Research output per year
Research output per year
- 1 - 50 out of 384 results
Search results
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2025
Early total care and damage control orthopaedics result in partially contrasting patterns of microRNA expression at the fracture site and in the systemic circulation
Groven, R. V. M., Mert, Greven, J., Horst, K., Joris, V., Bini, L., Poeze, M., Blokhuis, T. J., Huber-Lang, M., Hildebrand, F. & van Griensven, M., Feb 2025, In: Bone and Joint Journal. 107 B, 2, p. 193-203 11 p.Research output: Contribution to journal › Article › peer-review
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Implementing BMP-7 Chemically Modified RNA for Bone Regeneration with 3D Printable Hyaluronic Acid-Collagen Granular Gels
van der Heide, D., del Toro Runzer, C., Della Bella, E., Plank, C., van Griensven, M., Balmayor, E. R., Stoddart, M. J. & D'Este, M., 2025, (Accepted/In press) In: Advanced Healthcare Materials.Research output: Contribution to journal › Article › peer-review
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Inside the cell: Approaches to evaluating mRNA internalization and trafficking
Del Toro Runzer, C., Plank, C., van Griensven, M. & Balmayor, E. R., Sep 2025, In: Methods. 241, p. 173-183 11 p.Research output: Contribution to journal › Article › peer-review
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miR-125b differentially impacts mineralization in dexamethasone and calcium-treated human mesenchymal stem cells
Joris, V., Balmayor, E. R. & van Griensven, M., 11 Mar 2025, In: Molecular Therapy - Nucleic Acids. 36, 1, 102446.Research output: Contribution to journal › Article › peer-review
Open Access -
2024
A ROADMAP OF OSTEOGENIC DIFFERENTIATION IN HUMAN MESENCHYMAL STEM CELLS ASSESSED BY PROTEIN MULTIPLEX ANALYSIS
Eischen-Loges, M., Tahmasebi Birgani, Z., Alaoui Selsouli, Y., Eijssen, L., Rho, H., Sthijns, M., van Griensven, M., Lapointe, V. & Habibović, P., 1 Jan 2024, In: European Cells and Materials. 47, p. 170-189 20 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Damage Control Orthopaedics Induced Less Trauma-Induced Coagulopathy than Early Total Care in a Porcine Polytrauma Model
Mert, Ü., Groven, R. V. M., Greven, J., He, Z., Mahmoud, M. A., Van Griensven, M., Huber-Lang, M., Mollnes, T. E., Rosado Balmayor, E., Horst, K. & Hildebrand, F., 30 Sep 2024, In: European Surgical Research. 65, 1, p. 115-122 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Enthesitis on Chip – A Model for Studying Acute and Chronic Inflammation of the Enthesis and its Pharmacological Treatment
Giacomini, F., Rho, H. S., Eischen-Loges, M., Tahmasebi Birgani, Z., van Blitterswijk, C., van Griensven, M., Giselbrecht, S., Habibović, P. & Truckenmüller, R., 16 Dec 2024, In: Advanced Healthcare Materials. 13, 31, 2401815.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Extracellular vesicles are key players in mesenchymal stem cells’ dual potential to regenerate and modulate the immune system
van Griensven, M. & Balmayor, E. R., Apr 2024, In: Advanced Drug Delivery Reviews. 207, 115203.Research output: Contribution to journal › Review article › peer-review
Open Access16 Scopus citations -
Fracture haematoma proteomics
Groven, R. V. M., Kuik, C., Greven, J., Mert, Bouwman, F. G., Poeze, M., Blokhuis, T. J., Huber-Lang, M., Hildebrand, F., Cillero-Pastor, B. & van Griensven, M., May 2024, In: Bone and Joint Research. 13, 5, p. 214-225 12 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Is there a role for N1-N2 neutrophil phenotypes in bone regeneration? A systematic review
Lu, F., Verleg, S. M. N. E., Groven, R. V. M., Poeze, M., van Griensven, M. & Blokhuis, T. J., Apr 2024, In: Bone. 181, 117021.Research output: Contribution to journal › Review article › peer-review
Open Access7 Scopus citations -
Mini-bones: miniaturized bone in vitro models
Fois, M. G., van Griensven, M., Giselbrecht, S., Habibović, P., Truckenmüller, R. K. & Tahmasebi Birgani, Z. N., Jul 2024, In: Trends in Biotechnology. 42, 7, p. 910-928 19 p.Research output: Contribution to journal › Review article › peer-review
Open Access5 Scopus citations -
Modulation of the hepatic RANK-RANKL-OPG axis by combined C5 and CD14 inhibition in a long-term polytrauma model
Li, Y., Horst, K., Greven, J., Mert, Ü., Lupu, L., Palmer, A., Doerfer, L., Zhao, Q., Zhang, X., Halbgebauer, R., Ignatius, A., Marzi, I., van Griensven, M., Balmayor, E., Hildebrand, F., Mollnes, T. E. & Huber-Lang, M., 2024, In: Frontiers in Immunology. 15, 1434274.Research output: Contribution to journal › Article › peer-review
Open Access -
Neuromuscular electrical stimulation to combat cognitive aging in people with spinal cord injury: protocol for a single case experimental design study
Vints, W. A. J., Levin, O., van Griensven, M., Vlaeyen, J. W. S., Masiulis, N., Verbunt, J. & van Laake-Geelen, C. C. M., Dec 2024, In: BMC Neurology. 24, 1, 197.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Polytherapy versus monotherapy in the treatment of tibial non-unions: a retrospective study
Lu, F., Groven, R. V. M., van Griensven, M., Poeze, M., Geurts, J. A. P., Qiu, S. S. & Blokhuis, T. J., Dec 2024, In: Journal of Orthopaedics and Traumatology. 25, 1, 21.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Pulmonary miRNA expression after polytrauma depends on the surgical invasiveness and displays an anti-inflammatory pattern by the combined inhibition of C5 and CD14
Zhou, N., Groven, R. V. M., Horst, K., Mert, Ü., Greven, J., Mollnes, T. E., Huber-Lang, M., van Griensven, M., Hildebrand, F. & Balmayor, E. R., 2024, In: Frontiers in Immunology. 15, 1402571.Research output: Contribution to journal › Article › peer-review
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Reprogramming tendon healing: a guide to novel molecular tools
Peniche Silva, C. J., Balmayor, E. R. & van Griensven, M., 2024, In: Frontiers in Bioengineering and Biotechnology. 12, 1379773.Research output: Contribution to journal › Review article › peer-review
Open Access3 Scopus citations -
Surgical suction filter-derived bone graft displays osteogenic miRNA and mRNA patterns
Groven, R. V. M., Blokhuis, J. T., Poeze, M., van Griensven, M. & Blokhuis, T. J., Feb 2024, In: European Journal of Trauma and Emergency Surgery. 50, 1, p. 315-326 12 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
2023
Cellular uptake of modified mRNA occurs via caveolae-mediated endocytosis, yielding high protein expression in slow-dividing cells
Del Toro Runzer, C., Anand, S., Mota, C., Moroni, L., Plank, C., van Griensven, M. & Balmayor, E. R., 13 Jun 2023, In: Molecular Therapy - Nucleic Acids. 32, p. 960-979 20 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Circulating miRNA expression in extracellular vesicles is associated with specific injuries after multiple trauma and surgical invasiveness
Groven, R. V. M., Greven, J., Mert, Ü., Horst, K., Zhao, Q., Blokhuis, T. J., Huber-Lang, M., Hildebrand, F. & van Griensven, M., 2023, In: Frontiers in Immunology. 14, 1273612.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Computational evidence for multi-layer crosstalk between the cadherin-11 and PDGFR pathways
Karagöz, Z., Passanha, F. R., Robeerst, L., van Griensven, M., LaPointe, V. L. S. & Carlier, A., Dec 2023, In: Scientific Reports. 13, 1, 15804.Research output: Contribution to journal › Article › peer-review
Open Access -
Editorial: Insights in tissue engineering and regenerative medicine 2021: Novel developments, current challenges, and future perspectives
Cancedda, R., Murphy, J. M. & Van Griensven, M., 12 Jan 2023, In: Frontiers in Bioengineering and Biotechnology. 10, 1125027.Research output: Contribution to journal › Editorial
Open Access5 Scopus citations -
Editorial: Immune response to SARS-CoV-2 and implications for clinical outcome
Bölke, E., van Griensven, M., Schneider, E. M., Fischer, J. C., Feldt, T., Keitel, V., Budach, W., Haussmann, J., Jazmati, D. & Matuschek, C., 2023, In: Frontiers in Immunology. 14, 1233291.Research output: Contribution to journal › Editorial
Open Access -
Isolation of adipose derived mesenchymal stem cells by using anti-CD105 VHH-magnetic beads
Gushiken, E., Quintana, M., Perez, L. A., Herrera-Velit, P., Balmayor, E. R., van Griensven, M. & Espinoza, J. R., Nov 2023, In: Electronic Journal of Biotechnology. 66, p. 60-66 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Liquid Biopsy in Organ Damage: small extracellular vesicle chip-based assessment of polytrauma
Wang, B., Wöhler, A., Greven, J., Salzmann, R. J. S., Keller, C. M., Tertel, T., Zhao, Q., Mert, Ü., Horst, K., Lupu, L., Huber-Lang, M., van Griensven, M., Mollnes, T. E., Schaaf, S., Schwab, R., Strassburg, C. P., Schmidt-Wolf, I. G. H., Giebel, B., Hildebrand, F. & Lukacs-Kornek, V. & 2 others, , 2023, In: Frontiers in Immunology. 14, 1279496.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
MiRNAs as Potential Regulators of Enthesis Healing: Findings in a Rodent Injury Model
Peniche Silva, C. J., De La Vega, R. E., Panos, J., Joris, V., Evans, C. H., Balmayor, E. R. & van Griensven, M., May 2023, In: International Journal of Molecular Sciences. 24, 10, 8556.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Percutaneous fractionated radiotherapy of the groin to eliminate lymphatic fistulas after vascular surgery
Jazmati, D., Tamaskovics, B., Hoff, N. P., Homey, B., Bölke, E., Boyomo, B., Garabet, W., Haussmann, J., Budach, W., Neuwahl, J., Schelzig, H., Corradini, S., van Griensven, M., Fischer, J., Knoefel, W. T., Pegani, J., Pedoto, A., Antoch, G., Kirchner, J. & Lüdde, T. & 5 others, , Dec 2023, In: European Journal of Medical Research. 28, 1, 70.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Silk biomaterials for tendon and tendon-to-bone enthesis tissue engineering
Peniche Silva, C. J., Rosado Balmayor, E. & van Griensven, M., 1 Jan 2023, Silk-Based Biomaterials for Tissue Engineering, Regenerative, and Precision Medicine, 2nd Edition. Elsevier, p. 549-565 17 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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2022
Acute cardiac side effects after COVID-19 mRNA vaccination: a case series
Freise, N. F., Kivel, M., Grebe, O., Meyer, C., Wafaisade, B., Peiper, M., Zeus, T., Schmidt, J., Neuwahl, J., Jazmati, D., Luedde, T., Bölke, E., Feldt, T., Jensen, B. E. O., Bode, J., Keitel, V., Haussmann, J., Tamaskovics, B., Budach, W. & Fischer, J. C. & 12 others, , Dec 2022, In: European Journal of Medical Research. 27, 1, 80.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
A Microwell-Based Intestinal Organoid-Macrophage Co-Culture System to Study Intestinal Inflammation
Kakni, P., Truckenmüller, R., Habibović, P., van Griensven, M. & Giselbrecht, S., Dec 2022, In: International Journal of Molecular Sciences. 23, 23, 15364.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Dysregulation of Wnt signaling in bone of type 2 diabetes mellitus and diabetic Charcot arthropathy
Gassel, L. C., Schneider, S., Banke, I. J., Braun, K. F., Volkering, C., Zeeb, L., Burgkart, R. H. H., von Eisenhart-Rothe, R., Biberthaler, P., van Griensven, M. & Haug, A. T., Dec 2022, In: BMC Musculoskeletal Disorders. 23, 1, 365.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Editorial overview: Tissue, cell, and pathway engineering
Moroni, L. & van Griensven, M., Oct 2022, In: Current Opinion in Biotechnology. 77, 102758.Research output: Contribution to journal › Editorial
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Efficient healing of large osseous segmental defects using optimized chemically modified messenger RNA encoding BMP-2
de la Vega, R. E., van Griensven, M., Zhang, W., Coenen, M. J., Nagelli, C. V., Panos, J. A., Peniche Silva, C. J., Geiger, J., Plank, C., Evans, C. H. & Balmayor, E. R., Feb 2022, In: Science Advances. 8, 7, eabl6242.Research output: Contribution to journal › Article › peer-review
Open Access45 Scopus citations -
Enhanced Microvasculature Formation and Patterning in iPSC–Derived Kidney Organoids Cultured in Physiological Hypoxia
Schumacher, A., Roumans, N., Rademakers, T., Joris, V., Eischen-Loges, M. J., van Griensven, M. & LaPointe, V. L. S., 13 Jun 2022, In: Frontiers in Bioengineering and Biotechnology. 10, 860138.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
ENTHESIS: NOT THE SAME IN EACH LOCALISATION – A MOLECULAR, HISTOLOGICAL AND BIOMECHANICAL STUDY
Peniche Silva, C. J., Müller, S. A., Quirk, N., De la Vega, R. E., Coenen, M. J., Evans, C. H., Balmayor, E. R. & van Griensven, M., 1 Jul 2022, In: European Cells and Materials. 44, p. 43-55 13 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Enthesis Healing Is Dependent on Scaffold Interphase Morphology—Results from a Rodent Patellar Model
Peniche Silva, C. J., Müller, S. A., Quirk, N., Poh, P. S. P., Mayer, C., Motta, A., Migliaresi, C., Coenen, M. J., Evans, C. H., Balmayor, E. R. & van Griensven, M., 1 Jun 2022, In: Cells. 11, 11, 1752.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Lipid Analysis of Fracture Hematoma With MALDI-MSI: Specific Lipids are Associated to Bone Fracture Healing Over Time
Groven, R. V. M., Nauta, S. P., Gruisen, J., Claes, B. S. R., Greven, J., van Griensven, M., Poeze, M., Heeren, R. M. A., Porta Siegel, T., Cillero-Pastor, B. & Blokhuis, T. J., 3 Mar 2022, In: Frontiers in Chemistry. 9, 780626.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Low-dose radiation treatment for painful plantar enthesophyte: a highly effective therapy with little side effects
Djiepmo, F., Tamaskovics, B., Bölke, E., Peiper, M., Haussmann, J., Neuwahl, J., Jazmati, D., Maas, K., Schmidt, L., Gelzhäuser, R., Schleich, C., Corradini, S., Orth, K., van Griensven, M., Rezazadeh, A., Karimi, K., Budach, W. & Matuschek, C., Dec 2022, In: European Journal of Medical Research. 27, 1, 28.Research output: Contribution to journal › Article › peer-review
Open Access -
MECHANICAL AND STRAIN BEHAVIOUR OF HUMAN ACHILLES TENDON DURING IN VITRO TESTING TO FAILURE
Nagelli, C. V., Hooke, A., Quirk, N., De Padilla, C. L., Hewett, T. E., van Griensven, M., Coenen, M., Berglund, L., Evans, C. H. & Müller, S. A., 1 Jan 2022, In: European Cells and Materials. 43, p. 153-161 9 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Pathophysiology: Remote Organ Injury
van Griensven, M., 1 Jan 2022, Textbook of Polytrauma Management: a Multidisciplinary Approach, Third Edition. Springer International Publishing, p. 127-134 8 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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Prognostic markers for the clinical course in the blood of patients with SARS-CoV-2 infection
Fischer, J. C., Balz, V., Jazmati, D., Bölke, E., Freise, N. F., Keitel, V., Feldt, T., Jensen, B. E. O., Bode, J., Lüdde, T., Häussinger, D., Adams, O., Schneider, E. M., Enczmann, J., Rox, J. M., Hermsen, D., Schulze-Bosse, K., Kindgen-Milles, D., Knoefel, W. T. & van Griensven, M. & 22 others, , Dec 2022, In: European Journal of Medical Research. 27, 1, 255.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Simultaneous C5 and CD14 inhibition limits inflammation and organ dysfunction in pig polytrauma
Lupu, L., Horst, K., Greven, J., Mert, Ü., Ludviksen, J. A. K., Pettersen, K., Lau, C., Li, Y., Palmer, A., Qin, K., Zhang, X., Mayer, B., van Griensven, M., Huber-Lang, M., Hildebrand, F. & Mollnes, T. E., 2022, In: Frontiers in Immunology. 13, p. 952267 1 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Specific microRNAs are associated with fracture healing phases, patient age and multi-trauma
Groven, R. V. M., Peniche Silva, C. J., Balmayor, E. R., van der Horst, B. N. J., Poeze, M., Blokhuis, T. J. & van Griensven, M., Nov 2022, In: Journal of Orthopaedic Translation. 37, p. 1-11 11 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Standardized porcine unilateral femoral nailing is associated with changes in PMN activation status, rather than aberrant systemic PMN prevalence
TREAT-Research Collaboration, Jun 2022, In: European Journal of Trauma and Emergency Surgery. 48, 3, p. 1601-1611 11 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
2021
A Graded, Porous Composite of Natural Biopolymers and Octacalcium Phosphate Guides Osteochondral Differentiation of Stem Cells
Amann, E., Amirall, A., Franco, A. R., Poh, P. S. P., Sola Dueñas, F. J., Fuentes Estévez, G., Leonor, I. B., Reis, R. L., van Griensven, M. & Balmayor, E. R., 17 Mar 2021, In: Advanced Healthcare Materials. 10, 6, 2001692.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
Application of a Hyperelastic 3D Printed Scaffold for Mesenchymal Stem Cell-Based Fabrication of a Bizonal Tendon Enthesis-like Construct
Gottardi, R., Moeller, K., Di Gesù, R., Tuan, R. S., van Griensven, M. & Balmayor, E. R., 8 Mar 2021, In: Frontiers in Materials. 8, 613212.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Association of HLA genotypes, AB0 blood type and chemokine receptor 5 mutant CD195 with the clinical course of COVID-19
Fischer, J. C., Schmidt, A. G., Bölke, E., Uhrberg, M., Keitel, V., Feldt, T., Jensen, B., Häussinger, D., Adams, O., Schneider, E. M., Balz, V., Enczmann, J., Rox, J., Hermsen, D., Schulze-Bosse, K., Kindgen-Milles, D., Knoefel, W. T., van Griensven, M., Haussmann, J. & Tamaskovics, B. & 19 others, , Dec 2021, In: European Journal of Medical Research. 26, 1, 107.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Corrigendum: Win, Lose or Tie: Mathematical Modeling of Ligand Competition at the Cell-Extracellular Matrix Interface (Front. Bioeng. Biotechnol, (2021), 9, (657244), 10.3389/fbioe.2021.657244)
Karagöz, Z., Geuens, T., LaPointe, V. L. S., van Griensven, M. & Carlier, A., 22 Sep 2021, In: Frontiers in Bioengineering and Biotechnology. 9, 771429.Research output: Contribution to journal › Comment/debate
Open Access1 Scopus citations -
Defining the variety of cell types in developing and adult human kidneys by single-cell RNA sequencing
Schumacher, A., Rookmaaker, M. B., Joles, J. A., Kramann, R., Nguyen, T. Q., van Griensven, M. & LaPointe, V. L. S., Dec 2021, In: npj Regenerative Medicine. 6, 1, 45.Research output: Contribution to journal › Review article › peer-review
Open Access37 Scopus citations -
Delayed skin reaction after mRNA-1273 vaccine against SARS-CoV-2: a rare clinical reaction
Hoff, N. P., Freise, N. F., Schmidt, A. G., Firouzi-Memarpuri, P., Reifenberger, J., Luedde, T., Bölke, E., Meller, S., Homey, B., Feldt, T., Jensen, B. E. O., Keitel, V., Schmidt, L., Maas, K., Haussmann, J., Tamaskovics, B., Budach, W., Fischer, J. C., Buhren, B. A. & Knoefel, W. T. & 10 others, , Dec 2021, In: European Journal of Medical Research. 26, 1, 98.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Direct comparison of 3D and 2D cultivation reveals higher osteogenic capacity of elderly osteoblasts in 3D
Payr, S., Rosado-Balmayor, E., Tiefenboeck, T., Schuseil, T., Unger, M., Seeliger, C. & van Griensven, M., Dec 2021, In: Journal of Orthopaedic Surgery and Research. 16, 1, 13.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations