Department of Preclinical Medicine

2025

Embedded Ethics in Practice: A Toolbox for Integrating the Analysis of Ethical and Social Issues into Healthcare AI Research

Willem, T., Fritzsche, M. C., Zimmermann, B. M., Sierawska, A., Breuer, S., Braun, M., Ruess, A. K., Bak, M., Schönweitz, F. B., Meier, L. J., Fiske, A., Tigard, D., Müller, R., McLennan, S. & Buyx, A., Feb 2025, In: Science and Engineering Ethics. 31, 1, 3.

Research output: Contribution to journal › Article › peer-review

Open Access

Homologous recombination deficiency in ovarian cancer: Global expert consensus on testing and a comparison of companion diagnostics

Quesada, S., Penault-Llorca, F., Matias-Guiu, X., Banerjee, S., Barberis, M., Coleman, R. L., Colombo, N., DeFazio, A., McNeish, I. A., Nogueira-Rodrigues, A., Oaknin, A., Pignata, S., Pujade-Lauraine, É., Rouleau, É., Ryška, A., Van Der Merwe, N., Van Gorp, T., Vergote, I., Weichert, W. & Wu, X. & 2 others, Ray-Coquard, I. & Pujol, P., 17 Jan 2025, In: European Journal of Cancer. 215, 115169.

Research output: Contribution to journal › Article › peer-review

Impact of signal-to-noise ratio and contrast definition on the sensitivity assessment and benchmarking of fluorescence molecular imaging systems

Kriukova, E., LaRochelle, E., Pfefer, T. J., Kanniyappan, U., Gioux, S., Pogue, B., Ntziachristos, V. & Gorpas, D., 1 Jan 2025, In: Journal of Biomedical Optics. 30, p. S13703

Research output: Contribution to journal › Article › peer-review

Open Access

Novel digital droplet inverse PCR assay shows that natural clearance of hepatitis B infection is associated with fewer viral integrations

Li, D., Ho, V., Teng, C. F., Tsai, H. W., Liu, Y., Bae, S., Ajoyan, H., Wettengel, J. M., Protzer, U., Gloss, B. S., Rockett, R. J., Al Asady, R., Li, J., So, S., George, J., Douglas, M. W. & Tu, T., 2025, In: Emerging Microbes and Infections. 14, 1, 2450025.

Research output: Contribution to journal › Article › peer-review

Open Access

Radiosensitizing capacity of fenofibrate in glioblastoma cells depends on lipid metabolism

Alkotub, B., Bauer, L., Bashiri Dezfouli, A., Hachani, K., Ntziachristos, V., Multhoff, G. & Kafshgari, M. H., Feb 2025, In: Redox Biology. 79, 103452.

Research output: Contribution to journal › Article › peer-review

Open Access

Towards routine proteome profiling of FFPE tissue: insights from a 1,220-case pan-cancer study

Tüshaus, J., Eckert, S., Schliemann, M., Zhou, Y., Pfeiffer, P., Halves, C., Fusco, F., Weigel, J., Hönikl, L., Butenschön, V., Todorova, R., Rauert-Wunderlich, H., The, M., Rosenwald, A., Heinemann, V., Holch, J., Steiger, K., Delbridge, C., Meyer, B. & Weichert, W. & 3 others, Mogler, C., Kuhn, P. H. & Kuster, B., 2 Jan 2025, In: EMBO Journal. 44, 1, p. 304-329 26 p., 5707.

Research output: Contribution to journal › Article › peer-review

Open Access

2024

(Predictable) performance bias in unsupervised anomaly detection

Meissen, F., Breuer, S., Knolle, M., Buyx, A., Müller, R., Kaissis, G., Wiestler, B. & Rückert, D., Mar 2024, In: eBioMedicine. 101, 105002.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

AAPM Task Group Report 311: Guidance for performance evaluation of fluorescence-guided surgery systems

Pogue, B. W., Zhu, T. C., Ntziachristos, V., Wilson, B. C., Paulsen, K. D., Gioux, S., Nordstrom, R., Pfefer, T. J., Tromberg, B. J., Wabnitz, H., Yodh, A., Chen, Y. & Litorja, M., Feb 2024, In: Medical Physics. 51, 2, p. 740-771 32 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Acceptance of Social Media Recruitment for Clinical Studies Among Patients With Hepatitis B: Mixed Methods Study

Willem, T., Zimmermann, B. M., Matthes, N., Rost, M. & Buyx, A., 2024, In: Journal of Medical Internet Research. 26, e54034.

Research output: Contribution to journal › Article › peer-review

Open Access

Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation

Saller, B. S., Wöhrle, S., Fischer, L., Dufossez, C., Ingerl, I. L., Kessler, S., Mateo-Tortola, M., Gorka, O., Lange, F., Cheng, Y., Neuwirt, E., Marada, A., Koentges, C., Urban, C., Aktories, P., Reuther, P., Giese, S., Kirschnek, S., Mayer, C. & Pilic, J. & 37 others, Falquez-Medina, H., Oelgeklaus, A., Deepagan, V. G., Shojaee, F., Zimmermann, J. A., Weber, D., Tai, Y. H., Crois, A., Ciminski, K., Peyronnet, R., Brandenburg, K. S., Wu, G., Baumeister, R., Heimbucher, T., Rizzi, M., Riedel, D., Helmstädter, M., Buescher, J., Neumann, K., Misgeld, T., Kerschensteiner, M., Walentek, P., Kreutz, C., Maurer, U., Rambold, A. S., Vince, J. E., Edlich, F., Malli, R., Häcker, G., Kierdorf, K., Meisinger, C., Köttgen, A., Jakobs, S., Weber, A. N. R., Schwemmle, M., Groß, C. J. & Groß, O., 2024, (Accepted/In press) In: Immunity.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Adenoviral fiber-knob based vaccination elicits efficient neutralizing antibodies and T cell responses against adenovirus infection

Orabi, A., Shameli, K., Protzer, U. & Moeini, H., 7 Oct 2024, In: Virology Journal. 21, 1, p. 246 1 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Advances in preclinical TCR characterization: leveraging cell avidity to identify functional TCRs

Carr, A., Mateyka, L. M., Scheu, S. J. C., Bici, A., Paijmans, J., Reijmers, R. M., Dieminger, N., Dildebekova, S., Hamed, N., Wagner, K., Busch, D. H. & D'Ippolito, E., 1 Jul 2024, In: Biological Chemistry. 405, 7-8, p. 517-529 13 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection

Bosch, M., Kallin, N., Donakonda, S., Zhang, J. D., Wintersteller, H., Hegenbarth, S., Heim, K., Ramirez, C., Fürst, A., Lattouf, E. I., Feuerherd, M., Chattopadhyay, S., Kumpesa, N., Griesser, V., Hoflack, J. C., Siebourg-Polster, J., Mogler, C., Swadling, L., Pallett, L. J. & Meiser, P. & 36 others, Manske, K., de Almeida, G. P., Kosinska, A. D., Sandu, I., Schneider, A., Steinbacher, V., Teng, Y., Schnabel, J., Theis, F., Gehring, A. J., Boonstra, A., Janssen, H. L. A., Vandenbosch, M., Cuypers, E., Öllinger, R., Engleitner, T., Rad, R., Steiger, K., Oxenius, A., Lo, W. L., Klepsch, V., Baier, G., Holzmann, B., Maini, M. K., Heeren, R., Murray, P. J., Thimme, R., Herrmann, C., Protzer, U., Böttcher, J. P., Zehn, D., Wohlleber, D., Lauer, G. M., Hofmann, M., Luangsay, S. & Knolle, P. A., 25 Jul 2024, In: Nature. 631, 8022, p. 867-875 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

A mass cytometry method pairing T cell receptor and differentiation state analysis

Garcia Castillo, J., DeBarge, R., Mende, A., Tenvooren, I., Marquez, D. M., Straub, A., Busch, D. H., Spitzer, M. H. & DuPage, M., Sep 2024, In: Nature Immunology. 25, 9, p. 1754-1763 10 p.

Research output: Contribution to journal › Article › peer-review

A multiserological line assay to potentially discriminate current from past Helicobacter pylori infection

Li, Z. X., Bronny, K., Formichella, L., Mejías-Luque, R., Burrell, T., Macke, L., Lang, U., Vasapolli, R., Hysenaj, O., Stallforth, I., Vieth, M., You, W. C., Zhang, Y., Suerbaum, S., Schulz, C., Pan, K. F. & Gerhard, M., Jan 2024, In: Clinical Microbiology and Infection. 30, 1, p. 114-121 8 p.

Research output: Contribution to journal › Article › peer-review

Analytical and clinical evaluation of a novel real-time PCR-based detection kit for Mpox virus

Bunse, T., Ziel, A., Hagen, P., Rigopoulos, G., Yasar, U., Inan, H., Köse, G., Eigner, U., Kaiser, R., Bardeck, N., Köffer, J., Kolb, M., Ren, X., Tan, D., Dai, L., Protzer, U. & Wettengel, J. M., Dec 2024, In: Medical Microbiology and Immunology. 213, 1, 18.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

A noninvasive multianalytical approach establishment for risk assessment and gastric cancer screening

Fan, X. H., Zhang, Y., Wang, P., Song, Q. Q., Wang, M., Mejias-Luque, R., Li, Z. X., Zhou, T., Zhang, J. Y., Liu, W. D., Zhang, L. F., Li, W. Q., You, W. C., Gerhard, M., Jiao, Y. C., Wang, X. B. & Pan, K. F., 15 Mar 2024, In: International Journal of Cancer. 154, 6, p. 1111-1123 13 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Arsenic trioxide impacts hepatitis B virus core nuclear localization and efficiently interferes with HBV infection

Hofmann, S., Luther, J., Plank, V., Oswald, A., Mai, J., Simons, I., Miller, J., Falcone, V., Hansen-Palmus, L., Hengel, H., Nassal, M., Protzer, U. & Schreiner, S., May 2024, In: Microbiology Spectrum. 12, 5

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Autoantigen-specific CD4⁺ T cells acquire an exhausted phenotype and persist in human antigen-specific autoimmune diseases

Saggau, C., Bacher, P., Esser, D., Rasa, M., Meise, S., Mohr, N., Kohlstedt, N., Hutloff, A., Schacht, S. S., Dargvainiene, J., Martini, G. R., Stürner, K. H., Schröder, I., Markewitz, R., Hartl, J., Hastermann, M., Duchow, A., Schindler, P., Becker, M. & Bautista, C. & 27 others, Gottfreund, J., Walter, J., Polansky, J. K., Yang, M., Naghavian, R., Wendorff, M., Schuster, E. M., Dahl, A., Petzold, A., Reinhardt, S., Franke, A., Wieczorek, M., Henschel, L., Berger, D., Heine, G., Holtsche, M., Häußler, V., Peters, C., Schmidt, E., Fillatreau, S., Busch, D. H., Wandinger, K. P., Schober, K., Martin, R., Paul, F., Leypoldt, F. & Scheffold, A., 8 Oct 2024, In: Immunity. 57, 10, p. 2416-2432.e8

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation

Thiele Orberg, E., Meedt, E., Hiergeist, A., Xue, J., Heinrich, P., Ru, J., Ghimire, S., Miltiadous, O., Lindner, S., Tiefgraber, M., Göldel, S., Eismann, T., Schwarz, A., Göttert, S., Jarosch, S., Steiger, K., Schulz, C., Gigl, M., Fischer, J. C. & Janssen, K. P. & 17 others, Quante, M., Heidegger, S., Herhaus, P., Verbeek, M., Ruland, J., van den Brink, M. R. M., Weber, D., Edinger, M., Wolff, D., Busch, D. H., Kleigrewe, K., Herr, W., Bassermann, F., Gessner, A., Deng, L., Holler, E. & Poeck, H., Jan 2024, In: Nature Cancer. 5, 1, p. 187-208 22 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4

Afzali, A. M., Nirschl, L., Sie, C., Pfaller, M., Ulianov, O., Hassler, T., Federle, C., Petrozziello, E., Kalluri, S. R., Chen, H. H., Tyystjärvi, S., Muschaweckh, A., Lammens, K., Delbridge, C., Büttner, A., Steiger, K., Seyhan, G., Ottersen, O. P., Öllinger, R. & Rad, R. & 16 others, Jarosch, S., Straub, A., Mühlbauer, A., Grassmann, S., Hemmer, B., Böttcher, J. P., Wagner, I., Kreutzfeldt, M., Merkler, D., Pardàs, I. B., Schmidt Supprian, M., Buchholz, V. R., Heink, S., Busch, D. H., Klein, L. & Korn, T., 14 Mar 2024, In: Nature. 627, 8003, p. 407-415 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Benchmarking whole exome sequencing in the German network for personalized medicine

Menzel, M., Martis-Thiele, M., Goldschmid, H., Ott, A., Romanovsky, E., Siemanowski-Hrach, J., Seillier, L., Brüchle, N. O., Maurer, A., Lehmann, K. V., Begemann, M., Elbracht, M., Meyer, R., Dintner, S., Claus, R., Meier-Kolthoff, J. P., Blanc, E., Möbs, M., Joosten, M. & Benary, M. & 92 others, Basitta, P., Hölscher, F., Tischler, V., Groß, T., Kutz, O., Prause, R., William, D., Horny, K., Goering, W., Sivalingam, S., Borkhardt, A., Blank, C., Junk, S. V., Yasin, L., Moskalev, E. A., Carta, M. G., Ferrazzi, F., Tögel, L., Wolter, S., Adam, E., Matysiak, U., Rosenthal, T., Dönitz, J., Lehmann, U., Schmidt, G., Bartels, S., Hofmann, W., Hirsch, S., Dikow, N., Göbel, K., Banan, R., Hamelmann, S., Fink, A., Ball, M., Neumann, O., Rehker, J., Kloth, M., Murtagh, J., Hartmann, N., Jurmeister, P., Mock, A., Kumbrink, J., Jung, A., Mayr, E. M., Jacob, A., Trautmann, M., Kirmse, S., Falkenberg, K., Ruckert, C., Hirsch, D., Immel, A., Dietmaier, W., Haack, T., Marienfeld, R., Fürstberger, A., Niewöhner, J., Gerstenmaier, U., Eberhardt, T., Greif, P. A., Appenzeller, S., Maurus, K., Doll, J., Jelting, Y., Jonigk, D., Märkl, B., Beule, D., Horst, D., Wulf, A. L., Aust, D., Werner, M., Reuter-Jessen, K., Ströbel, P., Auber, B., Sahm, F., Merkelbach-Bruse, S., Siebolts, U., Roth, W., Lassmann, S., Klauschen, F., Gaisa, N. T., Weichert, W., Evert, M., Armeanu-Ebinger, S., Ossowski, S., Schroeder, C., Schaaf, C. P., Malek, N., Schirmacher, P., Kazdal, D., Pfarr, N., Budczies, J. & Stenzinger, A., Nov 2024, In: European Journal of Cancer. 211, 114306.

Research output: Contribution to journal › Article › peer-review

Open Access

Bragg grating etalon-based optical fiber for ultrasound and optoacoustic detection

La, T. A., Ülgen, O., Shnaiderman, R. & Ntziachristos, V., Dec 2024, In: Nature Communications. 15, 1, 7521.

Research output: Contribution to journal › Article › peer-review

Open Access

Carboxyl ester lipase hybrid 1 (CEL-HYB1) haplotypes confer varying risk for chronic pancreatitis

Berke, G., Sándor, M., Xiao, X. K., Lowe, M. E., Ewers, M., Erőss, B., Masson, E., Németh, B. C., Vincze, Á., Czakó, L., Rygiel, A. M., Rosendahl, J., Chen, J. M., Witt, H., Hegyi, P., Sahin-Tóth, M. & Hegyi, E., Dec 2024, In: Scientific Reports. 14, 1, 30965.

Research output: Contribution to journal › Article › peer-review

Open Access

CARs derived from broadly neutralizing, human monoclonal antibodies identified by single B cell sorting target hepatitis B virus-positive cells

Schreiber, S., Dressler, L. S., Loffredo-Verde, E., Asen, T., Färber, S., Wang, W., Groll, T., Chakraborty, A., Kolbe, F., Kreer, C., Kosinska, A. D., Simon, S., Urban, S., Klein, F., Riddell, S. R. & Protzer, U., 2024, In: Frontiers in Immunology. 15, 1340619.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

CD20-bispecific antibodies improve response to CD19-CAR T cells in lymphoma in vitro and CLL in vivo models

Brinkmann, B. J., Floerchinger, A., Schniederjohann, C., Roider, T., Coelho, M., Mack, N., Bruch, P. M., Liebers, N., Dötsch, S., Busch, D. H., Schmitt, M., Neumann, F., Roessner, P. M., Seiffert, M. & Dietrich, S., 15 Aug 2024, In: Blood. 144, 7, p. 784-789 6 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Checkpoint Inhibitor Monotherapy in Potentially Trial-Eligible or Trial-Ineligible Patients With Metastatic NSCLC in the German Prospective CRISP Registry Real-World Cohort (AIO-TRK-0315)

CRISP Registry Group, Apr 2024, In: JTO Clinical and Research Reports. 5, 4, 100626.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Clinical and immunological benefits of full primary COVID-19 vaccination in individuals with SARS-CoV-2 breakthrough infections: A prospective cohort study in non-hospitalized adults

CoVaKo Study Group, Feb 2024, In: Journal of Clinical Virology. 170, 105622.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Clinical and immunological outcomes of SARS-CoV-2-infected vaccine responders, vaccine non-responders, and unvaccinated patients evaluated for neutralizing monoclonal antibody treatment at a single German tertiary care center: a retrospective cohort study with prospective follow-up

Triebelhorn, J., Schneider, J., Spinner, C. D., Iakoubov, R., Voit, F., Wagner, L., Erber, J., Rothe, K., Berthele, A., Pernpeintner, V., Strauß, E. M., Renders, L., Willmann, A., Minic, M., Vogel, E., Christa, C., Hoffmann, D., Protzer, U. & Jeske, S. D., Jun 2024, In: Infection. 52, 3, p. 1143-1151 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Co-infection of Helicobacter Pylori and intestinal parasites in children of selected Low-income communities in Lagos State, Nigeria

Aniekwe, O., Jolaiya, T., Ajayi, A., Adeleye, I. A., Gerhard, M. & Smith, S. I., Aug 2024, In: Parasitology International. 101, 102896.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Comparing the Representation of a Simple Visual Stimulus across the Cerebellar Network

Prat, O., Petrucco, L., Štih, V. & Portugues, R., Jul 2024, In: eNeuro. 11, 7, ENEURO.0023-24.2024.

Research output: Contribution to journal › Article › peer-review

Concordance between an FDA-approved companion diagnostic and an alternative assay kit for assessing homologous recombination deficiency in ovarian cancer

Wehn, A. K., Qiu, P., Lunceford, J., Yarunin, A., Cristescu, R., Liu, L., Roessler, K., Bilke, S., Day, J. R., Timms, K. M., Weichert, W. & Marton, M. J., May 2024, In: Gynecologic Oncology. 184, p. 67-73 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Consent as a compositional act – a framework that provides clarity for the retention and use of data

Rivas Velarde, M. C., Lovis, C., Ienca, M., Samer, C. & Hurst, S., Dec 2024, In: Philosophy, Ethics, and Humanities in Medicine. 19, 1, 2.

Research output: Contribution to journal › Article › peer-review

Open Access

Contribution of VEGF-B-Induced Endocardial Endothelial Cell Lineage in Physiological Versus Pathological Cardiac Hypertrophy

Sultan, I., Ramste, M., Peletier, P., Hemanthakumar, K. A., Ramanujam, D., Tirronen, A., Von Wright, Y., Antila, S., Saharinen, P., Eklund, L., Mervaala, E., Yla-Herttuala, S., Engelhardt, S., Kivela, R. & Alitalo, K., 24 May 2024, In: Circulation Research. 134, 11, p. 1465-1482 18 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Cytokine Response of Natural Killer Cells to Hepatitis B Virus Infection Depends on Monocyte Co-Stimulation

Kupke, P., Brucker, J., Wettengel, J. M., Protzer, U., Wenzel, J. J., Schlitt, H. J., Geissler, E. K. & Werner, J. M., May 2024, In: Viruses. 16, 5, 741.

Research output: Contribution to journal › Article › peer-review

Open Access

Deep brain stimulation and suicide attempts in treatment-resistant patients: a case report and neuroethical analysis

D’Imperio, A. & Ienca, M., 2024, In: Frontiers in Psychiatry. 15, 1398777.

Research output: Contribution to journal › Article › peer-review

Open Access

Digitalisierung der histopathologischen Routinediagnostik: Dos and Don’ts!

Translated title of the contribution: Digital transformation of a routine histopathology lab: Dos and don’ts!Iwuajoku, V., Haas, A., Ekici, K., Khan, M. Z., Stögbauer, F., Steiger, K., Mogler, C. & Schüffler, P. J., Mar 2024, In: Pathologie. 45, 2, p. 98-105 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Discovery of a monoclonal, high-affinity CD8⁺ T-cell clone following natural hepatitis C virus infection

Cai, C., Keoshkerian, E., Wing, K., Samir, J., Effenberger, M., Schober, K., Bull, R. A., Lloyd, A. R., Busch, D. H. & Luciani, F., Aug 2024, In: Immunology and Cell Biology. 102, 7, p. 630-641 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

DNA methylation profiling identifies TBKBP1 as potent amplifier of cytotoxic activity in CMV-specific human CD8⁺ T cells

Yu, Z., Sasidharan-Nair, V., Buchta, T., Bonifacius, A., Khan, F., Pietzsch, B., Ahmadi, H., Beckstette, M., Niemz, J., Hilgendorf, P., Mausberg, P., Keller, A., Falk, C., Busch, D. H., Schober, K., Cicin-Sain, L., Müller, F., Brinkmann, M. M., Eiz-Vesper, B. & Floess, S. & 1 others, Huehn, J., Sep 2024, In: PLoS Pathogens. 20, 9 September, e1012581.

Research output: Contribution to journal › Article › peer-review

Open Access

Dynamic monitoring of viral gene expression reveals rapid antiviral effects of CD8 T cells recognizing the HCMV-pp65 antigen

Khan, F., Müller, T. R., Kasmapour, B., Ynga-Durand, M. A., Eiz-Vesper, B., von Einem, J., Busch, D. H. & Cicin-Sain, L., 2024, In: Frontiers in Immunology. 15, 1439184.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Embedded Ethics and the “Soft Impacts” of Technology

Tigard, D. W., Braun, M., Breuer, S., Fiske, A., McLennan, S. & Buyx, A., Dec 2024, In: Bulletin of Science, Technology and Society. 44, 3-4, p. 73-83 11 p.

Research output: Contribution to journal › Article › peer-review

Epidemiology of Renal Replacement Therapy for Critically Ill Patients across Seven Health Jurisdictions

Ziegler, J., Morley, K., Pilcher, D., Bellomo, R., Soares, M., Salluh, J. I. F., Borges, L. P., Bagshaw, S. M., Hudson, D., Christiansen, C. F., Heide-Jorgensen, U., Lone, N. I., Buyx, A., McLennan, S., Celi, L. A. & Rush, B., 1 Oct 2024, In: American Journal of Nephrology. 55, 5, p. 539-550 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

European guidelines for the diagnosis and treatment of pancreatic exocrine insufficiency: UEG, EPC, EDS, ESPEN, ESPGHAN, ESDO, and ESPCG evidence-based recommendations

European PEI Multidisciplinary Group, 2024, (Accepted/In press) In: United European Gastroenterology Journal.

Research output: Contribution to journal › Article › peer-review

Open Access

Evaluation of novel Epstein-Barr virus-derived antigen formulations for monitoring virus-specific T cells in pediatric patients with infectious mononucleosis

Fischer, F., Mücke, J., Werny, L., Gerrer, K., Mihatsch, L., Zehetmaier, S., Riedel, I., Geisperger, J., Bodenhausen, M., Schulte-Hillen, L., Hoffmann, D., Protzer, U., Mautner, J., Behrends, U., Bauer, T. & Körber, N., Dec 2024, In: Virology Journal. 21, 1, 139.

Research output: Contribution to journal › Article › peer-review

Open Access

Evaluation of the effectiveness of a nationwide precision medicine program for patients with advanced non-small cell lung cancer in Germany: a historical cohort analysis

Kästner, A., Kron, A., van den Berg, N., Moon, K., Scheffler, M., Schillinger, G., Pelusi, N., Hartmann, N., Rieke, D. T., Stephan-Falkenau, S., Schuler, M., Wermke, M., Weichert, W., Klauschen, F., Haller, F., Hummel, H. D., Sebastian, M., Gattenlöhner, S., Bokemeyer, C. & Esposito, I. & 5 others, Jakobs, F., von Kalle, C., Büttner, R., Wolf, J. & Hoffmann, W., Jan 2024, In: The Lancet Regional Health - Europe. 36, 100788.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Gastric cancer prevention by community eradication of Helicobacter pylori: a cluster-randomized controlled trial

Pan, K. F., Li, W. Q., Zhang, L., Liu, W. D., Ma, J. L., Zhang, Y., Ulm, K., Wang, J. X., Zhang, L., Bajbouj, M., Zhang, L. F., Li, M., Vieth, M., Quante, M., Wang, L. H., Suchanek, S., Mejías-Luque, R., Xu, H. M., Fan, X. H. & Han, X. & 7 others, Liu, Z. C., Zhou, T., Guan, W. X., Schmid, R. M., Gerhard, M., Classen, M. & You, W. C., Nov 2024, In: Nature Medicine. 30, 11, p. 3250-3260 11 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Genetically-modified, redirected T cells target hepatitis B surface antigen-positive hepatocytes and hepatocellular carcinoma lesions in a clinical setting

Wan, X., Wisskirchen, K., Jin, T., Yang, L., Wang, X., Wu, X., Liu, F., Wu, Y., Ma, C., Pang, Y., Li, Q., Zhang, K., Protzer, U. & Du, S., Oct 2024, In: Clinical and Molecular Hepatology. 30, 4, p. 735-755 21 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

German medical students’ views regarding Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): a cross-sectional survey

Schimmerl, L., Haller, B., Buyx, A. & McLennan, S., Dec 2024, In: Discover Education. 3, 1, 177.

Research output: Contribution to journal › Article › peer-review

Open Access

HBV-related HCC development in mice is STAT3 dependent and indicates an oncogenic effect of HBx

Ringelhan, M., Schuehle, S., van de Klundert, M., Kotsiliti, E., Plissonnier, M. L., Faure-Dupuy, S., Riedl, T., Lange, S., Wisskirchen, K., Thiele, F., Cheng, C. C., Yuan, D., Leone, V., Schmidt, R., Hünergard, J., Geisler, F., Unger, K., Algül, H., Schmid, R. M. & Rad, R. & 4 others, Wedemeyer, H., Levrero, M., Protzer, U. & Heikenwalder, M., Oct 2024, In: JHEP Reports. 6, 10, 101128.

Research output: Contribution to journal › Article › peer-review

Open Access

Hepatitis B Virus Neutralization with DNA Origami Nanoshells

Willner, E. M., Kolbe, F., Momburg, F., Protzer, U. & Dietz, H., 22 May 2024, In: ACS Applied Materials and Interfaces. 16, 20, p. 25836-25842 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Department of Preclinical Medicine

Research output

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