Projects per year
Personal profile
Scientific Career
Professor Angela Casini completed her PhD in Chemistry at the University of Florence (Italy) in 2004, and, afterwards, moved to EPFL (Switzerland) as principal investigator funded by the Swiss National Science Foundation. Between 2011-2015 she was assistant professor at the University of Groningen (The Netherlands), holding a Rosalind Franklin Fellowship. Between 2015-2019, she was also Chair and Director of Postgraduate Taught Masters at Cardiff University (UK), before taking up her current position at TUM in 2019. At TUM, Angela is also Liesel Beckmann Distinguished Professor and Core member of the Munich Institute of Data Science (MDSI), as well as Associated Researcher of the Catalysis Research Center (CRC). Since December 2021, Angela is ad interim manager (kommissarischen Leiterin) of the Chair of Pharmaceutical Radiochemistry at TUM.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, “Carbonic Anhydrase Inhibitors with possible pharmacological applications, University of Florence
Award Date: 23 Nov 2004
Master, DNA as a target for Ruthenium(III) complexes acting as anticancer agents, University of Florence
Award Date: 19 Dec 1998
Keywords
- QD Chemistry
- Medicinal Chemistry
- Bioinorganic Chemistry
- Supramolecular Chemistry
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Collaborations and top research areas from the last five years
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UbiQancer: Functionalizing the Ubiquitin System against Cancer
Casini, A. (PI)
1/10/24 → 30/06/28
Project: Research
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SMARTdrugs: Supramolecular Agents as Radiotheranostic Drugs
Casini, A. (PI)
1/01/24 → 31/12/27
Project: Research
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Organogold compounds as “smart” residue specific chemical modifiers: towards new generation Gold-PROTACs (B03)
Casini, A. (PI)
1/01/24 → …
Project: Research
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SOCoMED: Supramolecular Organometallic and Coordination Complexes for Medical Applications
Casini, A. (PI)
1/03/23 → 28/02/27
Project: Research
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MiAMI: Machine Learning for Medicine: Accelerating Metadynamics of Supramolecular Host-Guest Complexes for Therapy and Imaging
Casini, A. (PI)
1/03/24 → 28/02/25
Project: Research
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An organogold compound impairs Leishmania amazonensis amastigotes survival and delays lesion progression in murine cutaneous leishmaniasis: Mechanistic insights
Minori, K., Gadelha, F. R., Bonsignore, R., Alcántar, G. M., Fontes, J. V., Abbehausen, C., Brioschi, M. B. C., de Sousa, L. M., Consonni, S. R., Casini, A. & Miguel, D. C., Feb 2025, In: Biochemical Pharmacology. 232, 116716.Research output: Contribution to journal › Article › peer-review
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Gold metallacages: Design principles and applications
Thomas, S. R., Willnhammer, N., Casini, A. & Moreno-Alcántar, G., 2025, (Accepted/In press) In: Chem. 102502.Research output: Contribution to journal › Review article › peer-review
Open Access -
Unraveling the Molecular Basis for G-Quadruplex-Binders to ALS/FTD-Associated G4C2 Repeats of the C9orf72 Gene
D'Anna, L., Wragg, D., Mauro, D., Rubino, S., Terenzi, A., Barone, G., Thomas, S. R., Casini, A., Bonsignore, R. & Spinello, A., 2025, (Accepted/In press) In: ChemBioChem.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
(SiFA)SeFe: A Hydrophilic Silicon-Based Fluoride Acceptor Enabling Versatile Peptidic Radiohybrid Tracers
Deiser, S., Fenzl, S., König, V., Drexler, M., Smith, L. M., George, M. E., Beck, R., Witney, T. H., Inoue, S. & Casini, A., 22 Aug 2024, In: Journal of Medicinal Chemistry. 67, 16, p. 14077-14094 18 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
A Golden Touch in the Design of Multifunctional Porphyrin Metallacages: Host-Guest Chemistry for Drug-Target Interactions
Rodríguez-Prieto, T., Wragg, D., Heiduk, N., Park, M., Strittmatter, N., Fischer, R. A., Casini, A. & Moreno-Alcántar, G., 1 Jul 2024, In: CCS Chemistry. 6, 7, p. 1662-1671 10 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations