Transmicron: Accurate prediction of insertion probabilities improves detection of cancer driver genes from transposon mutagenesis screens

Keyphrases

• Prediction Accuracy 100%
• Cancer Detection 100%
• Mutagenesis Screen 100%
• Transposon mutagenesis 100%
• Cancer Driver Genes 100%
• Transposon System 100%
• Insertion Rate 100%
• Insertion Probability 100%
• Poisson Regression 66%
• Common Insertion Sites 66%
• Performance Improvement 33%
• Transcriptional Activity 33%
• Genomic Regions 33%
• Chromatin Accessibility 33%
• Oncogenesis 33%
• State-of-the-art Techniques 33%
• Freely Available 33%
• Rate-based 33%
• Transposon Insertion 33%
• Cancer Genes 33%
• Transposon 33%
• Sequence Context 33%
• Sample Information 33%
• In Vivo Assay 33%
• Transposon Screen 33%
• Intersample 33%
• Activity Setting 33%

Biochemistry, Genetics and Molecular Biology

• Transposable Element 100%
• Transposon Mutagenesis 100%
• Oncogene 16%
• Carcinogenesis 16%
• Genomics 16%