British Journal of Nutrition. 122, 3, p. 309-321 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration

IMI DIRECT Consortium, 1 Sep 2019, In: Journal of Hepatology. 71, 3, p. 594-602 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

2018

A promiscuous beta-glucosidase is involved in benzoxazinoid deglycosylation in Lamium galeobdolon

Hannemann, L., Lucaciu, C. R., Sharma, S., Rattei, T., Mayer, K. F. X., Gierl, A. & Frey, M., Dec 2018, In: Phytochemistry. 156, p. 224-233 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Identification of genetic elements in metabolism by high-throughput mouse phenotyping

Rozman, J., Rathkolb, B., Oestereicher, M. A., Schütt, C., Ravindranath, A. C., Leuchtenberger, S., Sharma, S., Kistler, M., Willershäuser, M., Brommage, R., Meehan, T. F., Mason, J., Haselimashhadi, H., Aguilar-Pimentel, A., Becker, L., Treise, I., Moreth, K., Garrett, L., Hölter, S. M. & Zimprich, A. & 246 others, Marschall, S., Amarie, O. V., Calzada-Wack, J., Neff, F., Brachthäuser, L., Lengger, C., Stoeger, C., Zapf, L., Cho, Y. L., Da Silva-Buttkus, P., Kraiger, M. J., Mayer-Kuckuk, P., Gampe, K. K., Wu, M., Conte, N., Warren, J., Chen, C. K., Tudose, I., Relac, M., Matthews, P., Cater, H. L., Natukunda, H. P., Cleak, J., Teboul, L. M., Clementson-Mobbs, S., Szoke-Kovacs, Z., Walling, A. P., Johnson, S. J., Codner, G. F., Fiegel, T., Ring, N., Westerberg, H., Greenaway, S., Sneddon, D., Morgan, H., Loeffler, J., Stewart, M. E., Ramirez-Solis, R., Bradley, A., Skarnes, W. C., Steel, K. P., Maguire, S. A., Dench, J., Lafont, D., Vancollie, V. E., Pearson, S. A., Gates, A. S., Sanderson, M., Shannon, C., Anthony, L. F. E., Sumowski, M. T., McLaren, R. S. B., Doe, B., Wardle-Jones, H., Griffiths, M. N. D., Galli, A., Swiatkowska, A., Isherwood, C. M., Speak, A. O., Cambridge, E. L., Wilson, H. M., Caetano, S. S., Maguire, A. K. B., Adams, D. J., Bottomley, J., Ryder, E., Gleeson, D., Pouilly, L., Rousseau, S., Auburtin, A., Reilly, P., Ayadi, A., Selloum, M., Wood, J. A., Clary, D., Havel, P., Tolentino, T., Tolentino, H., Schuchbauer, M., Pedroia, S., Trainor, A., Djan, E., Pham, M., Huynh, A., De Vera, V., Seavitt, J., Gallegos, J., Garza, A., Mangin, E., Senderstrom, J., Lazo, I., Mowrey, K., Bohat, R., Samaco, R., Veeraragavan, S., Beeton, C., Kalaga, S., Kelsey, L., Vukobradovic, I., Berberovic, Z., Owen, C., Qu, D., Guo, R., Newbigging, S., Morikawa, L., Law, N., Shang, X., Feugas, P., Wang, Y., Eskandarian, M., Zhu, Y., Penton, P., Laurin, V., Clarke, S., Lan, Q., Sleep, G., Creighton, A., Jacob, E., Danisment, O., Gertsenstein, M., Pereira, M., MacMaster, S., Tondat, S., Carroll, T., Cabezas, J., Hunter, J., Clark, G., Bubshait, M., Miller, D., Sohel, K., Adissu, H., Ganguly, M., Bezginov, A., Chiani, F., Di Pietro, C., Di Segni, G., Ermakova, O., Ferrara, F., Fruscoloni, P., Gambadoro, A., Gastaldi, S., Golini, E., La Sala, G., Mandillo, S., Marazziti, D., Massimi, M., Matteoni, R., Orsini, T., Pasquini, M., Raspa, M., Rauch, A., Rossi, G., Rossi, N., Putti, S., Scavizzi, F., Tocchini-Valentini, G. D., Wakana, S., Suzuki, T., Tamura, M., Kaneda, H., Furuse, T., Kobayashi, K., Miura, I., Yamada, I., Obata, Y., Yoshiki, A., Ayabe, S., Chambers, J. N., Chalupsky, K., Seisenberger, C., Bürger, A., Beig, J., Kühn, R., Hörlein, A., Schick, J., Oritz, O., Giesert, F., Graw, J., Ollert, M., Schmidt-Weber, C., Stoeger, T., Önder Yildirim, A., Eickelberg, O., Klopstock, T., Busch, D. H., Bekeredjian, R., Zimmer, A., Jacobsen, J. O., Smedley, D., Dickinson, M. E., Benso, F., Morse, I., Kim, H. C., Lee, H., Cho, S. Y., Hough, T., Mallon, A. M., Wells, S., Santos, L., Lelliott, C. J., White, J. K., Sorg, T., Champy, M. F., Bower, L. R., Reynolds, C. L., Flenniken, A. M., Murray, S. A., Nutter, L. M. J., Svenson, K. L., West, D., Tocchini-Valentini, G. P., Beaudet, A. L., Bosch, F., Braun, R. B., Dobbie, M. S., Gao, X., Herault, Y., Moshiri, A., Moore, B. A., Kent Lloyd, K. C., McKerlie, C., Masuya, H., Tanaka, N., Flicek, P., Parkinson, H. E., Sedlacek, R., Seong, J. K., Wang, C. K. L., Moore, M., Brown, S. D., Tschöp, M. H., Wurst, W., Klingenspor, M., Wolf, E., Beckers, J., MacHicao, F., Peter, A., Staiger, H., Häring, H. U., Grallert, H., Campillos, M., Maier, H., Fuchs, H., Gailus-Durner, V., Werner, T. & De Angelis, M. H., 1 Dec 2018, In: Nature Communications. 9, 1, 288.

Research output: Contribution to journal › Article › peer-review

Open Access

57 Scopus citations

IgG glycosylation and DNA methylation are interconnected with smoking

Wahl, A., Kasela, S., Carnero-Montoro, E., van Iterson, M., Štambuk, J., Sharma, S., van den Akker, E., Klaric, L., Benedetti, E., Razdorov, G., Trbojević-Akmačić, I., Vučković, F., Ugrina, I., Beekman, M., Deelen, J., van Heemst, D., Heijmans, B. T., B.I.O.S. Consortium, C., Wuhrer, M. & Plomp, R. & 14 others, Keser, T., Šimurina, M., Pavić, T., Gudelj, I., Krištić, J., Grallert, H., Kunze, S., Peters, A., Bell, J. T., Spector, T. D., Milani, L., Slagboom, P. E., Lauc, G. & Gieger, C., Mar 2018, In: Biochimica et Biophysica Acta - General Subjects. 1862, 3, p. 637-648 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

34 Scopus citations

2017

Genetic variants including markers from the exome chip and metabolite traits of type 2 diabetes

Jäger, S., Wahl, S., Kröger, J., Sharma, S., Hoffmann, P., Floegel, A., Pischon, T., Prehn, C., Adamski, J., Müller-Nurasyid, M., Waldenberger, M., Strauch, K., Peters, A., Gieger, C., Suhre, K., Grallert, H., Boeing, H., Schulze, M. B. & Meidtner, K., 1 Dec 2017, In: Scientific Reports. 7, 1, 6037.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

2015

Comparative transcriptome analysis within the Lolium/Festuca species complex reveals high sequence conservation

Czaban, A., Sharma, S., Byrne, S. L., Spannagl, M., Mayer, K. F. X. & Asp, T., 28 Mar 2015, In: BMC Genomics. 16, 1, 249.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

Joint transcriptomic and metabolomic analyses reveal changes in the primary metabolism and imbalances in the subgenome orchestration in the bread wheat molecular response to Fusarium graminearum

Nussbaumer, T., Warth, B., Sharma, S., Amet, C., Bueschl, C., Parich, A., Pfeifer, M., Siegwart, G., Steiner, B., Lemmens, M., Schuhmacher, R., Buerstmayr, H., Mayer, K. F. X., Kugler, K. G. & Schweiger, W., 2015, In: G3: Genes, Genomes, Genetics. 5, 12, p. 2579-2592 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

37 Scopus citations

2014

A chromosome-based draft sequence of the hexaploid bread wheat (Triticum aestivum) genome

Lukaszewski, A. J., Alberti, A., Sharpe, A., Kilian, A., Stanca, A. M., Keller, B., Clavijo, B. J., Friebe, B., Gill, B., Wulff, B., Chapman, B., Steuernagel, B., Feuillet, C., Viseux, C., Pozniak, C., Rokhsar, D. S., Klassen, D., Edwards, D., Akhunov, E. & Paux, E. & 76 others, Alfama, F., Choulet, F., Kobayashi, F., Muehlbauer, G. J., Quesneville, H., Šimková, H., Rimbert, H., Gundlach, H., Budak, H., Sakai, H., Handa, H., Kanamori, H., Batley, J., Vrána, J., Rogers, J., Číhalíková, J., Doležel, J., Chapman, J., Poland, J. A., Wu, J., Khurana, J., Wright, J., Bader, K. C., Eversole, K., Barry, K., McLay, K., Mayer, K. F. X., Singh, K., Clissold, L., Pingault, L., Couderc, L., Cattivelli, L., Spannagl, M., Kubaláková, M., Caccamo, M., Mascher, M., Bellgard, M., Pfeifer, M., Zytnicki, M., Febrer, M., Alaux, M., Martis, M. M., Loaec, M., Colaiacovo, M., Singh, N. K., Glover, N., Guilhot, N., Stein, N., Olsen, O. A., Maclachlan, P. R., Chhuneja, P., Wincker, P., Sourdille, P., Faccioli, P., Ramirez-Gonzalez, R. H., Waugh, R., Šperková, R., Knox, R., Appels, R., Sharma, S., Ayling, S., Praud, S., Wang, S., Lien, S., Sandve, S. R., Matsumoto, T., Endo, T. R., Itoh, T., Nussbaumer, T., Wicker, T., Tanaka, T., Scholz, U., Barbe, V., Jamilloux, V., Ogihara, Y. & Dubská, Z., 2014, In: Science. 345, 6194, 1251788.

Research output: Contribution to journal › Article › peer-review

1328 Scopus citations

Ancient hybridizations among the ancestral genomes of bread wheat

The International Wheat Genome Sequencing Consortium, 2014, In: Science. 345, 6194, 1250092.

Research output: Contribution to journal › Article › peer-review

538 Scopus citations

Bacteria-triggered systemic immunity in barley is associated with WRKY and ETHYLENE RESPONSIVE FACTORs but not with salicylic acid

Dey, S., Wenig, M., Langen, G., Sharma, S., Kugler, K. G., Knappe, C., Hause, B., Bichlmeier, M., Babaeizad, V., Imani, J., Janzik, I., Stempfl, T., Hückelhoven, R., Kogel, K. H., Mayer, K. F. X. & Corina Vlot, A., 1 Dec 2014, In: Plant Physiology. 166, 4, p. 2133-2151 19 p.

Research output: Contribution to journal › Article › peer-review

Open Access

65 Scopus citations

Genome interplay in the grain transcriptome of hexaploid bread wheat

The International Wheat Genome Sequencing Consortium, 2014, In: Science. 345, 6194

Research output: Contribution to journal › Article › peer-review

Open Access

267 Scopus citations

RNASeqExpressionBrowser-a web interface to browse and visualize high-throughput expression data

Nussbaumer, T., Kugler, K. G., Bader, K. C., Sharma, S., Seidel, M. & Mayer, K. F. X., 1 Sep 2014, In: Bioinformatics. 30, 17, p. 2519-2520 2 p.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

2013

Common genetic polymorphisms modify the effect of smoking on absolute risk of bladder cancer

Garcia-Closas, M., Rothman, N., Figueroa, J. D., Prokunina-Olsson, L., Han, S. S., Baris, D., Jacobs, E. J., Malats, N., De Vivo, I., Albanes, D., Purdue, M. P., Sharma, S., Fu, Y. P., Kogevinas, M., Wang, Z., Tang, W., Tardon, A., Serra, C., Carrato, A. & García-Closas, R. & 24 others, Lloreta, J., Johnson, A., Schwenn, M., Karagas, M. R., Schned, A., Andriole, G., Grubb, R., Black, A., Gapstur, S. M., Thun, M., Diver, W. R., Weinstein, S. J., Virtamo, J., Hunter, D. J., Caporaso, N., Landi, M. T., Hutchinson, A., Burdett, L., Jacobs, K. B., Yeager, M., Fraumeni, J. F., Chanock, S. J., Silverman, D. T. & Chatterjee, N., 1 Apr 2013, In: Cancer Research. 73, 7, p. 2211-2220 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

97 Scopus citations

MIPS PlantsDB: A database framework for comparative plant genome research

Nussbaumer, T., Martis, M. M., Roessner, S. K., Pfeifer, M., Bader, K. C., Sharma, S., Gundlach, H. & Spannagl, M., 1 Jan 2013, In: Nucleic Acids Research. 41, D1, p. D1144-D1151

Research output: Contribution to journal › Article › peer-review

Open Access

143 Scopus citations

Sapna Sharma

Research output

Search results