Matthias Tschöp

Dr.

1997 …2025

Research activity per year

Personal profile

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 2 - Zero Hunger
  • SDG 3 - Good Health and Well-being

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Collaborations and top research areas from the last five years

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  • A once-daily GLP-1/GIP/glucagon receptor tri-agonist (NN1706) lowers body weight in rodents, monkeys and humans

    Finan, B., Douros, J. D., Goldwater, R., Hansen, A. M. K., Hjerpsted, J. B., Hjøllund, K. R., Kankam, M. K., Knerr, P. J., Konkar, A., Mowery, S. A., Müller, T. D., Nielsen, J. R., Nygård, S. B., Perez-Tilve, D., Raun, K., Yang, B., Tschöp, M. H. & DiMarchi, R. D., Jun 2025, In: Molecular Metabolism. 96, 102129.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Definition and diagnostic criteria of clinical obesity

    Rubino, F., Cummings, D. E., Eckel, R. H., Cohen, R. V., Wilding, J. P. H., Brown, W. A., Stanford, F. C., Batterham, R. L., Farooqi, I. S., Farpour-Lambert, N. J., le Roux, C. W., Sattar, N., Baur, L. A., Morrison, K. M., Misra, A., Kadowaki, T., Tham, K. W., Sumithran, P., Garvey, W. T. & Kirwan, J. P. & 36 others, Fernández-Real, J. M., Corkey, B. E., Toplak, H., Kokkinos, A., Kushner, R. F., Branca, F., Valabhji, J., Blüher, M., Bornstein, S. R., Grill, H. J., Ravussin, E., Gregg, E., Al Busaidi, N. B., Alfaris, N. F., Al Ozairi, E., Carlsson, L. M. S., Clément, K., Després, J. P., Dixon, J. B., Galea, G., Kaplan, L. M., Laferrère, B., Laville, M., Lim, S., Luna Fuentes, J. R., Mooney, V. M., Nadglowski, J., Urudinachi, A., Olszanecka-Glinianowicz, M., Pan, A., Pattou, F., Schauer, P. R., Tschöp, M. H., van der Merwe, M. T., Vettor, R. & Mingrone, G., Mar 2025, In: The Lancet Diabetes and Endocrinology. 13, 3, p. 221-262 42 p.

    Research output: Contribution to journalReview articlepeer-review

    149 Scopus citations
  • Estrogenic activity of E2-conjugated GLP-1 is mediated by intracellular endolysosomal acidification and estrone metabolism

    Coupland, C., Sun, N., Khalil, A., Karaoglu, Ö. E., Liskiewicz, A., Liskiewicz, D., Grandl, G., Akindehin, S., Maity, G., Yang, B., Finan, B., Knerr, P., Douros, J. D., Walch, A., DiMarchi, R., Tschöp, M. H., Müller, T. D. & Novikoff, A., Jun 2025, In: Molecular Metabolism. 96, 102136.

    Research output: Contribution to journalArticlepeer-review

  • GIPR agonism and antagonism decrease body weight and food intake via different mechanisms in male mice

    Gutgesell, R. M., Khalil, A., Liskiewicz, A., Maity-Kumar, G., Novikoff, A., Grandl, G., Liskiewicz, D., Coupland, C., Karaoglu, E., Akindehin, S., Castelino, R., Curion, F., Liu, X., Garcia-Caceres, C., Cebrian-Serrano, A., Douros, J. D., Knerr, P. J., Finan, B., DiMarchi, R. D. & Sloop, K. W. & 4 others, Samms, R. J., Theis, F. J., Tschöp, M. H. & Müller, T. D., 2025, (Accepted/In press) In: Nature Metabolism. 4981.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Glucose-dependent insulinotropic polypeptide (GIP)

    Müller, T. D., Adriaenssens, A., Ahrén, B., Blüher, M., Birkenfeld, A. L., Campbell, J. E., Coghlan, M. P., D'Alessio, D., Deacon, C. F., DelPrato, S., Douros, J. D., Drucker, D. J., Figueredo Burgos, N. S., Flatt, P. R., Finan, B., Gimeno, R. E., Gribble, F. M., Hayes, M. R., Hölscher, C. & Holst, J. J. & 19 others, Knerr, P. J., Knop, F. K., Kusminski, C. M., Liskiewicz, A., Mabilleau, G., Mowery, S. A., Nauck, M. A., Novikoff, A., Reimann, F., Roberts, A. G., Rosenkilde, M. M., Samms, R. J., Scherer, P. E., Seeley, R. J., Sloop, K. W., Wolfrum, C., Wootten, D., DiMarchi, R. D. & Tschöp, M. H., May 2025, In: Molecular Metabolism. 95, 102118.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    3 Scopus citations