Chair of Organic Chemistry 1

2025

Efficient and selective energy transfer photoenzymes powered by visible light

Crawshaw, R., Smithson, R., Hofer, J., Hardy, F. J., Roberts, G. W., Trimble, J. S., Kohn, A. R., Levy, C. W., Drost, D. A., Merten, C., Heyes, D. J., Obexer, R., Bach, T. & Green, A. P., 2025, (Accepted/In press) In: Nature Chemistry. 7302.

Research output: Contribution to journal › Article › peer-review

Open Access

Intramolecular ortho Photocycloaddition of 4-Substituted 7-(4′-Alkenyloxy)-1-indanones and Ensuing Reaction Cascades

Gilbert, A., Zuber, J. & Bach, T., 2025, (Accepted/In press) In: Journal of Organic Chemistry.

Research output: Contribution to journal › Article › peer-review

Open Access

Intramolecular ortho Photocycloaddition of 4-Substituted 7-(4′-Alkenyloxy)-1-indanones and Ensuing Reaction Cascades

Gilbert, A., Zuber, J. & Bach, T., 21 Mar 2025, In: Journal of Organic Chemistry. 90, 11, p. 4099-4107 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Oxetane Cleavage Pathways in the Excited State: Photochemical Kinetic Resolution as an Approach to Enantiopure Oxetanes

Pflaum, N., Pauls, M., Kumar, A., Kutta, R. J., Nuernberger, P., Hauer, J., Bannwarth, C. & Bach, T., 23 Apr 2025, In: Journal of the American Chemical Society. 147, 16, p. 13893-13904 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Oxetane Cleavage Pathways in the Excited State: Photochemical Kinetic Resolution as an Approach to Enantiopure Oxetanes

Pflaum, N., Pauls, M., Kumar, A., Kutta, R. J., Nuernberger, P., Hauer, J., Bannwarth, C. & Bach, T., 2025, (Accepted/In press) In: Journal of the American Chemical Society.

Research output: Contribution to journal › Article › peer-review

Open Access

Photocatalytic reductive incorporation of carbon dioxide into double bonds

Deeprose, M. J. & Bach, T., 3 Apr 2025, In: Chemical Communications. 61, 37, p. 6791-6794 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Photochemical Deracemization of 4,7-Diaza-1-isoindolinones by Unidirectional Hydrogen Atom Shuttling

Freund, P., Pauls, M., Babushkina, D., Pickl, T., Bannwarth, C. & Bach, T., 15 Jan 2025, In: Journal of the American Chemical Society. 147, 2, p. 1434-1439 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Stereochemical Editing at sp³-Hybridized Carbon Centers by Reversible, Photochemically Triggered Hydrogen Atom Transfer

Iglhaut, M. & Bach, T., 4 Mar 2025, In: Accounts of Chemical Research. 58, 5, p. 777-786 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Total Synthesis and Configuration Assignment of (+)-Myxoquaterine-450

Löhr, J., Ortmann, S., Popoff, A., Müller, R. & Bach, T., 21 Jan 2025, In: Angewandte Chemie International Edition in English. 64, 4, e202416941.

Research output: Contribution to journal › Article › peer-review

Open Access

2024

Discovery of the Pendulisporaceae: An extremotolerant myxobacterial family with distinct sporulation behavior and prolific specialized metabolism

Garcia, R., Popoff, A., Bader, C. D., Löhr, J., Walesch, S., Walt, C., Boldt, J., Bunk, B., Haeckl, F. P. J., Gunesch, A. P., Birkelbach, J., Nübel, U., Pietschmann, T., Bach, T. & Müller, R., 8 Aug 2024, In: Chem. 10, 8, p. 2518-2537 20 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Enantioselective Intramolecular ortho Photocycloaddition Reactions of 2-Acetonaphthones

Yan, P., Stegbauer, S., Wu, Q., Kolodzeiski, E., Stein, C. J., Lu, P. & Bach, T., 22 Mar 2024, In: Angewandte Chemie International Edition in English. 63, 13, e202318126.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Intermolecular Enantioselective Amination Reactions Mediated by Visible Light and a Chiral Iron Porphyrin Complex

Ahmed, H., Ghosh, B., Breitenlechner, S., Feßner, M., Merten, C. & Bach, T., 2024, (Accepted/In press) In: Angewandte Chemie International Edition in English.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Intramolecular Cobalt Porphyrin-Catalyzed Alkylation of 1-Isoindolinones by Site-Selective Insertion into a C(sp³)-H Bond

Buchelt, C., Zuber, J. & Bach, T., 2024, (Accepted/In press) In: Organic Letters.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Photochemical Deracemization of N-Carboxyanhydrides En Route to Chiral α-Amino Acid Derivatives

Iglhaut, M., Freund, P. & Bach, T., 2024, (Accepted/In press) In: Angewandte Chemie International Edition in English.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Remote Enantioselective Epoxidation Reactions Catalyzed by Chiral Iron Porphyrin Complexes with a Hydrogen-Bonding Site

Ahmed, H., Pöthig, A., Truong, K. N. & Bach, T., 13 May 2024, In: Synlett. 35, 9, p. 983-988 6 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Synthesis and biological evaluation of vioprolide B and its dehydrobutyrine-glycine analogue

Osorio Reineke, N., Elsen, F. A. V., Grab, H. A., Mostert, D., Sieber, S. A. & Bach, T., 15 Jul 2024, In: Chemical Communications. 60, 63, p. 8272-8275 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Synthesis of a Potential Precursor (Northern Fragment) for the Cyclic Depsipeptides Vioprolides A and C

Reineke, N. O., Grab, H. A. & Bach, T., 2024, (Accepted/In press) In: Synthesis.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

2023

Creating a Defined Chirality in Amino Acids and Cyclic Dipeptides by Photochemical Deracemization

Großkopf, J., Plaza, M., Kutta, R. J., Nuernberger, P. & Bach, T., 20 Nov 2023, In: Angewandte Chemie International Edition in English. 62, 47, e202313606.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Diastereoselective, Lewis acid-mediated Diels-Alder reactions of allenoic acid derivatives and 1,3-cyclopentadienes

Harvey, F. M., Heidecker, A. H., Merten, C. & Bach, T., 8 May 2023, In: Organic and Biomolecular Chemistry. 21, 21, p. 4422-4428 7 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Enantiodivergent Photochemical Rearrangements Due to Different Coordination Modes at an Oxazaborolidine Lewis Acid Catalyst

Leverenz, M., Brockmann, H., Dreuw, A., Bach, T. & Storch, G., 5 May 2023, In: ACS Catalysis. 13, 9, p. 5896-5905 10 p.

Research output: Contribution to journal › Article › peer-review

Enantioselective, Intermolecular [_π2+_σ2] Photocycloaddition Reactions of 2(1H)-Quinolones and Bicyclo[1.1.0]butanes

de Robichon, M., Kratz, T., Beyer, F., Zuber, J., Merten, C. & Bach, T., 2023, (Accepted/In press) In: Journal of the American Chemical Society.

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Multifaceted View on the Mechanism of a Photochemical Deracemization Reaction

Kutta, R. J., Großkopf, J., van Staalduinen, N., Seitz, A., Pracht, P., Breitenlechner, S., Bannwarth, C., Nuernberger, P. & Bach, T., 1 Feb 2023, In: Journal of the American Chemical Society. 145, 4, p. 2354-2363 10 p.

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Photochemical Deracemization of 3-Substituted Oxindoles

Großkopf, J., Heidecker, A. A. & Bach, T., 24 Jul 2023, In: Angewandte Chemie International Edition in English. 62, 30, e202305274.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Photochemical Isomerization of Cyclohept-1-ene-1-carbaldehyde: Strain-Release Cycloadditions and Ene Reactions

Schwinger, D. P., Pickl, T. & Bach, T., 1 Sep 2023, In: Journal of Organic Chemistry. 88, 17, p. 12844-12852 9 p.

Research output: Contribution to journal › Article › peer-review

Photochemical Ring Contraction of 5,5-Dialkylcyclopent-2-enones and in situ Trapping by Primary Amines

Jeremias, N., Peschel, M. T., Jaschke, C., de Vivie-Riedle, R. & Bach, T., 19 May 2023, In: Journal of Organic Chemistry. 88, 10, p. 6294-6303 10 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Synthesis of Boronates with a Protoilludane Skeleton

Proessdorf, J., Jandl, C., Pickl, T. & Bach, T., 6 Feb 2023, In: Synthesis. 55, 15, p. 2311-2318 8 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Total Synthesis of (−)-5-Deoxyenterocin and Attempted Late-Stage Functionalization Reactions

Koser, L. & Bach, T., 13 Oct 2023, In: Chemistry - A European Journal. 29, 57, e202301996.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Total Synthesis of (+)-Prezizaan-15-ol, (+)-Jinkohol II, and (+)-Jinkoholic Acid

Rauscher, N., Jandl, C. & Bach, T., 16 Jun 2023, In: Organic Letters. 25, 23, p. 4247-4251 5 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

2022

Absolute Configuration of the Polyketide Natural Product (-)-Enterocin

Koser, L., Grassin, C., Merten, C. & Bach, T., 30 Sep 2022, In: Organic Letters. 24, 38, p. 6903-6907 5 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

All-cis Saturated 2,5-Diketopiperazines by a Diastereoselective Rhodium-Catalyzed Arene Hydrogenation

Schiwek, C. H., Jandl, C. & Bach, T., 18 Mar 2022, In: ACS Catalysis. 12, 6, p. 3628-3633 6 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Arene Activation through Iminium Ions: Product Diversity from Intramolecular Photocycloaddition Reactions

Proessdorf, J., Jandl, C., Pickl, T. & Bach, T., 4 Oct 2022, In: Angewandte Chemie International Edition in English. 61, 40, e202208329.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Bicyclo[2.1.1]hexanes by Visible Light-Driven Intramolecular Crossed [2 + 2] Photocycloadditions

Rigotti, T. & Bach, T., 9 Dec 2022, In: Organic Letters. 24, 48, p. 8821-8825 5 p.

Research output: Contribution to journal › Article › peer-review

60 Scopus citations

Chiral Lewis acid catalysis in a visible light-triggered cycloaddition/rearrangement cascade

Stegbauer, S., Jandl, C. & Bach, T., 23 Sep 2022, In: Chemical Science. 13, 40, p. 11856-11862 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Diels-Alder Reaction of Photochemically Generated (E)-Cyclohept-2-enones: Diene Scope, Reaction Pathway, and Synthetic Application

Schwinger, D. P., Peschel, M. T., Jaschke, C., Jandl, C., De Vivie-Riedle, R. & Bach, T., 1 Apr 2022, In: Journal of Organic Chemistry. 87, 7, p. 4838-4851 14 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Enantioselective crossed intramolecular [2+2] photocycloaddition reactions mediated by a chiral chelating Lewis acid

Rigotti, T., Schwinger, D. P., Graßl, R., Jandl, C. & Bach, T., 28 Feb 2022, In: Chemical Science. 13, 8, p. 2378-2384 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

Keeping the name clean: [2 + 2] photocycloaddition

Sivaguru, J., Bach, T. & Ramamurthy, V., Aug 2022, In: Photochemical and Photobiological Sciences. 21, 8, p. 1333-1340 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Photocatalytic Spirocyclization of 2-Alk-ω-enyl-Substituted Cycloalkane-1,3-diones

Hofer, J., Pecho, F. & Bach, T., 28 Nov 2022, In: Synlett. 34, 9, p. 1063-1067 5 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Photochemical Deracemization of Chiral Alkenes via Triplet Energy Transfer

Kratz, T., Steinbach, P., Breitenlechner, S., Storch, G., Bannwarth, C. & Bach, T., 15 Jun 2022, In: Journal of the American Chemical Society. 144, 23, p. 10133-10138 6 p.

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Photoinduced B-Cl Bond Fission in Aldehyde-BCl₃Complexes as a Mechanistic Scenario for C-H Bond Activation

Schwinger, D. P., Peschel, M. T., Rigotti, T., Kabaciński, P., Knoll, T., Thyrhaug, E., Cerullo, G., Hauer, J., De Vivie-Riedle, R. & Bach, T., 19 Oct 2022, In: Journal of the American Chemical Society. 144, 41, p. 18927-18937 11 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Rhodium(CAAC)-Catalyzed Arene Hydrogenation of Benzo-Fused N-Heterocycles to Saturated Building Blocks with an all-cis Configuration

Schiwek, C. H., Stegbauer, S., Pickl, T. & Bach, T., 4 Oct 2022, In: Advanced Synthesis and Catalysis. 364, 19, p. 3360-3365 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Synthetic Studies towards Pyrido[1,2- a ]azepine Stemona Alkaloids

Morgenstern, M., Mayer, C., Pöthig, A. & Bach, T., 23 Mar 2022, In: Synthesis. 55, 11, p. 1671-1689 19 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

The Awakening of a Sleeping Beauty: The ortho Photocycloaddition in the Total Synthesis of Protoilludane- and Prezizaene-Type Sesquiterpenes

Gilbert, A. & Bach, T., 20 May 2022, In: Synlett. 34, 12, p. 1343-1355 13 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Total Synthesis of Pulvomycin D

Fritz, L., Wienhold, S., Hackl, S. & Bach, T., 13 Jan 2022, In: Chemistry - A European Journal. 28, 3, e202104064.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Visible Light-Induced Regio- and Enantiodifferentiating [2 + 2] Photocycloaddition of 1,4-Naphthoquinones Mediated by Oppositely Coordinating 1,3,2-Oxazaborolidine Chiral Lewis Acid

Shimizu, N., Shigemitsu, H., Kida, T., Bach, T. & Mori, T., 17 Jun 2022, In: Journal of Organic Chemistry. 87, 12, p. 8071-8083 13 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Visible Light-Mediated Dearomative Hydrogen Atom Abstraction/ Cyclization Cascade of Indoles

Xiong, Y., Großkopf, J., Jandl, C. & Bach, T., 25 Apr 2022, In: Angewandte Chemie International Edition in English. 61, 18, e202200555.

Research output: Contribution to journal › Article › peer-review

Open Access

35 Scopus citations

2021

Biomimetic Total Synthesis of Enterocin

Koser, L., Lechner, V. M. & Bach, T., 6 Sep 2021, In: Angewandte Chemie International Edition in English. 60, 37, p. 20269-20273 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Concise Total Synthesis of Agarozizanol B via a Strained Photocascade Intermediate

Rauscher, N., Næsborg, L., Jandl, C. & Bach, T., 2 Nov 2021, In: Angewandte Chemie International Edition in English. 60, 45, p. 24039-24042 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Enantioselective, Visible Light Mediated Aza Paternò–Büchi Reactions of Quinoxalinones

Li, X., Großkopf, J., Jandl, C. & Bach, T., 1 Feb 2021, In: Angewandte Chemie International Edition in English. 60, 5, p. 2684-2688 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

66 Scopus citations

Enantioselective [2 + 2] Photocycloaddition via Iminium Ions: Catalysis by a Sensitizing Chiral Brønsted Acid

Pecho, F., Sempere, Y., Gramüller, J., Hörmann, F. M., Gschwind, R. M. & Bach, T., 30 Jun 2021, In: Journal of the American Chemical Society. 143, 25, p. 9350-9354 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

62 Scopus citations

Enantioselective Synthesis of Diaryl Sulfoxides Enabled by Molecular Recognition

Burg, F., Buchelt, C., Kreienborg, N. M., Merten, C. & Bach, T., 5 Mar 2021, In: Organic Letters. 23, 5, p. 1829-1834 6 p.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Chair of Organic Chemistry 1

Research output

Search results