Angela Krackhardt

2024

High-resolution profile of neoantigen-specific TCR activation links moderate stimulation to increased resilience of engineered TCR-T cells

Füchsl, F., Untch, J., Kavaka, V., Zuleger, G., Braun, S., Schwanzer, A., Jarosch, S., Vogelsang, C., de Andrade Krätzig, N., Gosmann, D., Öllinger, R., Giansanti, P., Hiltensperger, M., Rad, R., Busch, D. H., Beltrán, E., Bräunlein, E. & Krackhardt, A. M., Dec 2024, In: Nature Communications. 15, 1, 10520.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification

Tretter, C., de Andrade Krätzig, N., Pecoraro, M., Lange, S., Seifert, P., von Frankenberg, C., Untch, J., Zuleger, G., Wilhelm, M., Zolg, D. P., Dreyer, F. S., Bräunlein, E., Engleitner, T., Uhrig, S., Boxberg, M., Steiger, K., Slotta-Huspenina, J., Ochsenreither, S., von Bubnoff, N. & Bauer, S. & 19 others, Boerries, M., Jost, P. J., Schenck, K., Dresing, I., Bassermann, F., Friess, H., Reim, D., Grützmann, K., Pfütze, K., Klink, B., Schröck, E., Haller, B., Kuster, B., Mann, M., Weichert, W., Fröhling, S., Rad, R., Hiltensperger, M. & Krackhardt, A. M., Dec 2023, In: Nature Communications. 14, 1, 4632.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

The CAR-HEMATOTOX score as a prognostic model of toxicity and response in patients receiving BCMA-directed CAR-T for relapsed/refractory multiple myeloma

Rejeski, K., Hansen, D. K., Bansal, R., Sesques, P., Ailawadhi, S., Logue, J. M., Bräunlein, E., Cordas dos Santos, D. M., Freeman, C. L., Alsina, M., Theurich, S., Wang, Y., Krackhardt, A. M., Locke, F. L., Bachy, E., Jain, M. D., Lin, Y. & Subklewe, M., Dec 2023, In: Journal of Hematology and Oncology. 16, 1, 88.

Research output: Contribution to journal › Article › peer-review

Open Access

39 Scopus citations

The influence of metastatic patterns and tumor load on therapeutic efficacy of immunotherapy in patients with metastatic melanoma as determined by quantitative PET-parameters using [¹⁸F]-fluorodeoxyglucose PET/computed tomography

Berberich, C., Mustafa, M., Zhuwu, Y., Gaa, J., Krackhardt, A. & Nekolla, S. G., 1 Jun 2023, In: Melanoma Research. 33, 3, p. 199-207 9 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

2022

Adoptive Cellular Therapy for Multiple Myeloma Using CARand TCR-Transgenic T Cells: Response and Resistance

Füchsl, F. & Krackhardt, A. M., 1 Feb 2022, In: Cells. 11, 3, 410.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

2021

Adoptive t cell therapy is complemented by oncolytic virotherapy with fusogenic vsv-ndv in combination treatment of murine melanoma

Krabbe, T., Marek, J., Groll, T., Steiger, K., Schmid, R. M., Krackhardt, A. M. & Altomonte, J., 1 Mar 2021, In: Cancers. 13, 5, p. 1-18 18 p., 1044.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Deep learning boosts sensitivity of mass spectrometry-based immunopeptidomics

Wilhelm, M., Zolg, D. P., Graber, M., Gessulat, S., Schmidt, T., Schnatbaum, K., Schwencke-Westphal, C., Seifert, P., de Andrade Krätzig, N., Zerweck, J., Knaute, T., Bräunlein, E., Samaras, P., Lautenbacher, L., Klaeger, S., Wenschuh, H., Rad, R., Delanghe, B., Huhmer, A. & Carr, S. A. & 4 others, Clauser, K. R., Krackhardt, A. M., Reimer, U. & Kuster, B., 1 Dec 2021, In: Nature Communications. 12, 1, 3346.

Research output: Contribution to journal › Article › peer-review

Open Access

101 Scopus citations

Encorafenib, binimetinib plus pembrolizumab triplet therapy in patients with advanced BRAF^V600 mutant melanoma: safety and tolerability results from the phase I IMMU-TARGET trial

Zimmer, L., Livingstone, E., Krackhardt, A., Schultz, E. S., Göppner, D., Assaf, C., Trebing, D., Stelter, K., Windemuth-Kieselbach, C., Ugurel, S. & Schadendorf, D., Nov 2021, In: European Journal of Cancer. 158, p. 72-84 13 p.

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Functional analysis of peripheral and intratumoral neoantigen-specific TCRs identified in a patient with melanoma

Bräunlein, E., Lupoli, G., Füchsl, F., Abualrous, E. T., De Andrade Krätzig, N., Gosmann, D., Wietbrock, L., Lange, S., Engleitner, T., Lan, H., Audehm, S., Effenberger, M., Boxberg, M., Steiger, K., Chang, Y., Yu, K., Atay, C., Bassermann, F., Weichert, W. & Busch, D. H. & 4 others, Rad, R., Freund, C., Antes, I. & Krackhardt, A. M., 12 Sep 2021, In: Journal for ImmunoTherapy of Cancer. 9, 9, e002754.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Synthesis and Preclinical Evaluation of a ⁶⁸Ga-Labeled Adnectin, ⁶⁸Ga-BMS-986192, as a PET Agent for Imaging PD-L1 Expression

Robu, S., Richter, A., Gosmann, D., Seidl, C., Leung, D., Hayes, W., Cohen, D., Morin, P., Donnelly, D. J., Lipovsek, D., Bonacorsi, S. J., Smith, A., Steiger, K., Aulehner, C., Krackhardt, A. M. & Weber, W. A., 2021, In: Journal of Nuclear Medicine. 62, 9, p. 1228-1234 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

2019

Enhanced Safety and Efficacy of Oncolytic VSV Therapy by Combination with T Cell Receptor Transgenic T Cells as Carriers

Melzer, M. K., Zeitlinger, L., Mall, S., Steiger, K., Schmid, R. M., Ebert, O., Krackhardt, A. & Altomonte, J., 29 Mar 2019, In: Molecular Therapy - Oncolytics. 12, p. 26-40 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

Gene editing enables T-cell engineering to redirect antigen specificity for potent tumor rejection

Albers, J. J., Ammon, T., Gosmann, D., Audehm, S., Thoene, S., Winter, C., Secci, R., Wolf, A., Stelzl, A., Steiger, K., Ruland, J., Bassermann, F., Kupatt, C., Anton, M. & Krackhardt, A. M., 2019, In: Life Science Alliance. 2, 2, e201900367.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma

Liu, D., Schilling, B., Liu, D., Sucker, A., Livingstone, E., Jerby-Amon, L., Zimmer, L., Gutzmer, R., Satzger, I., Loquai, C., Grabbe, S., Vokes, N., Margolis, C. A., Conway, J., He, M. X., Elmarakeby, H., Dietlein, F., Miao, D., Tracy, A. & Gogas, H. & 16 others, Goldinger, S. M., Utikal, J., Blank, C. U., Rauschenberg, R., von Bubnoff, D., Krackhardt, A., Weide, B., Haferkamp, S., Kiecker, F., Izar, B., Garraway, L., Regev, A., Flaherty, K., Paschen, A., Van Allen, E. M. & Schadendorf, D., 1 Dec 2019, In: Nature Medicine. 25, 12, p. 1916-1927 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

583 Scopus citations

Key features relevant to select antigens and TCR from the MHC-mismatched repertoire to treat cancer

Audehm, S., Glaser, M., Pecoraro, M., Bräunlein, E., Mall, S., Klar, R., Effenberger, M., Albers, J., De Oliveira Bianchi, H., Peper, J., Yusufi, N., Busch, D. H., Stevanović, S., Mann, M., Antes, I. & Krackhardt, A. M., 2019, In: Frontiers in Immunology. 10, JUN, 1485.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Targeted in-vitro-stimulation reveals highly proliferative multi-virus-specific human central memory T cells as candidates for prophylactic T cell therapy

Faist, B., Schlott, F., Stemberger, C., Dennehy, K. M., Krackhardt, A., Verbeek, M., Grigoleit, G. U., Schiemann, M., Hoffmann, D., Dick, A., Martin, K., Hildebrandt, M., Busch, D. H. & Neuenhahn, M., 1 Sep 2019, In: PLoS ONE. 14, 9, e0223258.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

übersichtsarbeit: Systemtherapie des Melanoms

Translated title of the contribution: The systemic treatment of melanoma - The place of immune checkpoint inhibitors and the suppression of intracellular signal transductionTerheyden, P., Krackhardt, A. & Eigentler, T., 22 Jul 2019, In: Deutsches Arzteblatt International. 116, 29-30, p. 497-504 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

2018

Combined PET/MRI: Global Warming—Summary Report of the 6th International Workshop on PET/MRI, March 27–29, 2017, Tübingen, Germany

Bailey, D. L., Pichler, B. J., Gückel, B., Antoch, G., Barthel, H., Bhujwalla, Z. M., Biskup, S., Biswal, S., Bitzer, M., Boellaard, R., Braren, R. F., Brendle, C., Brindle, K., Chiti, A., la Fougère, C., Gillies, R., Goh, V., Goyen, M., Hacker, M. & Heukamp, L. & 16 others, Knudsen, G. M., Krackhardt, A. M., Law, I., Morris, J. C., Nikolaou, K., Nuyts, J., Ordonez, A. A., Pantel, K., Quick, H. H., Riklund, K., Sabri, O., Sattler, B., Troost, E. G. C., Zaiss, M., Zender, L. & Beyer, T., 1 Feb 2018, In: Molecular Imaging and Biology. 20, 1, p. 4-20 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

49 Scopus citations

Evaluation of the new continuous mononuclear cell collection protocol versus an older version on two different apheresis machines

Spoerl, S., Wäscher, D., Nagel, S., Peschel, C., Verbeek, M., Götze, K. & Krackhardt, A. M., Jul 2018, In: Transfusion. 58, 7, p. 1772-1780 9 p.

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Immunonkologie - ein Überblick

Translated title of the contribution: Immuno-Oncology: A Brief OverviewKobold, S., Krackhardt, A., Schlösser, H. & Wolf, D., 1 Jul 2018, In: Deutsche Medizinische Wochenschrift. 143, 14, p. 1006-1013 8 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

T-cell functionality testing is highly relevant to developing novel immuno-tracers monitoring T cells in the context of immunotherapies and revealed CD7 as an attractive target

Mayer, K. E., Mall, S., Yusufi, N., Gosmann, D., Steiger, K., Russelli, L., de Oliviera Bianchi, H., Audehm, S., Wagner, R., Bräunlein, E., Stelzl, A., Bassermann, F., Weichert, W., Weber, W., Schwaiger, M., D`Alessandria, C. & Krackhardt, A. M., 2018, In: Theranostics. 8, 21, p. 6070-6087 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

2017

Formin like 1 expression is increased on CD4 + T lymphocytes in spontaneous autoimmune uveitis

Degroote, R. L., Uhl, P. B., Amann, B., Krackhardt, A. M., Ueffing, M., Hauck, S. M. & Deeg, C. A., 10 Feb 2017, In: Journal of Proteomics. 154, p. 102-108 7 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

In-depth characterization of a TCR-specific tracer for sensitive detection of tumor-directed transgenic T cells by immuno-PET

Yusufi, N., Mall, S., Bianchi, H. D. O., Steiger, K., Reder, S., Klar, R., Audehm, S., Mustafa, M., Nekolla, S., Peschel, C., Schwaiger, M., Krackhardt, A. M. & D'Alessandria, C., 2017, In: Theranostics. 7, 9, p. 2402-2416 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Ipilimumab alone or in combination with nivolumab after progression on anti-PD-1 therapy in advanced melanoma

Zimmer, L., Apuri, S., Eroglu, Z., Kottschade, L. A., Forschner, A., Gutzmer, R., Schlaak, M., Heinzerling, L., Krackhardt, A. M., Loquai, C., Markovic, S. N., Joseph, R. W., Markey, K., Utikal, J. S., Weishaupt, C., Goldinger, S. M., Sondak, V. K., Zager, J. S., Schadendorf, D. & Khushalani, N. I., 1 Apr 2017, In: European Journal of Cancer. 75, p. 47-55 9 p.

Research output: Contribution to journal › Article › peer-review

147 Scopus citations

Isolation and functional characterization of hepatitis B virus-specific T-cell receptors as new tools for experimental and clinical use

Wisskirchen, K., Metzger, K., Schreiber, S., Asen, T., Weigand, L., Dargel, C., Witter, K., Kieback, E., Sprinzl, M. F., Uckert, W., Schiemann, M., Busch, D. H., Krackhardt, A. M. & Protzer, U., Aug 2017, In: PLoS ONE. 12, 8, e0182936.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

Patients' outcome after rescue plerixafor administration for autologous stem cell mobilization: a single-center retrospective analysis

Spoerl, S., Peter, R., Wäscher, D., Götze, K., Verbeek, M., Peschel, C. & Krackhardt, A. M., 1 Jan 2017, In: Transfusion. 57, 1, p. 115-121 7 p.

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Specific Adoptive Cellular Immunotherapy in Allogeneic Stem Cell Transplantation

Audehm, S. & Krackhardt, A. M., 1 Oct 2017, In: Oncology Research and Treatment. 40, 11, p. 691-696 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

2016

Cutaneous, gastrointestinal, hepatic, endocrine, and renal side-effects of anti-PD-1 therapy

Hofmann, L., Forschner, A., Loquai, C., Goldinger, S. M., Zimmer, L., Ugurel, S., Schmidgen, M. I., Gutzmer, R., Utikal, J. S., Göppner, D., Hassel, J. C., Meier, F., Tietze, J. K., Thomas, I., Weishaupt, C., Leverkus, M., Wahl, R., Dietrich, U., Garbe, C. & Kirchberger, M. C. & 8 others, Eigentler, T., Berking, C., Gesierich, A., Krackhardt, A. M., Schadendorf, D., Schuler, G., Dummer, R. & Heinzerling, L. M., 1 Jun 2016, In: European Journal of Cancer. 60, p. 190-209 20 p.

Research output: Contribution to journal › Article › peer-review

542 Scopus citations

Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry

Bassani-Sternberg, M., Bräunlein, E., Klar, R., Engleitner, T., Sinitcyn, P., Audehm, S., Straub, M., Weber, J., Slotta-Huspenina, J., Specht, K., Martignoni, M. E., Werner, A., Hein, R., Busch, D. H., Peschel, C., Rad, R., Cox, J., Mann, M. & Krackhardt, A. M., 21 Nov 2016, In: Nature Communications. 7, 13404.

Research output: Contribution to journal › Article › peer-review

Open Access

504 Scopus citations

Human HLA-A*02:01/CHM1⁺ allo-restricted T cell receptor transgenic CD8⁺ T Cells specifically inhibit Ewing sarcoma growth in vitro and in vivo

Blaeschke, F., Thiel, U., Kirschner, A., Thiede, M., Rubio, R. A., Schirmer, D., Kirchner, T., Richter, G. H. S., Mall, S., Klar, R., Riddell, S., Busch, D. H., Krackhardt, A., Grunewald, T. G. P. & Burdach, S., 2016, In: Oncotarget. 7, 28, p. 43267-43280 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Immuno-PET imaging of engineered human T cells in tumors

Mall, S., Yusufi, N., Wagner, R., Klar, R., Bianchi, H., Steiger, K., Straub, M., Audehm, S., Laitinen, I., Aichler, M., Peschel, C., Ziegler, S., Mustafa, M., Schwaiger, M., D'Alessandria, C. & Krackhardt, A. M., 15 Jul 2016, In: Cancer Research. 76, 14, p. 4113-4123 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

46 Scopus citations

Neurological, respiratory, musculoskeletal, cardiac and ocular side-effects of anti-PD-1 therapy

Zimmer, L., Goldinger, S. M., Hofmann, L., Loquai, C., Ugurel, S., Thomas, I., Schmidgen, M. I., Gutzmer, R., Utikal, J. S., Göppner, D., Hassel, J. C., Meier, F., Tietze, J. K., Forschner, A., Weishaupt, C., Leverkus, M., Wahl, R., Dietrich, U., Garbe, C. & Kirchberger, M. C. & 8 others, Eigentler, T., Berking, C., Gesierich, A., Krackhardt, A. M., Schadendorf, D., Schuler, G., Dummer, R. & Heinzerling, L. M., 1 Jun 2016, In: European Journal of Cancer. 60, p. 210-225 16 p.

Research output: Contribution to journal › Article › peer-review

476 Scopus citations

Transgenic antigen-specific, HLA-A*02:01-allo-restricted cytotoxic T cells recognize tumor-associated target antigen STEAP1 with high specificity

Schirmer, D., Grünewald, T. G. P., Klar, R., Schmidt, O., Wohlleber, D., Rubío, R. A., Uckert, W., Thiel, U., Bohne, F., Busch, D. H., Krackhardt, A. M., Burdach, S. & Richter, G. H. S., 2 Jun 2016, In: OncoImmunology. 5, 6, e1175795.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

2015

Long-term experiences in cryopreservation of mobilized peripheral blood stem cells using a closed-bag system: A technology with potential for broader application

Spoerl, S., Peter, R., Wäscher, D., Verbeek, M., Menzel, H., Peschel, C. & Krackhardt, A. M., Nov 2015, In: Transfusion. 55, 11, p. 2702-2708 7 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): A randomised, controlled, open-label, phase 3 trial

Weber, J. S., D'Angelo, S. P., Minor, D., Hodi, F. S., Gutzmer, R., Neyns, B., Hoeller, C., Khushalani, N. I., Miller, W. H., Lao, C. D., Linette, G. P., Thomas, L., Lorigan, P., Grossmann, K. F., Hassel, J. C., Maio, M., Sznol, M., Ascierto, P. A., Mohr, P. & Chmielowski, B. & 8 others, Bryce, A., Svane, I. M., Grob, J. J., Krackhardt, A. M., Horak, C., Lambert, A., Yang, A. S. & Larkin, J., 2015, In: Lancet Oncology. 16, 4, p. 375-384 10 p.

Research output: Contribution to journal › Article › peer-review

2283 Scopus citations

Quantitative Analysis of the Association Angle between T-cell Receptor Vα/Vβ Domains Reveals Important Features for Epitope Recognition

Hoffmann, T., Krackhardt, A. M. & Antes, I., 1 Jul 2015, In: PLoS Computational Biology. 11, 7, e1004244.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

T Cells Engineered to Express a T-Cell Receptor Specific for Glypican-3 to Recognize and Kill Hepatoma Cells In Vitro and in Mice

Dargel, C., Bassani-Sternberg, M., Hasreiter, J., Zani, F., Bockmann, J. H., Thiele, F., Bohne, F., Wisskirchen, K., Wilde, S., Sprinzl, M. F., Schendel, D. J., Krackhardt, A. M., Uckert, W., Wohlleber, D., Schiemann, M., Stemmer, K., Heikenwälder, M., Busch, D. H., Richter, G. & Mann, M. & 1 others, Protzer, U., 1 Oct 2015, In: Gastroenterology. 149, 4, p. 1042-1052 11 p., 59826.

Research output: Contribution to journal › Article › peer-review

80 Scopus citations

2014

Therapeutic targeting of naturally presented myeloperoxidase-derived HLA peptide ligands on myeloid leukemia cells by TCR-transgenic T cells

Klar, R., Schober, S., Rami, M., Mall, S., Merl, J., Hauck, S. M., Ueffing, M., Admon, A., Slotta-Huspenina, J., Schwaiger, M., Stevanović, S., Oostendorp, R. A. J., Busch, D. H., Peschel, C. & Krackhardt, A. M., 11 Dec 2014, In: Leukemia. 28, 12, p. 2355-2366 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

2013

Proteomic investigation of the interactome of FMNL1 in hematopoietic cells unveils a role in calcium-dependent membrane plasticity

Han, Y., Yu, G., Sarioglu, H., Caballero-Martinez, A., Schlott, F., Ueffing, M., Haase, H., Peschel, C. & Krackhardt, A. M., 4 Jan 2013, In: Journal of Proteomics. 78, p. 72-82 11 p.

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

TCR-ligand k_off rate correlates with the protective capacity of antigen-specific CD8⁺ T cells for adoptive transfer

Nauerth, M., Weißbrich, B., Knall, R., Franz, T., Dössinger, G., Bet, J., Paszkiewicz, P. J., Pfeifer, L., Bunse, M., Uckert, W., Holtappels, R., Gillert-Marien, D., Neuenhahn, M., Krackhardt, A., Reddehase, M. J., Riddell, S. R. & Busch, D. H., 3 Jul 2013, In: Science Translational Medicine. 5, 192, 192ra87.

Research output: Contribution to journal › Article › peer-review

Open Access

83 Scopus citations

2012

Isolation of human MHC class II-restricted T cell receptors from the autologous T-cell repertoire with potent anti-leukaemic reactivity

Weigand, L. U., Liang, X., Schmied, S., Mall, S., Klar, R., Stötzer, O. J., Salat, C., Götze, K., Mautner, J., Peschel, C. & Krackhardt, A. M., Nov 2012, In: Immunology. 137, 3, p. 226-238 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Poloxamer synperonic F108 improves cellular transduction with lentiviral vectors

Höfig, I., Atkinson, M. J., Mall, S., Krackhardt, A. M., Thirion, C. & Anastasov, N., Aug 2012, In: Journal of Gene Medicine. 14, 8, p. 549-560 12 p.

Research output: Contribution to journal › Article › peer-review

54 Scopus citations

2010

A single TCRα-chain with dominant peptide recognition in the allorestricted HER2/neu-specific T cell repertoire

Liang, X., Weigand, L. U., Schuster, I. G., Eppinger, E., Van Der Griendt, J. C., Schub, A., Leisegang, M., Sommermeyer, D., Anderl, F., Han, Y., Ellwart, J., Moosmann, A., Busch, D. H., Uckert, W., Peschel, C. & Krackhardt, A. M., 1 Feb 2010, In: Journal of Immunology. 184, 3, p. 1617-1629 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

2009

Formin-like 1 (FMNL1) is regulated by N-terminal myristoylation and induces polarized membrane blebbing

Han, Y., Eppinger, E., Schuster, I. G., Weigand, L. U., Liang, X., Kremmer, E., Peschel, C. & Krackhardt, A. M., 27 Nov 2009, In: Journal of Biological Chemistry. 284, 48, p. 33409-33417 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

53 Scopus citations

2007

Allorestricted T cells with specificity for the FMNL1-derived peptide PP2 have potent antitumor activity against hematologic and other malignancies

Schuster, I. G., Busch, D. H., Eppinger, E., Kremmer, E., Milosevic, S., Hennard, C., Kuttler, C., Ellwart, J. W., Frankenberger, B., Nößner, E., Salat, C., Bogner, C., Borkhardt, A., Kolb, H. J. & Krackhardt, A. M., 15 Oct 2007, In: Blood. 110, 8, p. 2931-2939 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

41 Scopus citations

2002

Identification of tumor-associated antigens in chronic lymphocytic leukemia by SEREX

Krackhardt, A. M., Witzens, M., Harig, S., Stephen Hodi, F., Jason Zauls, A., Chessia, M., Barrett, P. & Gribben, J. G., 15 Sep 2002, In: Blood. 100, 6, p. 2123-2131 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

118 Scopus citations

T-cell responses against chronic lymphocytic leukemia cells: Implications for immunotherapy

Krackhardt, A. M., Harig, S., Witzens, M., Broderick, R., Barrett, P. & Gribben, J. G., 1 Jul 2002, In: Blood. 100, 1, p. 167-173 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

78 Scopus citations

2001

Generation of cytotoxic T lymphocytes against native and altered peptides of human leukocyte antigen-A*0201 restricted epitopes from the human epithelial cell adhesion molecule

Trojan, A., Witzens, M., Schultze, J. L., Vonderheide, R. H., Harig, S., Krackhardt, A. M., Stahel, R. A. & Gribben, J. G., 15 Jun 2001, In: Cancer Research. 61, 12, p. 4761-4765 5 p.

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Induction of cytotoxic T-cell responses against immunoglobulin V region-derived peptides modified at human leukocyte antigen-A2 binding residues

Harig, S., Witzens, M., Krackhardt, A. M., Trojan, A., Barrett, P., Broderick, R., Jason Zauls, A. & Gribben, J. G., 15 Nov 2001, In: Blood. 98, 10, p. 2999-3005 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

59 Scopus citations

1999

Carboxypeptidase G2 rescue in a 79 year-old patient with cranial lymphoma after high-dose methotrexate induced acute renal failure

Krackhardt, A., Schwartz, S., Korfel, A. & Thiel, E., 1999, In: Leukemia and Lymphoma. 35, 5-6, p. 631-635 5 p.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Stem cell transplantation for indolent lymphoma

Krackhardt, A. & Gribben, J. G., 1999, In: Current Opinion in Hematology. 6, 6, p. 388-393 6 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Angela Krackhardt

Research output

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