@inproceedings{26c342ef6bfe4e40b5ea04bc6dd7efaa,
title = "Validation of non-rigid registration using finite element methods",
abstract = "We present a novel validation method for non-rigid registration using a simulation of deformations based on biomechanical modelling of tissue properties. This method is tested on a previously developed non-rigid registration method for dynamic contrast enhanced Magnetic Resonance (MR) mammography image pairs [1]. We have constructed finite element breast models and applied a range of displacements to them, with an emphasis on generating physically plausible deformations which may occur during normal patient scanning procedures. From the finite element method (FEM) solutions, we have generated a set of deformed contrast enhanced images against which we have registered the original dynamic image pairs. The registration results have been successfully validated at all breast tissue locations by comparing the recovered displacements with the biomechanical displacements. The validation method presented in this paper is an important tool to provide biomechanical gold standard deformations for registration error quantification, which may also form the basis to improve and compare different non-rigid registration techniques for a diversity of medical applications.",
author = "Schnabel, {Julia A.} and Christine Tanner and Smith, {Andy D.Castellano} and Leach, {Martin O.} and Carmel Hayes and Andreas Degenhard and Rodney Hose and Hill, {Derek L.G.} and Hawkes, {David J.}",
note = "Publisher Copyright: {\textcopyright} Springer-Verlag Berlin Heidelberg 2001.; 17th International Conference on Information Processing in Medical Imaging, IPMI 2001 ; Conference date: 18-06-2001 Through 22-06-2001",
year = "2001",
doi = "10.1007/3-540-45729-1_34",
language = "English",
series = "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
publisher = "Springer Verlag",
pages = "344--357",
editor = "Insana, {Michael F.} and Leahy, {Richard M.}",
booktitle = "Information Processing in Medical Imaging - 17th International Conference, IPMI 2001, Proceedings",
}