Transmission-reflection optoacoustic ultrasound (TROPUS) imaging of mammary tumors

Berkan Lafci; Elena Merčep; Joaquin L. Herraiz; Xosé Luís Deán-Ben; Daniel Razansky

doi:10.1117/12.2577907

Transmission-reflection optoacoustic ultrasound (TROPUS) imaging of mammary tumors

Berkan Lafci, Elena Merčep, Joaquin L. Herraiz, Xosé Luís Deán-Ben, Daniel Razansky

Publikation: Beitrag in Buch/Bericht/Konferenzband › Konferenzbeitrag › Begutachtung

1 Zitat (Scopus)

Abstract

Ultrasound (US) and optoacoustic (OA) imaging provide complementary information for quantitative analysis of the tumor microenvironment. Herein, we demonstrate the unique capabilities of transmission-reflection optoacoustic ultrasound (TROPUS) for characterizing breast cancer in tumor-bearing mice. For this, 4 different mice featuring orthotopic tumor of different sizes were scanned with a full-ring ultrasound transducer array to simultaneously render pulse-echo US images, speed of sound (SoS) maps and OA images. The tumor size, vascular density and its elastic parameters were further quantified in the images. Our results pave the way toward clinical translation of the hybrid TROPUS imaging for tumor detection and characterization.

Originalsprache	Englisch
Titel	Photons Plus Ultrasound
Untertitel	Imaging and Sensing 2021
Redakteure/-innen	Alexander A. Oraevsky, Lihong V. Wang
Herausgeber (Verlag)	SPIE
ISBN (elektronisch)	9781510641198
DOIs	https://doi.org/10.1117/12.2577907
Publikationsstatus	Veröffentlicht - 2021
Extern publiziert	Ja
Veranstaltung	Photons Plus Ultrasound: Imaging and Sensing 2021 - Virtual, Online, USA/Vereinigte Staaten Dauer: 6 März 2021 → 11 März 2021

Publikationsreihe

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Band	11642
ISSN (Print)	1605-7422

Konferenz

Konferenz	Photons Plus Ultrasound: Imaging and Sensing 2021
Land/Gebiet	USA/Vereinigte Staaten
Ort	Virtual, Online
Zeitraum	6/03/21 → 11/03/21

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Lafci, B., Merčep, E., Herraiz, J. L., Deán-Ben, X. L., & Razansky, D. (2021). Transmission-reflection optoacoustic ultrasound (TROPUS) imaging of mammary tumors. in A. A. Oraevsky, & L. V. Wang (Hrsg.), Photons Plus Ultrasound: Imaging and Sensing 2021 Artikel 116422L (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Band 11642). SPIE. https://doi.org/10.1117/12.2577907

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title = "Transmission-reflection optoacoustic ultrasound (TROPUS) imaging of mammary tumors",

abstract = "Ultrasound (US) and optoacoustic (OA) imaging provide complementary information for quantitative analysis of the tumor microenvironment. Herein, we demonstrate the unique capabilities of transmission-reflection optoacoustic ultrasound (TROPUS) for characterizing breast cancer in tumor-bearing mice. For this, 4 different mice featuring orthotopic tumor of different sizes were scanned with a full-ring ultrasound transducer array to simultaneously render pulse-echo US images, speed of sound (SoS) maps and OA images. The tumor size, vascular density and its elastic parameters were further quantified in the images. Our results pave the way toward clinical translation of the hybrid TROPUS imaging for tumor detection and characterization.",

keywords = "Cancer research, Optoacoustic imaging, Photoacoustics, Preclinical imaging of tumors, Speed of sound imaging, Ultrasound computed tomography",

author = "Berkan Lafci and Elena Mer{\v c}ep and Herraiz, {Joaquin L.} and De{\'a}n-Ben, {Xos{\'e} Lu{\'i}s} and Daniel Razansky",

note = "Publisher Copyright: {\textcopyright} COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.; Photons Plus Ultrasound: Imaging and Sensing 2021 ; Conference date: 06-03-2021 Through 11-03-2021",

year = "2021",

doi = "10.1117/12.2577907",

language = "English",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

publisher = "SPIE",

editor = "Oraevsky, {Alexander A.} and Wang, {Lihong V.}",

booktitle = "Photons Plus Ultrasound",

}

Lafci, B, Merčep, E, Herraiz, JL, Deán-Ben, XL & Razansky, D 2021, Transmission-reflection optoacoustic ultrasound (TROPUS) imaging of mammary tumors. in AA Oraevsky & LV Wang (Hrsg.), Photons Plus Ultrasound: Imaging and Sensing 2021., 116422L, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Bd. 11642, SPIE, Photons Plus Ultrasound: Imaging and Sensing 2021, Virtual, Online, USA/Vereinigte Staaten, 6/03/21. https://doi.org/10.1117/12.2577907

Transmission-reflection optoacoustic ultrasound (TROPUS) imaging of mammary tumors. / Lafci, Berkan; Merčep, Elena; Herraiz, Joaquin L. et al.
Photons Plus Ultrasound: Imaging and Sensing 2021. Hrsg. / Alexander A. Oraevsky; Lihong V. Wang. SPIE, 2021. 116422L (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Band 11642).

Publikation: Beitrag in Buch/Bericht/Konferenzband › Konferenzbeitrag › Begutachtung

TY - GEN

T1 - Transmission-reflection optoacoustic ultrasound (TROPUS) imaging of mammary tumors

AU - Lafci, Berkan

AU - Merčep, Elena

AU - Herraiz, Joaquin L.

AU - Deán-Ben, Xosé Luís

AU - Razansky, Daniel

N1 - Publisher Copyright: © COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.

PY - 2021

Y1 - 2021

N2 - Ultrasound (US) and optoacoustic (OA) imaging provide complementary information for quantitative analysis of the tumor microenvironment. Herein, we demonstrate the unique capabilities of transmission-reflection optoacoustic ultrasound (TROPUS) for characterizing breast cancer in tumor-bearing mice. For this, 4 different mice featuring orthotopic tumor of different sizes were scanned with a full-ring ultrasound transducer array to simultaneously render pulse-echo US images, speed of sound (SoS) maps and OA images. The tumor size, vascular density and its elastic parameters were further quantified in the images. Our results pave the way toward clinical translation of the hybrid TROPUS imaging for tumor detection and characterization.

AB - Ultrasound (US) and optoacoustic (OA) imaging provide complementary information for quantitative analysis of the tumor microenvironment. Herein, we demonstrate the unique capabilities of transmission-reflection optoacoustic ultrasound (TROPUS) for characterizing breast cancer in tumor-bearing mice. For this, 4 different mice featuring orthotopic tumor of different sizes were scanned with a full-ring ultrasound transducer array to simultaneously render pulse-echo US images, speed of sound (SoS) maps and OA images. The tumor size, vascular density and its elastic parameters were further quantified in the images. Our results pave the way toward clinical translation of the hybrid TROPUS imaging for tumor detection and characterization.

KW - Cancer research

KW - Optoacoustic imaging

KW - Photoacoustics

KW - Preclinical imaging of tumors

KW - Speed of sound imaging

KW - Ultrasound computed tomography

UR - http://www.scopus.com/inward/record.url?scp=85109103588&partnerID=8YFLogxK

U2 - 10.1117/12.2577907

DO - 10.1117/12.2577907

M3 - Conference contribution

AN - SCOPUS:85109103588

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Photons Plus Ultrasound

A2 - Oraevsky, Alexander A.

A2 - Wang, Lihong V.

PB - SPIE

T2 - Photons Plus Ultrasound: Imaging and Sensing 2021

Y2 - 6 March 2021 through 11 March 2021

ER -

Transmission-reflection optoacoustic ultrasound (TROPUS) imaging of mammary tumors

Abstract

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