Associate Professorship of Cardiovascular Biology

2025

Contribution of hypoxia-inducible factor 1alpha to pathogenesis of sarcomeric hypertrophic cardiomyopathy

Raj Murthi, S., Petry, A., Shashikadze, B., Stöckl, J. B., Schmid, M., Santamaria, G., Klingel, K., Kračun, D., Chen, X., Bauer, S., Schmitt, J. P., Flenkenthaler, F., Gorham, J., Toepfer, C. N., Potěšil, D., Hruška, P., Zdráhal, Z., Mayer, Z., Klop, M. & Lehmann, L. & 11 others, Qin, Y., Papanakli, L., Spielmann, N., Moretti, A., Fröhlich, T., Ewert, P., Holdenrieder, S., Seidman, J. G., Seidman, C. E., Görlach, A. & Wolf, C. M., Dec 2025, In: Scientific Reports. 15, 1, 2132.

Research output: Contribution to journal › Article › peer-review

Open Access

Reactive oxygen species in tendon injury and repair

Kračun, D., Görlach, A., Snedeker, J. G. & Buschmann, J., Apr 2025, In: Redox Biology. 81, 103568.

Research output: Contribution to journal › Review article › peer-review

Open Access

2024

Inflammation and Fibrosis in Progeria: Organ-Specific Responses in an HGPS Mouse Model

Krüger, P., Schroll, M., Fenzl, F., Lederer, E. M., Hartinger, R., Arnold, R., Cagla Togan, D., Guo, R., Liu, S., Petry, A., Görlach, A. & Djabali, K., Sep 2024, In: International Journal of Molecular Sciences. 25, 17, 9323.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

2022

Cell cycle defects underlie childhood-onset cardiomyopathy associated with Noonan syndrome

Meier, A. B., Raj Murthi, S., Rawat, H., Toepfer, C. N., Santamaria, G., Schmid, M., Mastantuono, E., Schwarzmayr, T., Berutti, R., Cleuziou, J., Ewert, P., Görlach, A., Klingel, K., Laugwitz, K. L., Seidman, C. E., Seidman, J. G., Moretti, A. & Wolf, C. M., 21 Jan 2022, In: iScience. 25, 1, 103596.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy

IMPC Consortium & Genomics England Research Consortium, Feb 2022, In: Nature Cardiovascular Research. 1, 2, p. 157-173 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

MondoA drives malignancy in B-ALL through enhanced adaptation to metabolic stress

Sipol, A., Hameister, E., Xue, B., Hofstetter, J., Barenboim, M., Öllinger, R., Jain, G., Prexler, C., Rubio, R. A., Baldauf, M. C., Franchina, D. G., Petry, A., Schmäh, J., Thiel, U., Görlach, A., Cario, G., Brenner, D., Richter, G. H. S., Grünewald, T. G. P. & Rad, R. & 4 others, Wolf, E., Ruland, J., Sorensen, P. H. & Burdach, S. E. G., 24 Feb 2022, In: Blood. 139, 8, p. 1184-1197 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Neutrophil “plucking” on megakaryocytes drives platelet production and boosts cardiovascular disease

Petzold, T., Zhang, Z., Ballesteros, I., Saleh, I., Polzin, A., Thienel, M., Liu, L., Ul Ain, Q., Ehreiser, V., Weber, C., Kilani, B., Mertsch, P., Götschke, J., Cremer, S., Fu, W., Lorenz, M., Ishikawa-Ankerhold, H., Raatz, E., El-Nemr, S. & Görlach, A. & 12 others, Marhuenda, E., Stark, K., Pircher, J., Stegner, D., Gieger, C., Schmidt-Supprian, M., Gaertner, F., Almendros, I., Kelm, M., Schulz, C., Hidalgo, A. & Massberg, S., 13 Dec 2022, In: Immunity. 55, 12, p. 2285-2299.e7

Research output: Contribution to journal › Article › peer-review

Open Access

47 Scopus citations

Publisher Correction: Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy (Nature Cardiovascular Research, (2022), 1, 2, (157-173), 10.1038/s44161-022-00018-8)

IMPC Consortium & Genomics England Research Consortium, May 2022, In: Nature Cardiovascular Research. 1, 5, p. 529-531 3 p.

Research output: Contribution to journal › Comment/debate

Open Access

3 Scopus citations

2021

Compound mutation in cardiac sarcomere proteins is associated with increased risk for major arrhythmic events in pediatric onset hypertrophic cardiomyopathy

Pollmann, K., Kaltenecker, E., Schleihauf, J., Ewert, P., Görlach, A. & Wolf, C. M., 1 Nov 2021, In: Journal of Clinical Medicine. 10, 22, 5256.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Molecular signaling pathways in right ventricular impairment of adult patients after tetralogy of Fallot repair

Pollmann, K., Murthi, S. R., Kračun, D., Schwarzmayr, T., Petry, A., Cleuziou, J., Hörer, J., Klop, M., Ewert, P., Görlach, A. & Wolf, C. M., Dec 2021, In: Cardiovascular Diagnosis and Therapy. 11, 6, p. 1295-1309 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

NADPH-Oxidasen und HIF: zentrale Elemente der Redoxhomöostase

Translated title of the contribution: NADPH oxidases and HIF: Central elements of redox homeostasisPetry, A. & Görlach, A., Mar 2021, In: BioSpektrum. 27, 2, p. 142-145 4 p.

Research output: Contribution to journal › Comment/debate

Open Access

2020

NADPH oxidases and HIF1 promote cardiac dysfunction and pulmonary hypertension in response to glucocorticoid excess

Kračun, D., Klop, M., Knirsch, A., Petry, A., Kanchev, I., Chalupsky, K., Wolf, C. M. & Görlach, A., Jul 2020, In: Redox Biology. 34, 101536.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

2019

Cross talk between p22phox and ATF4 in the endothelial unfolded protein response

Petry, A., Zhang, Z., Trautz, B., Rieß, F. & Görlach, A., 1 Jan 2019, In: Antioxidants and Redox Signaling. 30, 1, p. 40-55 16 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

HIF-1α is required for development of the sympathetic nervous system

Bohuslavova, R., Cerychova, R., Papousek, F., Olejnickova, V., Bartos, M., Görlach, A., Kolar, F., Sedmera, D., Semenza, G. L. & Pavlinkova, G., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 27, p. 13414-13423 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

56 Scopus citations

In vivo assessment of heart function under chronic hypoxic stress with volumetric optoacoustic tomography

Ivankovic, I., Lin, H. C. A., Deán-Ben, X. L., Zhang, Z., Trautz, B., Gorlach, A. & Razansky, D., 2019, Photons Plus Ultrasound: Imaging and Sensing 2019. Oraevsky, A. A. & Wang, L. V. (eds.). SPIE, 108782B. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10878).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Open Access

Regulation of NADPH oxidases by G protein-coupled receptors

Petry, A. & Görlach, A., 1 Jan 2019, In: Antioxidants and Redox Signaling. 30, 1, p. 74-94 21 p.

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Stabilization of p22phox by Hypoxia Promotes Pulmonary Hypertension

Zhang, Z., Trautz, B., Kračun, D., Vogel, F., Weitnauer, M., Hochkogler, K., Petry, A. & Görlach, A., 1 Jan 2019, In: Antioxidants and Redox Signaling. 30, 1, p. 56-73 18 p.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Volumetric optoacoustic tomography enables non-invasive in vivo characterization of impaired heart function in hypoxic conditions

Ivankovic, I., Deán-Ben, X. L., Lin, H. C. A., Zhang, Z., Trautz, B., Petry, A., Görlach, A. & Razansky, D., 1 Dec 2019, In: Scientific Reports. 9, 1, 8369.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

2018

Corrigendum to “European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)” (Redox Biol. (2017) 13 (94–162)(S2213231717303373)(10.1016/j.redox.2017.05.007))

Egea, J., Fabregat, I., Frapart, Y. M., Ghezzi, P., Görlach, A., Kietzmann, T., Kubaichuk, K., Knaus, U. G., Lopez, M. G., Olaso-Gonzalez, G., Petry, A., Schulz, R., Vina, J., Winyard, P., Abbas, K., Ademowo, O. S., Afonso, C. B., Andreadou, I., Antelmann, H. & Antunes, F. & 131 others, Aslan, M., Bachschmid, M. M., Barbosa, R. M., Belousov, V., Berndt, C., Bernlohr, D., Bertrán, E., Bindoli, A., Bottari, S. P., Brito, P. M., Carrara, G., Casas, A. I., Chatzi, A., Chondrogianni, N., Conrad, M., Cooke, M. S., Costa, J. G., Cuadrado, A., My-Chan Dang, P., De Smet, B., Debelec-Butuner, B., Dias, I. H. K., Dunn, J. D., Edson, A. J., El Assar, M., El-Benna, J., Ferdinandy, P., Fernandes, A. S., Fladmark, K. E., Förstermann, U., Giniatullin, R., Giricz, Z., Görbe, A., Griffiths, H., Hampl, V., Hanf, A., Herget, J., Hernansanz-Agustín, P., Hillion, M., Huang, J., Ilikay, S., Jansen-Dürr, P., Jaquet, V., Joles, J. A., Kalyanaraman, B., Kaminskyy, D., Karbaschi, M., Kleanthous, M., Klotz, L. O., Korac, B., Korkmaz, K. S., Koziel, R., Kračun, D., Krause, K. H., Křen, V., Krieg, T., Laranjinha, J., Lazou, A., Li, H., Martínez-Ruiz, A., Matsui, R., McBean, G. J., Meredith, S. P., Messens, J., Miguel, V., Mikhed, Y., Milisav, I., Milković, L., Miranda-Vizuete, A., Mojović, M., Monsalve, M., Mouthuy, P. A., Mulvey, J., Münzel, T., Muzykantov, V., Nguyen, I. T. N., Oelze, M., Oliveira, N. G., Palmeira, C. M., Papaevgeniou, N., Pavićević, A., Pedre, B., Peyrot, F., Phylactides, M., Pircalabioru, G. G., Pitt, A. R., Poulsen, H. E., Prieto, I., Rigobello, M. P., Robledinos-Antón, N., Rodríguez-Mañas, L., Rolo, A. P., Rousset, F., Ruskovska, T., Saraiva, N., Sasson, S., Schröder, K., Semen, K., Seredenina, T., Shakirzyanova, A., Smith, G. L., Soldati, T., Sousa, B. C., Spickett, C. M., Stancic, A., Stasia, M. J., Steinbrenner, H., Stepanić, V., Steven, S., Tokatlidis, K., Tuncay, E., Turan, B., Ursini, F., Vacek, J., Vajnerova, O., Valentová, K., Van Breusegem, F., Varisli, L., Veal, E. A., Yalçın, A. S., Yelisyeyeva, O., Žarković, N., Zatloukalová, M., Zielonka, J., Touyz, R. M., Papapetropoulos, A., Grune, T., Lamas, S., Schmidt, H. H. H. W., Di Lisa, F. & Daiber, A., Apr 2018, In: Redox Biology. 14, p. 694-696 3 p.

Research output: Contribution to journal › Comment/debate

Open Access

11 Scopus citations

2017

Circular RNA maps paving the road to biomarker development?

Görlach, A. & Holdenrieder, S., 1 Nov 2017, In: Journal of Molecular Medicine. 95, 11, p. 1137-1141 5 p.

Research output: Contribution to journal › Editorial

Open Access

7 Scopus citations

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

Egea, J., Fabregat, I., Frapart, Y. M., Ghezzi, P., Görlach, A., Kietzmann, T., Kubaichuk, K., Knaus, U. G., Lopez, M. G., Olaso-Gonzalez, G., Petry, A., Schulz, R., Vina, J., Winyard, P., Abbas, K., Ademowo, O. S., Afonso, C. B., Andreadou, I., Antelmann, H. & Antunes, F. & 131 others, Aslan, M., Bachschmid, M. M., Barbosa, R. M., Belousov, V., Berndt, C., Bernlohr, D., Bertrán, E., Bindoli, A., Bottari, S. P., Brito, P. M., Carrara, G., Casas, A. I., Chatzi, A., Chondrogianni, N., Conrad, M., Cooke, M. S., Costa, J. G., Cuadrado, A., My-Chan Dang, P., De Smet, B., Debelec-Butuner, B., Dias, I. H. K., Dunn, J. D., Edson, A. J., El Assar, M., El-Benna, J., Ferdinandy, P., Fernandes, A. S., Fladmark, K. E., Förstermann, U., Giniatullin, R., Giricz, Z., Görbe, A., Griffiths, H., Hampl, V., Hanf, A., Herget, J., Hernansanz-Agustín, P., Hillion, M., Huang, J., Ilikay, S., Jansen-Dürr, P., Jaquet, V., Joles, J. A., Kalyanaraman, B., Kaminskyy, D., Karbaschi, M., Kleanthous, M., Klotz, L. O., Korac, B., Korkmaz, K. S., Koziel, R., Kračun, D., Krause, K. H., Křen, V., Krieg, T., Laranjinha, J., Lazou, A., Li, H., Martínez-Ruiz, A., Matsui, R., McBean, G. J., Meredith, S. P., Messens, J., Miguel, V., Mikhed, Y., Milisav, I., Milković, L., Miranda-Vizuete, A., Mojović, M., Monsalve, M., Mouthuy, P. A., Mulvey, J., Münzel, T., Muzykantov, V., Nguyen, I. T. N., Oelze, M., Oliveira, N. G., Palmeira, C. M., Papaevgeniou, N., Pavićević, A., Pedre, B., Peyrot, F., Phylactides, M., Pircalabioru, G. G., Pitt, A. R., Poulsen, H. E., Prieto, I., Rigobello, M. P., Robledinos-Antón, N., Rodríguez-Mañas, L., Rolo, A. P., Rousset, F., Ruskovska, T., Saraiva, N., Sasson, S., Schröder, K., Semen, K., Seredenina, T., Shakirzyanova, A., Smith, G. L., Soldati, T., Sousa, B. C., Spickett, C. M., Stancic, A., Stasia, M. J., Steinbrenner, H., Stepanić, V., Steven, S., Tokatlidis, K., Tuncay, E., Turan, B., Ursini, F., Vacek, J., Vajnerova, O., Valentová, K., Van Breusegem, F., Varisli, L., Veal, E. A., Yalçın, A. S., Yelisyeyeva, O., Žarković, N., Zatloukalová, M., Zielonka, J., Touyz, R. M., Papapetropoulos, A., Grune, T., Lamas, S., Schmidt, H. H. H. W., Di Lisa, F. & Daiber, A., Oct 2017, In: Redox Biology. 13, p. 94-162 69 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

263 Scopus citations

Immunoproteasome subunit ß5i/LMP7-deficiency in atherosclerosis

Hewing, B., Ludwig, A., Dan, C., Pötzsch, M., Hannemann, C., Petry, A., Lauer, D., Görlach, A., Kaschina, E., Müller, D. N., Baumann, G., Stangl, V., Stangl, K. & Wilck, N., 1 Dec 2017, In: Scientific Reports. 7, 1, 13342.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

Prolyl-hydroxylase inhibition induces SDF-1 associated with increased CXCR4+/CD11b+ subpopulations and cardiac repair

Ghadge, S. K., Messner, M., Van Pham, T., Doppelhammer, M., Petry, A., Görlach, A., Husse, B., Franz, W. M. & Zaruba, M. M., 1 Aug 2017, In: Journal of Molecular Medicine. 95, 8, p. 825-837 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

The epigenetic landscape related to reactive oxygen species formation in the cardiovascular system

Kietzmann, T., Petry, A., Shvetsova, A., Gerhold, J. M. & Görlach, A., 2017, In: British Journal of Pharmacology. 174, 12, p. 1533-1554 22 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

196 Scopus citations

2016

Differential transcriptional regulation of hypoxia-inducible factor-1α by arsenite under normoxia and hypoxia: involvement of Nrf2

al Taleb, Z., Petry, A., Chi, T. F., Mennerich, D., Görlach, A., Dimova, E. Y. & Kietzmann, T., 1 Oct 2016, In: Journal of Molecular Medicine. 94, 10, p. 1153-1166 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

Transit of H₂O₂ across the endoplasmic reticulum membrane is not sluggish

Appenzeller-Herzog, C., Bánhegyi, G., Bogeski, I., Davies, K. J. A., Delaunay-Moisan, A., Forman, H. J., Görlach, A., Kietzmann, T., Laurindo, F., Margittai, E., Meyer, A. J., Riemer, J., Rützler, M., Simmen, T., Sitia, R., Toledano, M. B. & Touw, I. P., 1 May 2016, In: Free Radical Biology and Medicine. 94, p. 157-160 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

52 Scopus citations

2015

Calcium and ROS: A mutual interplay

Görlach, A., Bertram, K., Hudecova, S. & Krizanova, O., 1 Dec 2015, In: Redox Biology. 6, p. 260-271 12 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

1178 Scopus citations

Deficiency of HIF1α in Antigen-Presenting Cells Aggravates Atherosclerosis and Type 1 T-Helper Cell Responses in Mice

Chaudhari, S. M., Sluimer, J. C., Koch, M., Theelen, T. L., Manthey, H. D., Busch, M., Caballero-Franco, C., Vogel, F., Cochain, C., Pelisek, J., Daemen, M. J., Lutz, M. B., Görlach, A., Kissler, S., Hermanns, H. M. & Zernecke, A., 1 Nov 2015, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 35, 11, p. 2316-2325 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

45 Scopus citations

Folic Acid Promotes Recycling of Tetrahydrobiopterin and Protects Against Hypoxia-Induced Pulmonary Hypertension by Recoupling Endothelial Nitric Oxide Synthase

Chalupsky, K., Kračun, D., Kanchev, I., Bertram, K. & Görlach, A., 10 Nov 2015, In: Antioxidants and Redox Signaling. 23, 14, p. 1076-1091 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

69 Scopus citations

Mitochondrial Dysfunction Due to Lack of Manganese Superoxide Dismutase Promotes Hepatocarcinogenesis

Konzack, A., Jakupovic, M., Kubaichuk, K., Görlach, A., Dombrowski, F., Miinalainen, I., Sormunen, R. & Kietzmann, T., 10 Nov 2015, In: Antioxidants and Redox Signaling. 23, 14, p. 1059-1075 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

NOX1 supports the metabolic remodeling of HepG2 cells

Bertram, K., Valcu, C. M., Weitnauer, M., Linne, U. & Görlach, A., 25 Mar 2015, In: PLoS ONE. 10, 3, e0122002.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Reactive oxygen species, nutrition, hypoxia and diseases: Problems solved?

Görlach, A., Dimova, E. Y., Petry, A., Martínez-Ruiz, A., Hernansanz-Agustín, P., Rolo, A. P., Palmeira, C. M. & Kietzmann, T., 1 Dec 2015, In: Redox Biology. 6, p. 372-385 14 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

291 Scopus citations

Redox regulation of genome stability by effects on gene expression, epigenetic pathways and DNA damage/repair

Mikhed, Y., Görlach, A., Knaus, U. G. & Daiber, A., 1 Aug 2015, In: Redox Biology. 5, p. 275-289 15 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

142 Scopus citations

Superoxide-generating Nox5α is functionally required for the human T-cell leukemia virus type 1-induced cell transformation phenotype

Shigemura, T., Shiohara, M., Kato, M., Furuta, S., Kaneda, K., Morishita, K., Hasegawa, H., Fujii, M., Gorlach, A., Koike, K. & Kamata, T., 2015, In: Journal of Virology. 89, 17, p. 9080-9089 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: The METOXIA consortium

Pettersen, E. O., Ebbesen, P., Gieling, R. G., Williams, K. J., Dubois, L., Lambin, P., Ward, C., Meehan, J., Kunkler, I. H., Langdon, S. P., Ree, A. H., Flatmark, K., Lyng, H., Calzada, M. J., Peso, L. D., Landazuri, M. O., Görlach, A., Flamm, H., Kieninger, J. & Urban, G. & 27 others, Weltin, A., Singleton, D. C., Haider, S., Buffa, F. M., Harris, A. L., Scozzafava, A., Supuran, C. T., Moser, I., Jobst, G., Busk, M., Toustrup, K., Overgaard, J., Alsner, J., Pouyssegur, J., Chiche, J., Mazure, N., Marchiq, I., Parks, S., Ahmed, A., Ashcroft, M., Pastorekova, S., Cao, Y., Rouschop, K. M., Wouters, B. G., Koritzinsky, M., Mujcic, H. & Cojocari, D., 3 Sep 2015, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 30, 5, p. 689-721 33 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

99 Scopus citations

2014

The β3-integrin binding protein β3-endonexin is a novel negative regulator of hypoxia-inducible factor-1

Kračun, D., Rieß, F., Kanchev, I., Gawaz, M. & Görlach, A., 1 May 2014, In: Antioxidants and Redox Signaling. 20, 13, p. 1964-1976 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

2013

The role of nitric oxide radicals in removal of hyper-radiosensitivity by priming irradiation

Edin, N. J., Sandvik, J. A., Vollan, H. S., Reger, K., Görlach, A. & Pettersen, E. O., Nov 2013, In: Journal of Radiation Research. 54, 6, p. 1015-1028 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

2012

Accounting for biological variation in differential display two-dimensional electrophoresis experiments

Valcu, C. M., Reger, K., Ebner, J. & Görlach, A., 27 Jun 2012, In: Journal of Proteomics. 75, 12, p. 3585-3591 7 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

GSK-3β regulates cell growth, migration, and angiogenesis via Fbw7 and USP28-dependent degradation of HIF-1α

Flügel, D., Görlach, A. & Kietzmann, T., 2 Feb 2012, In: Blood. 119, 5, p. 1292-1301 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

168 Scopus citations

Inhibition of endothelial nitric oxyde synthase increases capillary formation via rac1-dependent induction of hypoxia-inducible factor-1α and plasminogen activator inhibitor-1

Petry, A., Belaiba, R. S., Weitnauer, M. & Görlach, A., Sep 2012, In: Thrombosis and Haemostasis. 108, 5, p. 849-862 14 p.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

NADPH oxidase is internalized by clathrin-coated pits and localizes to a Rab27A/B GTPase-regulated secretory compartment in activated macrophages

Ejlerskov, P., Christensen, D. P., Beyaie, D., Burritt, J. B., Paclet, M. H., Gorlach, A., Van Deurs, B. & Vilhardt, F., 10 Feb 2012, In: Journal of Biological Chemistry. 287, 7, p. 4835-4852 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

31 Scopus citations

NADPH oxidases as a source of oxidative stress and molecular target in ischemia/reperfusion injury

Kleikers, P. W. M., Wingler, K., Hermans, J. J. R., Diebold, I., Altenhöfer, S., Radermacher, K. A., Janssen, B., Görlach, A. & Schmidt, H. H. H. W., Dec 2012, In: Journal of Molecular Medicine. 90, 12, p. 1391-1406 16 p.

Research output: Contribution to journal › Review article › peer-review

146 Scopus citations

STEAP1 is associated with the invasive and oxidative stress phenotype of ewing tumors

Grunewald, T. G. P., Diebold, I., Esposito, I., Plehm, S., Hauer, K., Thiel, U., Da Silva-Buttkus, P., Neff, F., Unland, R., Müller-Tidow, C., Zobywalski, C., Lohrig, K., Lewandrowski, U., Sickmann, A., Da Costa, O. P., Görlach, A., Cossarizza, A., Butt, E., Richter, G. H. S. & Burdach, S., Jan 2012, In: Molecular Cancer Research. 10, 1, p. 52-65 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

110 Scopus citations

The HIF1 target gene NOX2 promotes angiogenesis through urotensin-II

Diebold, I., Petry, A., Sabrane, K., Djordjevic, T., Hess, J. & Görlach, A., 15 Feb 2012, In: Journal of Cell Science. 125, 4, p. 956-964 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

60 Scopus citations

The unfolded protein response controls induction and activation of ADAM17/TACE by severe hypoxia and ER stress

Rzymski, T., Petry, A., Kračun, D., Rie, F., Pike, L., Harris, A. L. & Görlach, A., 2 Aug 2012, In: Oncogene. 31, 31, p. 3621-3634 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

67 Scopus citations

2011

Delineating the angiogenic gene expression profile before pulmonary vascular remodeling in a lamb model of congenital heart disease

Tian, J., Fratz, S., Hou, Y., Lu, Q., Görlach, A., Hess, J., Schreiber, C., Datar, S. A., Oishi, P., Nechtman, J., Podolsky, R., She, J. X., Fineman, J. R. & Black, S. M., Jan 2011, In: Physiological Genomics. 43, 2, p. 87-98 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

NOX4 mediates activation of FoxO3a and matrix metalloproteinase-2 expression by urotensin-II

Diebold, I., Petry, A., Burger, M., Hess, J. & Gor̈lach, A., 15 Nov 2011, In: Molecular Biology of the Cell. 22, 22, p. 4424-4434 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

49 Scopus citations

Tissue inhibitor of metalloproteinases-1-induced scattered liver metastasis is mediated by hypoxia-inducible factor-1 α

Schelter, F., Halbgewachs, B., Bäumler, P., Neu, C., Görlach, A., Schrötzlmair, F. & Krüger, A., Feb 2011, In: Clinical & Experimental Metastasis. 28, 2, p. 91-99 9 p.

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

2010

Heterocyclic indazole derivatives as SGK1 inhibitors, WO2008138448

Lang, F. & Görlach, A., Jan 2010, In: Expert Opinion on Therapeutic Patents. 20, 1, p. 129-135 7 p.

Research output: Contribution to journal › Review article › peer-review

20 Scopus citations

Identification of a survival-independent metastasis-enhancing role of hypoxia-inducible factor-1α with a hypoxia-tolerant tumor cell line

Schelter, F., Gerg, M., Halbgewachs, B., Schaten, S., Görlach, A., Schrötzlmair, F. & Krüger, A., 20 Aug 2010, In: Journal of Biological Chemistry. 285, 34, p. 26182-26189 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Associate Professorship of Cardiovascular Biology

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