Research output per year
Research output per year
- 40 results
Search results
-
2024
A helminth enzyme subverts macrophage-mediated immunity by epigenetic targeting of prostaglandin synthesis
Bohnacker, S., Henkel, F. D. R., Hartung, F., Geerlof, A., Riemer, S., Prodjinotho, U. F., Salah, E. B., Dias Mourão, A. S., Bohn, S., Teder, T., Thomas, D., Gurke, R., Boeckel, C., Ud-Dean, M., König, A. C., Quaranta, A., Alessandrini, F., Lechner, A., Spitzlberger, B. & Kabat, A. M. & 10 others, , Dec 2024, In: Science Immunology. 9, 102, eadl1467.Research output: Contribution to journal › Article › peer-review
Open Access -
Development of an enabling platform biotechnology for the production of proteins
Aschenbrenner, I., Böckler, M., Franke, F., Liebl, K., Catici, D. A. M., Brandl, M., Behnke, J. & Feige, M. J., 1 Jul 2024, In: Biological Chemistry. 405, 7-8, p. 471-483 13 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
2023
A chemical probe unravels the reactive proteome of health-associated catechols
Weigert Muñoz, A., Meighen-Berger, K. M., Hacker, S. M., Feige, M. J. & Sieber, S. A., 22 Jul 2023, In: Chemical Science. 14, 32, p. 8635-8643 9 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Assembly-dependent Structure Formation Shapes Human Interleukin-23 versus Interleukin-12 Secretion
Aschenbrenner, I., Siebenmorgen, T., Lopez, A., Parr, M., Ruckgaber, P., Kerle, A., Rührnößl, F., Catici, D., Haslbeck, M., Frishman, D., Sattler, M., Zacharias, M. & Feige, M. J., 1 Dec 2023, In: Journal of Molecular Biology. 435, 23, 168300.Research output: Contribution to journal › Article › peer-review
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Human interleukin-12α and EBI3 are cytokines with anti-inflammatory functions
Hildenbrand, K., Bohnacker, S., Menon, P. R., Kerle, A., Prodjinotho, U. F., Hartung, F., Strasser, P. C., Catici, D. A. M., Ruhrnosl, F., Haslbeck, M., Schumann, K., Muller, S. I., da Costa, C. P., Esser-Von Bieren, J. & Feige, M. J., Oct 2023, In: Science Advances. 9, 43, eadg6874.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Mechanistic insights into the aggregation pathway of the patient-derived immunoglobulin light chain variable domain protein FOR005
Pradhan, T., Sarkar, R., Meighen-Berger, K. M., Feige, M. J., Zacharias, M. & Reif, B., Dec 2023, In: Nature Communications. 14, 1, 3755.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Modeling of the human interleukin 12:receptor complex allows to engineer attenuated cytokine variants
Liebl, K., Aschenbrenner, I., Schiller, L., Kerle, A., Protzer, U. & Feige, M. J., Oct 2023, In: Molecular Immunology. 162, p. 38-44 7 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
The DNA-binding induced (de)AMPylation activity of a Coxiella burnetii Fic enzyme targets Histone H3
Höpfner, D., Cichy, A., Pogenberg, V., Krisp, C., Mezouar, S., Bach, N. C., Grotheer, J., Zarza, S. M., Martinez, E., Bonazzi, M., Feige, M. J., Sieber, S. A., Schlüter, H. & Itzen, A., Dec 2023, In: Communications Biology. 6, 1, 1124.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
A comprehensive set of ER protein disulfide isomerase family members supports the biogenesis of proinflammatory interleukin 12 family cytokines
Mideksa, Y. G., Aschenbrenner, I., Fux, A., Kaylani, D., Weiß, C. A. M., Nguyen, T. A., Bach, N. C., Lang, K., Sieber, S. A. & Feige, M. J., Dec 2022, In: Journal of Biological Chemistry. 298, 12, 102677.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Intramembrane client recognition potentiates the chaperone functions of calnexin
Bloemeke, N., Meighen-Berger, K., Hitzenberger, M., Bach, N. C., Parr, M., Coelho, J. P. L., Frishman, D., Zacharias, M., Sieber, S. A. & Feige, M. J., 15 Dec 2022, In: EMBO Journal. 41, 24, e110959.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
The human signal peptidase complex acts as a quality control enzyme for membrane proteins
Zanotti, A., Coelho, J. P. L., Kaylani, D., Singh, G., Tauber, M., Hitzenberger, M., Avci, D., Zacharias, M., Russell, R. B., Lemberg, M. K. & Feige, M. J., 2 Dec 2022, In: Science. 378, 6623, p. 996-1000 5 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
2021
Fluorescent palladium(ii) and platinum(ii) NHC/1,2,3-triazole complexes: antiproliferative activity and selectivity against cancer cells
Schlagintweit, J. F., Jakob, C. H. G., Meighen-Berger, K., Gronauer, T. F., Weigert Muñoz, A., Weiß, V., Feige, M. J., Sieber, S. A., Correia, J. D. G. & Kühn, F. E., 14 Feb 2021, In: Dalton Transactions. 50, 6, p. 2158-2166 9 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Quality control of mislocalized and orphan proteins
Kong, K. Y. E., Coelho, J. P. L., Feige, M. J. & Khmelinskii, A., 15 Jun 2021, In: Experimental Cell Research. 403, 2, 112617.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Specificity of AMPylation of the human chaperone BiP is mediated by TPR motifs of FICD
Fauser, J., Gulen, B., Pogenberg, V., Pett, C., Pourjafar-Dehkordi, D., Krisp, C., Höpfner, D., König, G., Schlüter, H., Feige, M. J., Zacharias, M., Hedberg, C. & Itzen, A., 1 Dec 2021, In: Nature Communications. 12, 1, 2426.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
2020
An anti-inflammatory eicosanoid switch mediates the suppression of type-2 inflammation by helminth larval products
de los Reyes Jiménez, M., Lechner, A., Alessandrini, F., Bohnacker, S., Schindela, S., Trompette, A., Haimerl, P., Thomas, D., Henkel, F., Mourão, A., Geerlof, A., da Costa, C. P., Chaker, A. M., Brüne, B., Nüsing, R., Jakobsson, P. J., Nockher, W. A., Feige, M. J., Haslbeck, M. & Ohnmacht, C. & 5 others, , 22 Apr 2020, In: Science Translational Medicine. 12, 540, eaay0605.Research output: Contribution to journal › Article › peer-review
Open Access38 Scopus citations -
Glycosaminoglycans bind human IL-27 and regulate its activity
Cavé, M. C., Maillard, S., Hildenbrand, K., Mamelonet, C., Feige, M. J. & Devergne, O., 1 Oct 2020, In: European Journal of Immunology. 50, 10, p. 1484-1499 16 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Influence of glycosylation on IL-12 family cytokine biogenesis and function
Bohnacker, S., Hildenbrand, K., Aschenbrenner, I., Müller, S. I., Bieren, J. E. V. & Feige, M. J., Oct 2020, In: Molecular Immunology. 126, p. 120-128 9 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Site-Specific Protein Labeling with Fluorophores as a Tool To Monitor Protein Turnover
Mideksa, Y. G., Fottner, M., Braus, S., Weiß, C. A. M., Nguyen, T. A., Meier, S., Lang, K. & Feige, M. J., 1 Jul 2020, In: ChemBioChem. 21, 13, p. 1861-1867 7 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Structural Insight into IAPP-Derived Amyloid Inhibitors and Their Mechanism of Action
Niu, Z., Prade, E., Malideli, E., Hille, K., Jussupow, A., Mideksa, Y. G., Yan, L. M., Qian, C., Fleisch, M., Messias, A. C., Sarkar, R., Sattler, M., Lamb, D. C., Feige, M. J., Camilloni, C., Kapurniotu, A. & Reif, B., 27 Mar 2020, In: Angewandte Chemie International Edition in English. 59, 14, p. 5771-5781 11 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
2019
A folding switch regulates interleukin 27 biogenesis and secretion of its α-subunit as a cytokine
Müller, S. I., Friedl, A., Aschenbrenner, I., Bieren, J. E. V., Zacharias, M., Devergne, O. & Feige, M. J., 29 Jan 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 5, p. 1585-1590 6 p.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
A network of chaperones prevents and detects failures in membrane protein lipid bilayer integration
Coelho, J. P. L., Stahl, M., Bloemeke, N., Meighen-Berger, K., Alvira, C. P., Zhang, Z. R., Sieber, S. A. & Feige, M. J., 1 Dec 2019, In: Nature Communications. 10, 1, 672.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
An Interspecies Analysis Reveals Molecular Construction Principles of Interleukin 27
Müller, S. I., Aschenbrenner, I., Zacharias, M. & Feige, M. J., 31 May 2019, In: Journal of Molecular Biology. 431, 12, p. 2383-2393 11 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Genetically Encoded Biotin Analogues: Incorporation and Application in Bacterial and Mammalian Cells
Hohl, A., Mideksa, Y. G., Karan, R., Akal, A., Vogler, M., Groll, M., Rueping, M., Lang, K., Feige, M. J. & Eppinger, J., 15 Jul 2019, In: ChemBioChem. 20, 14, p. 1795-1798 4 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
The molecular basis of chaperone-mediated interleukin 23 assembly control
Meier, S., Bohnacker, S., Klose, C. J., Lopez, A., Choe, C. A., Schmid, P. W. N., Bloemeke, N., Rührnößl, F., Haslbeck, M., Bieren, J. E. V., Sattler, M., Huang, P. S. & Feige, M. J., 1 Dec 2019, In: Nature Communications. 10, 1, 4121.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
2018
Dissipative Self-Assembly of Photoluminescent Silicon Nanocrystals
Grötsch, R. K., Angı, A., Mideksa, Y. G., Wanzke, C., Tena-Solsona, M., Feige, M. J., Rieger, B. & Boekhoven, J., 26 Oct 2018, In: Angewandte Chemie International Edition in English. 57, 44, p. 14608-14612 5 p.Research output: Contribution to journal › Article › peer-review
74 Scopus citations -
HIAPP forms toxic oligomers in plasma
Rodriguez Camargo, D. C., Garg, D., Buday, K., Franko, A., Rodriguez Camargo, A., Schmidt, F., Cox, S. J., Suladze, S., Haslbeck, M., Mideksa, Y. G., Gemmecker, G., Aichler, M., Mettenleiter, G., Schulz, M., Walch, A. K., Hrabě De Angelis, M., Feige, M. J., Sierra, C. A., Conrad, M. & Tripsianes, K. & 2 others, , 2018, In: Chemical Communications. 54, 43, p. 5426-5429 4 p.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
2017
Assembly-induced folding regulates interleukin 12 biogenesis and secretion
Reitberger, S., Haimerl, P., Aschenbrenner, I., Esser-von Bieren, J. & Feige, M. J., 12 May 2017, In: Journal of Biological Chemistry. 292, 19, p. 8073-8081 9 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
2016
Members of the Hsp70 Family Recognize Distinct Types of Sequences to Execute ER Quality Control
Behnke, J., Mann, M. J., Scruggs, F. L., Feige, M. J. & Hendershot, L. M., 1 Sep 2016, In: Molecular Cell. 63, 5, p. 739-752 14 p.Research output: Contribution to journal › Article › peer-review
Open Access104 Scopus citations -
2015
Dimerization-dependent folding underlies assembly control of the clonotypic αβT cell receptor chains
Feige, M. J., Behnke, J., Mittag, T. & Hendershot, L. M., 30 Oct 2015, In: Journal of Biological Chemistry. 290, 44, p. 26821-26831 11 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
2013
Conformational selection in substrate recognition by Hsp70 chaperones
Marcinowski, M., Rosam, M., Seitz, C., Elferich, J., Behnke, J., Bello, C., Feige, M. J., Becker, C. F. W., Antes, I. & Buchner, J., 8 Feb 2013, In: Journal of Molecular Biology. 425, 3, p. 466-474 9 p.Research output: Contribution to journal › Article › peer-review
39 Scopus citations -
2011
Substrate discrimination of the chaperone BiP by autonomous and cochaperone-regulated conformational transitions
Marcinowski, M., Höller, M., Feige, M. J., Baerend, D., Lamb, D. C. & Buchner, J., Feb 2011, In: Nature Structural and Molecular Biology. 18, 2, p. 150-159 10 p.Research output: Contribution to journal › Article › peer-review
144 Scopus citations -
2010
Dissecting the alternatively folded state of the antibody fab fragment
Feige, M. J., Simpson, E. R., Herold, E. M., Bepperling, A., Heger, K. & Buchner, J., Jun 2010, In: Journal of Molecular Biology. 399, 5, p. 719-730 12 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Regions outside the α-crystallin domain of the small heat shock protein Hsp26 are required for its dimerization
Chen, J., Feige, M. J., Franzmann, T. M., Bepperling, A. & Buchner, J., Apr 2010, In: Journal of Molecular Biology. 398, 1, p. 122-131 10 p.Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
Structural and Mechanical Hierarchies in the α-Crystallin Domain Dimer of the Hyperthermophilic Small Heat Shock Protein Hsp16.5
Bertz, M., Chen, J., Feige, M. J., Franzmann, T. M., Buchner, J. & Rief, M., Jul 2010, In: Journal of Molecular Biology. 400, 5, p. 1046-1056 11 p.Research output: Contribution to journal › Article › peer-review
19 Scopus citations -
2009
An Unfolded CH1 Domain Controls the Assembly and Secretion of IgG Antibodies
Feige, M. J., Groscurth, S., Marcinowski, M., Shimizu, Y., Kessler, H., Hendershot, L. M. & Buchner, J., 12 Jun 2009, In: Molecular Cell. 34, 5, p. 569-579 11 p.Research output: Contribution to journal › Article › peer-review
Open Access195 Scopus citations -
Structure of the Murine Unglycosylated IgG1 Fc Fragment
Feige, M. J., Nath, S., Catharino, S. R., Weinfurtner, D., Steinbacher, S. & Buchner, J., 21 Aug 2009, In: Journal of Molecular Biology. 391, 3, p. 599-608 10 p.Research output: Contribution to journal › Article › peer-review
80 Scopus citations -
2008
Rate of Loop Formation in Peptides: A Simulation Study
Feige, M. J. & Paci, E., 3 Oct 2008, In: Journal of Molecular Biology. 382, 2, p. 556-565 10 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
The structure of a folding intermediate provides insight into differences in immunoglobulin amyloidogenicity
Feige, M. J., Groscurth, S., Marcinowski, M., Zu, T. Y., Truffault, V., Paci, E., Kessler, H. & Buchner, J., 9 Sep 2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 36, p. 13373-13378 6 p.Research output: Contribution to journal › Article › peer-review
Open Access40 Scopus citations -
2007
Influence of the Internal Disulfide Bridge on the Folding Pathway of the CL Antibody Domain
Feige, M. J., Hagn, F., Esser, J., Kessler, H. & Buchner, J., 26 Jan 2007, In: Journal of Molecular Biology. 365, 4, p. 1232-1244 13 p.Research output: Contribution to journal › Article › peer-review
38 Scopus citations -
2004
Folding mechanism of the CH2 antibody domain
Feige, M. J., Walter, S. & Buchner, J., 12 Nov 2004, In: Journal of Molecular Biology. 344, 1, p. 107-118 12 p.Research output: Contribution to journal › Article › peer-review
69 Scopus citations