Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Dive into the research topics where Dieter Langosch is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Charting γ-secretase substrates by explainable AI
Breimann, S., Kamp, F., Basset, G., Abou-Ajram, C., Güner, G., Yanagida, K., Okochi, M., Müller, S. A., Lichtenthaler, S. F., Langosch, D., Frishman, D. & Steiner, H., Dec 2025, In: Nature Communications. 16, 1, 5428.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Cleavage efficiency of the intramembrane protease γ-secretase is reduced by the palmitoylation of a substrate's transmembrane domain
Aßfalg, M., Güner, G., Müller, S. A., Breimann, S., Langosch, D., Muhle-Goll, C., Frishman, D., Steiner, H. & Lichtenthaler, S. F., Feb 2024, In: FASEB Journal. 38, 2, e23442.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Cooperation of N- and C-terminal substrate transmembrane domain segments in intramembrane proteolysis by γ-secretase
Werner, N. T., Högel, P., Güner, G., Stelzer, W., Wozny, M., Aßfalg, M., Lichtenthaler, S. F., Steiner, H. & Langosch, D., Dec 2023, In: Communications Biology. 6, 1, 177.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Different transmembrane domains determine the specificity and efficiency of the cleavage activity of the γ-secretase subunit presenilin
Schmidt, F. C., Fitz, K., Feilen, L. P., Okochi, M., Steiner, H. & Langosch, D., May 2023, In: Journal of Biological Chemistry. 299, 5, 104626.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Interaction of Substrates with γ-Secretase at the Level of Individual Transmembrane Helices-A Methodological Approach
Pauli, T. M., Julius, A., Costa, F., Eschrig, S., Moosmueller, J., Fischer, L., Schanzenbach, C., Schmidt, F. C., Ortner, M. & Langosch, D., Sep 2023, In: International Journal of Molecular Sciences. 24, 18, 17 p., 14396.Research output: Contribution to journal › Article › peer-review
1 Scopus citations