Personal profile

Scientific Career

The focus of Prof. Multhoff's research (*1961) is the development of innovative immunological prognosis and therapy methods based on heat shock proteins (SFB 824: in vivo imaging, NK cells, antibodies and nanoparticles). The newly developed companion diagnostics and therapy approaches are to undergo clinical implementation in combination with conventional radiotherapy. The results of a BMBF-funded, randomised clinical phase II trial entitled: "Targeted NK cell based adjuvant immunotherapy for the treatment of patients with NSCLC after radiochemotherapy" show that NK cells make an important contribution to the control of solid tumours in combination with radiotherapy. Currently, the extent to which immune checkpoint inhibitors and CAR receptors on NK cells can further increase the success of radiation immunotherapy is being investigated. Prof. Multhoff stands scientifically for the analysis of cellular, molecular biological and immunological mechanisms in normoxic and hypoxic tumour and normal tissues after radiation exposure.

After studying biology at the LMU Munich, Prof. Multhoff obtained her doctorate in immunology in 1990 and habilitated within the framework of a Möllemann habilitation scholarship (1998). In 2002 she was appointed Professor of "Experimental Haematology" at the University Hospital Regensburg and moved to the TUM's Klinikum rechts der Isar in 2007 as Professor in the field of "Experimental Radiation Oncology and Radiation Biology". Prof. Multhoff is the founder and managing director of multimmune GmbH. She is a commission member at the German Academic Exchange Service (DAAD) and the EU as well as a member of numerous scientific societies.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

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