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Mikael Simons

Prof. Dr.med.

1995 …2024

Research activity per year

Personal profile

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

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Collaborations and top research areas from the last five years

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  • Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology by seeding β-amyloidosis

    Kaji, S., Berghoff, S. A., Spieth, L., Schlaphoff, L., Sasmita, A. O., Vitale, S., Büschgens, L., Kedia, S., Zirngibl, M., Nazarenko, T., Damkou, A., Hosang, L., Depp, C., Kamp, F., Scholz, P., Ewers, D., Giera, M., Ischebeck, T., Wurst, W. & Wefers, B. & 9 others, Schifferer, M., Willem, M., Nave, K. A., Haass, C., Arzberger, T., Jäkel, S., Wirths, O., Saher, G. & Simons, M., 2024, (Accepted/In press) In: Immunity.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    5 Scopus citations

  • Erratum: Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology by seeding β-amyloidosis (Immunity (2024) 57(11) (2651–2668.e12), (S1074761324004588), (10.1016/j.immuni.2024.09.014))

    Kaji, S., Berghoff, S. A., Spieth, L., Schlaphoff, L., Sasmita, A. O., Vitale, S., Büschgens, L., Kedia, S., Zirngibl, M., Nazarenko, T., Damkou, A., Hosang, L., Depp, C., Kamp, F., Scholz, P., Ewers, D., Giera, M., Ischebeck, T., Wurst, W. & Wefers, B. & 9 others, Schifferer, M., Willem, M., Nave, K. A., Haass, C., Arzberger, T., Jäkel, S., Wirths, O., Saher, G. & Simons, M., 2024, (Accepted/In press) In: Immunity.

    Research output: Contribution to journal › Comment/debate

  • Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system

    Tiwari, V., Prajapati, B., Asare, Y., Damkou, A., Ji, H., Liu, L., Naser, N., Gouna, G., Leszczyńska, K. B., Mieczkowski, J., Dichgans, M., Wang, Q., Kawaguchi, R., Shi, Z., Swarup, V., Geschwind, D. H., Prinz, M., Gokce, O. & Simons, M., 10 Sep 2024, In: Immunity. 57, 9, p. 2173-2190.e8

    Research output: Contribution to journal › Article › peer-review

    Open Access
    2 Scopus citations

  • Myeloid cell-specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease

    Dinkel, L., Hummel, S., Zenatti, V., Malara, M., Tillmann, Y., Colombo, A., Monasor, L. S., Suh, J. H., Logan, T., Roth, S., Paeger, L., Hoffelner, P., Bludau, O., Schmidt, A., Müller, S. A., Schifferer, M., Nuscher, B., Njavro, J. R., Prestel, M. & Bartos, L. M. & 23 others, Wind-Mark, K., Slemann, L., Hoermann, L., Kunte, S. T., Gnörich, J., Lindner, S., Simons, M., Herms, J., Paquet, D., Lichtenthaler, S. F., Bartenstein, P., Franzmeier, N., Liesz, A., Grosche, A., Bremova-Ertl, T., Catarino, C., Beblo, S., Bergner, C., Schneider, S. A., Strupp, M., Di Paolo, G., Brendel, M. & Tahirovic, S., 4 Dec 2024, In: Science Translational Medicine. 16, 776, p. eadl4616

    Research output: Contribution to journal › Article › peer-review

  • Neuroinflammation in Alzheimer disease

    Heneka, M. T., van der Flier, W. M., Jessen, F., Hoozemanns, J., Thal, D. R., Boche, D., Brosseron, F., Teunissen, C., Zetterberg, H., Jacobs, A. H., Edison, P., Ramirez, A., Cruchaga, C., Lambert, J. C., Laza, A. R., Sanchez-Mut, J. V., Fischer, A., Castro-Gomez, S., Stein, T. D. & Kleineidam, L. & 51 others, Wagner, M., Neher, J. J., Cunningham, C., Singhrao, S. K., Prinz, M., Glass, C. K., Schlachetzki, J. C. M., Butovsky, O., Kleemann, K., De Jaeger, P. L., Scheiblich, H., Brown, G. C., Landreth, G., Moutinho, M., Grutzendler, J., Gomez-Nicola, D., McManus, R. M., Andreasson, K., Ising, C., Karabag, D., Baker, D. J., Liddelow, S. A., Verkhratsky, A., Tansey, M., Monsonego, A., Aigner, L., Dorothée, G., Nave, K. A., Simons, M., Constantin, G., Rosenzweig, N., Pascual, A., Petzold, G. C., Kipnis, J., Venegas, C., Colonna, M., Walter, J., Tenner, A. J., O’Banion, M. K., Steinert, J. R., Feinstein, D. L., Sastre, M., Bhaskar, K., Hong, S., Schafer, D. P., Golde, T., Ransohoff, R. M., Morgan, D., Breitner, J., Mancuso, R. & Riechers, S. P., 2024, (Accepted/In press) In: Nature Reviews Immunology. 170.

    Research output: Contribution to journal › Review article › peer-review

View all 165 Research outputs