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Chair of Developmental Genetics

Collaborations and top research areas from the last five years

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  • A fin-loop-like structure in GPX4 underlies neuroprotection from ferroptosis

    Lorenz, S. M., Wahida, A., Bostock, M. J., Seibt, T., Santos Dias Mourão, A., Levkina, A., Trümbach, D., Soudy, M., Emler, D., Rothammer, N., Woo, M. S., Sonner, J. K., Novikova, M., Henkelmann, B., Aldrovandi, M., Kaemena, D. F., Mishima, E., Vermonden, P., Zong, Z. & Chen, D. & 53 others, Nakamura, T., Ito, J., Doll, S., Proneth, B., Bürkle, E., Rizzollo, F., Escamilla Ayala, A., Napolitano, V., Kolonko-Adamska, M., Gaussmann, S., Merl-Pham, J., Hauck, S., Pertek, A., Orschmann, T., van San, E., Vanden Berghe, T., Hass, D., Maida, A., Frenz, J. M., Pedrera, L., Dolga, A., Kraiger, M., Hrabé de Angelis, M., Fuchs, H., Ebert, G., Lenberg, J., Friedman, J., Scale, C., Agostinis, P., Zimprich, A., Vogt-Weisenhorn, D., Garrett, L., Hölter, S. M., Wurst, W., Glaab, E., Lewerenz, J., Popper, B., Sieben, C., Steinacker, P., Zischka, H., Garcia-Saez, A. J., Tietze, A., Ramesh, S. K., Ayton, S., Vincendeau, M., Friese, M. A., Wigby, K., Sattler, M., Mann, M., Ingold, I., Jayavelu, A. K., Popowicz, G. M. & Conrad, M., 8 Jan 2026, In: Cell. 189, 1, p. 287-306.e35

    Research output: Contribution to journal › Article › peer-review

    Open Access
    33 Scopus citations

  • TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism

    Feiten, A. F., Dahm, K., Schlepckow, K., van Lengerich, B., Suh, J. H., Reifschneider, A., Wefers, B., Bartos, L. M., Wind-Mark, K., de Weerd, L., Ulas, T., De-Domenico, E., Grundschöttel, P., Paulusch, S., Tast, B., Honda, T., Müller, S. A., Becker, M., Khalin, I. & Ricci, A. & 21 others, Liesz, A., Brunner, B., Krenner, C., Buschmann, K., Nuscher, B., Spieth, L., Junker, N., Berghoff, S. A., Davis, S. S., Neher, J. J., Wurst, W., Plesnila, N., Lewcock, J. W., Simons, M., Lichtenthaler, S. F., Di Paolo, G., Brendel, M., Capell, A., Monroe, K. M., Schultze, J. L. & Haass, C., Dec 2026, In: Nature Communications. 17, 1, 2002.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    15 Scopus citations

  • Erratum: Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology by seeding β-amyloidosis (Immunity (2024) 57(11) (2651–2668.e12), (S1074761324004588), (10.1016/j.immuni.2024.09.014))

    Kaji, S., Berghoff, S. A., Spieth, L., Schlaphoff, L., Sasmita, A. O., Vitale, S., Büschgens, L., Kedia, S., Zirngibl, M., Nazarenko, T., Damkou, A., Hosang, L., Depp, C., Kamp, F., Scholz, P., Ewers, D., Giera, M., Ischebeck, T., Wurst, W. & Wefers, B. & 9 others, Schifferer, M., Willem, M., Nave, K. A., Haass, C., Arzberger, T., Jäkel, S., Wirths, O., Saher, G. & Simons, M., 14 Jan 2025, In: Immunity. 58, 1, p. 263 1 p.

    Research output: Contribution to journal › Comment/debate

    Open Access
    2 Scopus citations
View all 273 Research outputs