Heinz Höfler

2019

High proliferation rate and TNM stage but not histomorphological subtype are independent prognostic markers for overall survival in papillary renal cell carcinoma

German Network Of Kidney Cancer, Jan 2019, In: Human Pathology. 83, p. 212-223 12 p.

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

2017

Decision impact and feasibility of different ASCO-recommended biomarkers in early breast cancer: Prospective comparison of molecular marker EndoPredict and protein marker uPA/PAI-1

Ettl, J., Klein, E., Hapfelmeier, A., Grosse Lackmann, K., Paepke, S., Petry, C., Specht, K., Wolff, L., Höfler, H. & Kiechle, M., Sep 2017, In: PLoS ONE. 12, 9, e0183917.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

2015

Additive impact of HER2-/PTK6-RNAi on interactions with HER3 or IGF-1R leads to reduced breast cancer progression in vivo

Falkenberg, N., Anastasov, N., Höfig, I., Bashkueva, K., Lindner, K., Höfler, H., Rosemann, M. & Aubele, M., 1 Jan 2015, In: Molecular Oncology. 9, 1, p. 282-294 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics

EUMODIC Consortium, 27 Aug 2015, In: Nature Genetics. 47, 9, p. 969-978 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

124 Scopus citations

De novo discovery of phenotypic intratumour heterogeneity using imaging mass spectrometry

Balluff, B., Frese, C. K., Maier, S. K., Schöne, C., Kuster, B., Schmitt, M., Aubele, M., Höfler, H., Deelder, A. M., Heck, A. J. R., Hogendoorn, P. C. W., Morreau, J., Altelaar, A. F. M., Walch, A. & McDonnell, L. A., 1 Jan 2015, In: Journal of Pathology. 235, 1, p. 3-13 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

109 Scopus citations

2014

Activation of the PI3K/AKT pathway correlates with prognosis in stage II colon cancer.

Malinowsky, K., Nitsche, U., Janssen, K. P., Bader, F. G., Späth, C., Drecoll, E., Keller, G., Höfler, H., Slotta-Huspenina, J. & Becker, K. F., 15 Apr 2014, In: British Journal of Cancer. 110, 8, p. 2081-2089 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

88 Scopus citations

A multifactorial histopathologic score for the prediction of prognosis of resected esophageal adenocarcinomas after neoadjuvant chemotherapy

Langer, R., Becker, K., Zlobec, I., Gertler, R., Sisic, L., Büchler, M., Lordick, F., Slotta-Huspenina, J., Weichert, W., Höfler, H., Feith, M. & Ott, K., Mar 2014, In: Annals of Surgical Oncology. 21, 3, p. 915-921 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

Evaluation of colon cancer histomorphology: a comparison between formalin and PAXgene tissue fixation by an international ring trial

Gündisch, S., Slotta-Huspenina, J., Verderio, P., Ciniselli, C. M., Pizzamiglio, S., Schott, C., Drecoll, E., Viertler, C., Zatloukal, K., Kap, M., Riegman, P., Esposito, I., Specht, K., Babaryka, G., Asslaber, M., Bodó, K., den Bakker, M., den Hollander, J., Fend, F. & Neumann, J. & 13 others, Reu, S., Perren, A., Langer, R., Lugli, A., Becker, I., Richter, T., Kayser, G., May, A. M., Carneiro, F., Lopes, J. M., Sobin, L., Höfler, H. & Becker, K. F., Nov 2014, In: Virchows Archiv. 465, 5, p. 509-519 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

Intraductal papillary neoplasms of the bile duct: Stepwise progression to carcinoma involves common molecular pathways

Schlitter, A. M., Born, D., Bettstetter, M., Specht, K., Kim-Fuchs, C., Riener, M. O., Jeliazkova, P., Sipos, B., Siveke, J. T., Terris, B., Zen, Y., Schuster, T., Höfler, H., Perren, A., Klöppel, G. & Esposito, I., Jan 2014, In: Modern Pathology. 27, 1, p. 73-86 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

123 Scopus citations

Multicenter immunohistochemical ALK-testing of non-small-cell lung cancer shows high concordance after harmonization of techniques and interpretation criteria

Von Laffert, M., Warth, A., Penzel, R., Schirmacher, P., Kerr, K. M., Elmberger, G., Schildhaus, H. U., Büttner, R., Lopez-Rios, F., Reu, S., Kirchner, T., Pauwels, P., Specht, K., Drecoll, E., Höfler, H., Aust, D., Baretton, G., Bubendorf, L., Stallmann, S. & Fisseler-Eckhoff, A. & 9 others, Soltermann, A., Tischler, V., Moch, H., Penault-Llorca, F., Hager, H., Schäper, F., Lenze, D., Hummel, M. & Dietel, M., 1 Nov 2014, In: Journal of Thoracic Oncology. 9, 11, p. 1685-1692 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

73 Scopus citations

Prevalence and topography of lymph node metastases in early esophageal and gastric cancer

Gertler, R., Stein, H. J., Schuster, T., Rondak, I. C., Höfler, H. & Feith, M., Jan 2014, In: Annals of Surgery. 259, 1, p. 96-101 6 p.

Research output: Contribution to journal › Article › peer-review

70 Scopus citations

2013

An ENU mutagenesis-derived mouse model with a dominant Jak1 mutation resembling phenotypes of systemic autoimmune disease

Sabrautzki, S., Janas, E., Lorenz-Depiereux, B., Calzada-Wack, J., Aguilar-Pimentel, J. A., Rathkolb, B., Adler, T., Cohrs, C., Hans, W., Diener, S., Fuchs, H., Gailus-Durner, V., Busch, D. H., Höfler, H., Ollert, M., Strom, T. M., Wolf, E., Neff, F. & Hrabě De Angelis, M., Aug 2013, In: American Journal of Pathology. 183, 2, p. 352-368 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

A specific expression profile of heat-shock proteins and glucose-regulated proteins is associated with response to neoadjuvant chemotherapy in oesophageal adenocarcinomas

Slotta-Huspenina, J., Wolff, C., Drecoll, E., Feith, M., Bettstetter, M., Malinowsky, K., Bauer, L., Becker, K., Ott, K., Höfler, H., Becker, K. F. & Langer, R., 23 Jul 2013, In: British Journal of Cancer. 109, 2, p. 370-378 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

Beteiligung und unterstützung klinischer studien und anderer wissenschaftlicher untersuchungen stellungnahme der deutschen gesellschaft für pathologie e. V.

Translated title of the contribution: Participation and support of clinical studies and other scientific investigations. Statement of the German Society for PathologyRöcken, C., Höfler, H., Hummel, M., Meyermann, R., Zietz, C. & Schirmacher, P., Sep 2013, In: Pathologe. 34, 5, p. 466-475 10 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Clinical response to chemotherapy in oesophageal adenocarcinoma patients is linked to defects in mitochondria

Aichler, M., Elsner, M., Ludyga, N., Feuchtinger, A., Zangen, V., Maier, S. K., Balluff, B., Schöne, C., Hierber, L., Braselmann, H., Meding, S., Rauser, S., Zischka, H., Aubele, M., Schmitt, M., Feith, M., Hauck, S. M., Ueffing, M., Langer, R. & Kuster, B. & 3 others, Zitzelsberger, H., Höfler, H. & Walch, A. K., Aug 2013, In: Journal of Pathology. 230, 4, p. 410-419 10 p.

Research output: Contribution to journal › Article › peer-review

72 Scopus citations

Effects of simultaneous knockdown of HER2 and PTK6 on malignancy and tumor progression in human breast cancer cells

Ludyga, N., Anastasov, N., Rosemann, M., Seiler, J., Lohmann, N., Braselmann, H., Mengele, K., Schmitt, M., Höfler, H. & Aubele, M., Apr 2013, In: Molecular Cancer Research. 11, 4, p. 381-392 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Epidermal growth factor receptor, phosphatidylinositol-3-kinase catalytic subunit/PTEN, and KRAS/NRAS/BRAF in primary resected esophageal adenocarcinomas: Loss of PTEN is associated with worse clinical outcome

Bettstetter, M., Berezowska, S., Keller, G., Walch, A., Feuchtinger, A., Slotta-Huspenina, J., Feith, M., Drecoll, E., Höfler, H. & Langer, R., May 2013, In: Human Pathology. 44, 5, p. 829-836 8 p.

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

MiR-221/-222 differentiate prognostic groups in advanced breast cancers and influence cell invasion

Falkenberg, N., Anastasov, N., Rappl, K., Braselmann, H., Auer, G., Walch, A., Huber, M., Höfig, I., Schmitt, M., Höfler, H., Atkinson, M. J. & Aubele, M., 12 Nov 2013, In: British Journal of Cancer. 109, 10, p. 2714-2723 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

53 Scopus citations

Prognostic implications of the seventh edition of the international union against cancer classification for patients with gastric cancer: The western experience of patients treated in a single-center European institution

Reim, D., Loos, M., Vogl, F., Novotny, A., Schuster, T., Langer, R., Becker, K., Höfler, H., Siveke, J., Bassermann, F., Friess, H. & Schuhmacher, C., 10 Jan 2013, In: Journal of Clinical Oncology. 31, 2, p. 263-271 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

104 Scopus citations

Rapamycin extends murine lifespan but has limited effects on aging

Neff, F., Flores-Dominguez, D., Ryan, D. P., Horsch, M., Schröder, S., Adler, T., Afonso, L. C., Aguilar-Pimentel, J. A., Becker, L., Garrett, L., Hans, W., Hettich, M. M., Holtmeier, R., Hölter, S. M., Moreth, K., Prehn, C., Puk, O., Rácz, I., Rathkolb, B. & Rozman, J. & 20 others, Naton, B., Ordemann, R., Adamski, J., Beckers, J., Bekeredjian, R., Busch, D. H., Ehninger, G., Graw, J., Höfler, H., Klingenspor, M., Klopstock, T., Ollert, M., Stypmann, J., Wolf, E., Wurst, W., Zimmer, A., Fuchs, H., Gailus-Durner, V., De Angelis, M. H. & Ehninger, D., 1 Aug 2013, In: Journal of Clinical Investigation. 123, 8, p. 3272-3291 20 p.

Research output: Contribution to journal › Article › peer-review

Open Access

325 Scopus citations

The impact of Cysteine-Rich Intestinal Protein 1 (CRIP1) in human breast cancer

Ludyga, N., Englert, S., Pflieger, K., Rauser, S., Braselmann, H., Walch, A., Auer, G., Höfler, H. & Aubele, M., 9 Apr 2013, In: Molecular Cancer. 12, 1, 28.

Research output: Contribution to journal › Article › peer-review

Open Access

42 Scopus citations

Variation in Cell Signaling Protein Expression May Introduce Sampling Bias in Primary Epithelial Ovarian Cancer

Mittermeyer, G., Malinowsky, K., Beese, C., Höfler, H., Schmalfeldt, B., Becker, K. F. & Avril, S., 28 Oct 2013, In: PLoS ONE. 8, 10, e77825.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

2012

Adenocarcinomas of the esophagogastric junction are more likely to respond to preoperative chemotherapy than distal gastric cancer

Reim, D., Gertler, R., Novotny, A., Becker, K., Meyer Zum Büschenfelde, C., Ebert, M., Dobritz, M., Langer, R., Hoefler, H., Friess, H. & Schumacher, C., Jul 2012, In: Annals of Surgical Oncology. 19, 7, p. 2108-2118 11 p.

Research output: Contribution to journal › Article › peer-review

61 Scopus citations

Antibody validation by combining immunohistochemistry and protein extraction from formalin-fixed paraffin-embedded tissues

Schuster, C., Malinowsky, K., Liebmann, S., Berg, D., Wolff, C., Tran, K., Schott, C., Reu, S., Neumann, J., Faber, C., Höfler, H., Kirchner, T., Becker, K. F. & Hlubek, F., May 2012, In: Histopathology. 60, 6 B, p. E37-E50

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Association of amphiregulin with the cetuximab sensitivity of gastric cancer cell lines

Kneissl, J., Keller, S., Lorber, T., Heindl, S., Keller, G., Drexler, I., Hapfelmeier, A., Höfler, H. & Luber, B., Aug 2012, In: International Journal of Oncology. 41, 2, p. 733-744 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

Common protein biomarkers assessed by reverse phase protein arrays show considerable intratumoral heterogeneity in breast cancer tissues

Malinowsky, K., Raychaudhuri, M., Buchner, T., Thulke, S., Wolff, C., Höfler, H., Becker, K. F. & Avril, S., 5 Jul 2012, In: PLoS ONE. 7, 7, e40285.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Cytochrome c oxidase subunit 4 isoform 2-knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology

Hüttemann, M., Lee, I., Gao, X., Pecina, P., Pecinova, A., Liu, J., Aras, S., Sommer, N., Sanderson, T. H., Tost, M., Neff, F., Aguilar-Pimentel, J. A., Becker, L., Naton, B., Rathkolb, B., Rozman, J., Favor, J., Hans, W., Prehn, C. & Puk, O. & 19 others, Schrewe, A., Sun, M., Höfler, H., Adamski, J., Bekeredjian, R., Graw, J., Adler, T., Busch, D. H., Klingenspor, M., Klopstock, T., Ollert, M., Wolf, E., Fuchs, H., Gailus-Durner, V., Hrabě De Angelis, M., Weissmann, N., Doan, J. W., Bassett, D. J. P. & Grossman, L. I., Sep 2012, In: FASEB Journal. 26, 9, p. 3916-3930 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

64 Scopus citations

Decentral gene expression analysis for ER+/Her2-breast cancer: Results of a proficiency testing program for the EndoPredict assay

Denkert, C., Kronenwett, R., Schlake, W., Bohmann, K., Penzel, R., Weber, K. E., Höfler, H., Lehmann, U., Schirmacher, P., Specht, K., Rudas, M., Kreipe, H. H., Schraml, P., Schlake, G., Bago-Horvath, Z., Tiecke, F., Varga, Z., Moch, H., Schmidt, M. & Prinzler, J. & 6 others, Kerjaschki, D., Sinn, B. V., Müller, B. M., Filipits, M., Petry, C. & Dietel, M., Mar 2012, In: Virchows Archiv. 460, 3, p. 251-259 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

86 Scopus citations

Direct molecular tissue analysis by MALDI imaging mass spectrometry in the field of gastrointestinal disease

Balluff, B., Rauser, S., Ebert, M. P., Siveke, J. T., Höfler, H. & Walch, A., Sep 2012, In: Gastroenterology. 143, 3, p. 544-549.e2

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

Evidence of prognostic relevant expression profiles of heat-shock proteins and glucose-regulated proteins in oesophageal adenocarcinomas

Slotta-Huspenina, J., Berg, D., Bauer, K., Wolff, C., Malinowsky, K., Bauer, L., Drecoll, E., Bettstetter, M., Feith, M., Walch, A., Höfler, H., Becker, K. F. & Langer, R., 24 Jul 2012, In: PLoS ONE. 7, 7, e41420.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

Expression profiling of stem cell-related genes in neoadjuvant-treated gastric cancer: A NOTCH2, GSK3B and β-catenin gene signature predicts survival

Bauer, L., Langer, R., Becker, K., Hapfelmeier, A., Ott, K., Novotny, A., Höfler, H. & Keller, G., 10 Sep 2012, In: PLoS ONE. 7, 9, e44566.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

High HSP27 and HSP70 expression levels are independent adverse prognostic factors in primary resected colon cancer

Bauer, K., Nitsche, U., Slotta-Huspenina, J., Drecoll, E., Von Weyhern, C. H., Rosenberg, R., Höfler, H. & Langer, R., Jun 2012, In: Cellular Oncology. 35, 3, p. 197-205 9 p.

Research output: Contribution to journal › Article › peer-review

53 Scopus citations

Histopathologic features of ovarian borderline tumors are not predictive of clinical outcome

Avril, S., Hahn, E., Specht, K., Hauptmann, S., Höss, C., Kiechle, M., Höfler, H. & Schmalfeldt, B., Dec 2012, In: Gynecologic Oncology. 127, 3, p. 516-524 9 p.

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Innovations in phenotyping of mouse models in the German Mouse Clinic

Fuchs, H., Gailus-Durner, V., Neschen, S., Adler, T., Afonso, L. C., Aguilar-Pimentel, J. A., Becker, L., Bohla, A., Calzada-Wack, J., Cohrs, C., Dewert, A., Fridrich, B., Garrett, L., Glasl, L., Götz, A., Hans, W., Hölter, S. M., Horsch, M., Hurt, A. & Janas, E. & 51 others, Janik, D., Kahle, M., Kistler, M., Klein-Rodewald, T., Lengger, C., Ludwig, T., Maier, H., Marschall, S., Micklich, K., Möller, G., Naton, B., Prehn, C., Puk, O., Rácz, I., Räß, M., Rathkolb, B., Rozman, J., Scheerer, M., Schiller, E., Schrewe, A., Steinkamp, R., Stöger, C., Sun, M., Szymczak, W., Treise, I., Vargas Panesso, I. L., Vernaleken, A. M., Willershäuser, M., Wolff-Muscate, A., Zeh, R., Adamski, J., Beckers, J., Bekeredjian, R., Busch, D. H., Eickelberg, O., Favor, J., Graw, J., Höfler, H., Höschen, C., Katus, H., Klingenspor, M., Klopstock, T., Neff, F., Ollert, M., Schulz, H., Stöger, T., Wolf, E., Wurst, W., Yildirim, A. Ö., Zimmer, A. & Hrabě De Angelis, M., Oct 2012, In: Mammalian Genome. 23, 9-10, p. 611-622 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

39 Scopus citations

Intratumoral heterogeneity of microRNA expression in breast cancer

Raychaudhuri, M., Schuster, T., Buchner, T., Malinowsky, K., Bronger, H., Schwarz-Boeger, U., Höfler, H. & Avril, S., Jul 2012, In: Journal of Molecular Diagnostics. 14, 4, p. 376-384 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

MALDI imaging mass spectrometry reveals COX7A2, TAGLN2 and S100-A10 as novel prognostic markers in Barrett's adenocarcinoma

Elsner, M., Rauser, S., Maier, S., Schöne, C., Balluff, B., Meding, S., Jung, G., Nipp, M., Sarioglu, H., Maccarrone, G., Aichler, M., Feuchtinger, A., Langer, R., Jütting, U., Feith, M., Küster, B., Ueffing, M., Zitzelsberger, H., Höfler, H. & Walch, A., 3 Aug 2012, In: Journal of Proteomics. 75, 15, p. 4693-4704 12 p.

Research output: Contribution to journal › Article › peer-review

89 Scopus citations

Molecular analysis of HER2 signaling in human breast cancer by functional protein pathway activation mapping

Wulfkuhle, J. D., Berg, D., Wolff, C., Langer, R., Tran, K., Illi, J., Espina, V., Pierobon, M., Deng, J., DeMichele, A., Walch, A., Bronger, H., Becker, I., Waldhör, C., Höfler, H., Esserman, L., Liotta, L. A., Becker, K. F. & Petricoin, E. F., 1 Dec 2012, In: Clinical Cancer Research. 18, 23, p. 6426-6435 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

96 Scopus citations

Nucleic acids from long-term preserved FFPE tissues are suitable for downstream analyses

Ludyga, N., Grünwald, B., Azimzadeh, O., Englert, S., Höfler, H., Tapio, S. & Aubele, M., Feb 2012, In: Virchows Archiv. 460, 2, p. 131-140 10 p.

Research output: Contribution to journal › Article › peer-review

154 Scopus citations

Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: A comparative study in transgenic mice and human tissues

Aichler, M., Seiler, C., Tost, M., Siveke, J., Mazur, P. K., Da Silva-Buttkus, P., Bartsch, D. K., Langer, P., Chiblak, S., Dürr, A., Höfler, H., Klöppel, G., Müller-Decker, K., Brielmeier, M. & Esposito, I., Apr 2012, In: Journal of Pathology. 226, 5, p. 723-734 12 p.

Research output: Contribution to journal › Article › peer-review

102 Scopus citations

Profiling signalling pathways in formalin-fixed and paraffin-embedded breast cancer tissues reveals cross-talk between EGFR, HER2, HER3 and uPAR

Berg, D., Wolff, C., Malinowsky, K., Tran, K., Walch, A., Bronger, H., Schuster, T., Höfler, H. & Becker, K. F., Jan 2012, In: Journal of Cellular Physiology. 227, 1, p. 204-212 9 p.

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Proposal for a multifactorial prognostic score that accurately classifies 3 groups of gastric carcinoma patients with different outcomes after neoadjuvant chemotherapy and surgery

Becker, K., Reim, D., Novotny, A., Zum Büschenfelde, C. M., Engel, J., Friess, H., Höfler, H. & Langer, R., Dec 2012, In: Annals of Surgery. 256, 6, p. 1002-1007 6 p.

Research output: Contribution to journal › Article › peer-review

56 Scopus citations

Relevance of MET activation and genetic alterations of KRAS and E-cadherin for cetuximab sensitivity of gastric cancer cell lines

Heindl, S., Eggenstein, E., Keller, S., Kneissl, J., Keller, G., Mutze, K., Rauser, S., Gasteiger, G., Drexler, I., Hapfelmeier, A., Höfler, H. & Luber, B., May 2012, In: Journal of Cancer Research and Clinical Oncology. 138, 5, p. 843-858 16 p.

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

S100-A10, thioredoxin, and S100-A6 as biomarkers of papillary thyroid carcinoma with lymph node metastasis identified by MALDI Imaging

Nipp, M., Elsner, M., Balluff, B., Meding, S., Sarioglu, H., Ueffing, M., Rauser, S., Unger, K., Höfler, H., Walch, A. & Zitzelsberger, H., Feb 2012, In: Journal of Molecular Medicine. 90, 2, p. 163-174 12 p.

Research output: Contribution to journal › Article › peer-review

56 Scopus citations

Tissue-based proteomics reveals FXYD3, S100A11 and GSTM3 as novel markers for regional lymph node metastasis in colon cancer

Meding, S., Balluff, B., Elsner, M., Schöne, C., Rauser, S., Nitsche, U., Maak, M., Schäfer, A., Hauck, S. M., Ueffing, M., Langer, R., Höfler, H., Friess, H., Rosenberg, R. & Walch, A., Dec 2012, In: Journal of Pathology. 228, 4, p. 459-470 12 p.

Research output: Contribution to journal › Article › peer-review

105 Scopus citations

Tumor classification of six common cancer types based on proteomic profiling by MALDI imaging

Meding, S., Nitsche, U., Balluff, B., Elsner, M., Rauser, S., Schöne, C., Nipp, M., Maak, M., Feith, M., Ebert, M. P., Friess, H., Langer, R., Höfler, H., Zitzelsberger, H., Rosenberg, R. & Walch, A., 2 Mar 2012, In: Journal of Proteome Research. 11, 3, p. 1996-2003 8 p.

Research output: Contribution to journal › Article › peer-review

116 Scopus citations

uPA and PAI-1-related signaling pathways differ between primary breast cancers and lymph node metastases

Malinowsky, K., Wolff, C., Berg, D., Schuster, T., Walch, A., Bronger, H., Mannsperger, H., Schmidt, C., Korf, U., Höfler, H. & Becker, K. F., Apr 2012, In: Translational Oncology. 5, 2, p. 98-104 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

2011

Assessment of ErbB2 (Her2) in oesophageal adenocarcinomas: Summary of a revised immunohistochemical evaluation system, bright field double in situ hybridisation and fluorescence in situ hybridisation

Langer, R., Rauser, S., Feith, M., Nährig, J. M., Feuchtinger, A., Friess, H., Höfler, H. & Walch, A., Jul 2011, In: Modern Pathology. 24, 7, p. 908-916 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

42 Scopus citations

Biomarker analysis of cetuximab plus oxaliplatin/leucovorin/5-fluorouracil in first-line metastatic gastric and oesophago-gastric junction cancer: results from a phase II trial of the Arbeitsgemeinschaft Internistische Onkologie (AIO)

Luber, B., Deplazes, J., Keller, G., Walch, A., Rauser, S., Eichmann, M., Langer, R., Höfler, H., Hegewisch-Becker, S., Folprecht, G., Wöll, E., Decker, T., Endlicher, E., Lorenzen, S., Fend, F., Peschel, C. & Lordick, F., 7 Dec 2011, In: BMC Cancer. 11, 509.

Research output: Contribution to journal › Article › peer-review

Open Access

61 Scopus citations

DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer

Mutze, K., Langer, R., Schumacher, F., Becker, K., Ott, K., Novotny, A., Hapfelmeier, A., Höfler, H. & Keller, G., Aug 2011, In: European Journal of Cancer. 47, 12, p. 1817-1825 9 p.

Research output: Contribution to journal › Article › peer-review

116 Scopus citations

Genetic aberrations in primary esophageal melanomas: Molecular analysis of c-KIT, PDGFR, KRAS, NRAS and BRAF in a series of 10 cases

Langer, R., Becker, K., Feith, M., Friess, H., Höfler, H. & Keller, G., Apr 2011, In: Modern Pathology. 24, 4, p. 495-501 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

31 Scopus citations

Heinz Höfler

Research output

Search results