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Mikael Simons

Prof. Dr.med.

1995 …2025

Research activity per year

Personal profile

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

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Collaborations and top research areas from the last five years

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  • BCAS1-positive oligodendrocytes enable efficient cortical remyelination in multiple sclerosis

    Bergner, C. G., van der Meer, F., Franz, J., Vakrakou, A., Würfel, T., Nessler, S., Schäfer, L., Nau-Gietz, C., Winkler, A., Lagumersindez-Denis, N., Wrzos, C., Damkou, I. A., Sergiou, C., Schultz, V., Knauer, C., Metz, I., Bahn, E., Garea Rodriguez, E., Merkler, D. & Simons, M. & 1 others, Stadelmann, C., 1 Mar 2025, In: Brain. 148, 3, p. 908-920 13 p.

    Research output: Contribution to journal › Article › peer-review

    4 Scopus citations

  • Correction of dysregulated lipid metabolism normalizes gene expression in oligodendrocytes and prolongs lifespan in female poly-GA C9orf72 mice

    Rezaei, A., Kocsis-Jutka, V., Gunes, Z. I., Zeng, Q., Kislinger, G., Bauernschmitt, F., Isilgan, H. B., Parisi, L. R., Kaya, T., Franzenburg, S., Koppenbrink, J., Knogler, J., Arzberger, T., Farny, D., Nuscher, B., Katona, E., Dhingra, A., Yang, C., Gouna, G. & LaClair, K. D. & 10 others, Janjic, A., Enard, W., Zhou, Q., Hagan, N., Ofengeim, D., Beltrán, E., Gokce, O., Simons, M., Liebscher, S. & Edbauer, D., 11 Apr 2025, In: Nature Communications. 16, 1, p. 3442 1 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Erratum: Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology by seeding β-amyloidosis (Immunity (2024) 57(11) (2651–2668.e12), (S1074761324004588), (10.1016/j.immuni.2024.09.014))

    Kaji, S., Berghoff, S. A., Spieth, L., Schlaphoff, L., Sasmita, A. O., Vitale, S., Büschgens, L., Kedia, S., Zirngibl, M., Nazarenko, T., Damkou, A., Hosang, L., Depp, C., Kamp, F., Scholz, P., Ewers, D., Giera, M., Ischebeck, T., Wurst, W. & Wefers, B. & 9 others, Schifferer, M., Willem, M., Nave, K. A., Haass, C., Arzberger, T., Jäkel, S., Wirths, O., Saher, G. & Simons, M., 14 Jan 2025, In: Immunity. 58, 1, p. 263 1 p.

    Research output: Contribution to journal › Comment/debate

    1 Scopus citations

  • Microglia activation orchestrates CXCL10-mediated CD8+ T cell recruitment to promote aging-related white matter degeneration

    Groh, J., Feng, R., Yuan, X., Liu, L., Klein, D., Hutahaean, G., Butz, E., Wang, Z., Steinbrecher, L., Neher, J., Martini, R. & Simons, M., 2025, (Accepted/In press) In: Nature Neuroscience. 1009.

    Research output: Contribution to journal › Article › peer-review

    1 Scopus citations

  • Neuroinflammation in Alzheimer disease

    Heneka, M. T., van der Flier, W. M., Jessen, F., Hoozemanns, J., Thal, D. R., Boche, D., Brosseron, F., Teunissen, C., Zetterberg, H., Jacobs, A. H., Edison, P., Ramirez, A., Cruchaga, C., Lambert, J. C., Laza, A. R., Sanchez-Mut, J. V., Fischer, A., Castro-Gomez, S., Stein, T. D. & Kleineidam, L. & 51 others, Wagner, M., Neher, J. J., Cunningham, C., Singhrao, S. K., Prinz, M., Glass, C. K., Schlachetzki, J. C. M., Butovsky, O., Kleemann, K., De Jaeger, P. L., Scheiblich, H., Brown, G. C., Landreth, G., Moutinho, M., Grutzendler, J., Gomez-Nicola, D., McManus, R. M., Andreasson, K., Ising, C., Karabag, D., Baker, D. J., Liddelow, S. A., Verkhratsky, A., Tansey, M., Monsonego, A., Aigner, L., Dorothée, G., Nave, K. A., Simons, M., Constantin, G., Rosenzweig, N., Pascual, A., Petzold, G. C., Kipnis, J., Venegas, C., Colonna, M., Walter, J., Tenner, A. J., O’Banion, M. K., Steinert, J. R., Feinstein, D. L., Sastre, M., Bhaskar, K., Hong, S., Schafer, D. P., Golde, T., Ransohoff, R. M., Morgan, D., Breitner, J., Mancuso, R. & Riechers, S. P., May 2025, In: Nature Reviews Immunology. 25, 5, p. 321-352 32 p., 170.

    Research output: Contribution to journal › Review article › peer-review

    47 Scopus citations
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