Tissue inhibitor of metalloproteinases-1-induced scattered liver metastasis is mediated by hypoxia-inducible factor-1 α

Keyphrases

• Tissue Inhibitor of metalloproteinase-1 (TIMP-1) 100%
• Liver Metastasis 100%
• Hypoxia-inducible factor-1α (HIF-1α) 100%
• Hepatocyte Growth Factor 50%
• Metastasis 33%
• Growth Factor Signaling 25%
• Invasiveness 16%
• Phosphorylation 16%
• Tumor Cells 16%
• Knockdown 16%
• Protease Web 16%
• Tissue Homeostasis 16%
• Cell-derived 8%
• Effector Molecules 8%
• Tumor Progression 8%
• Recombinant 8%
• Protease 8%
• Protease Inhibitors 8%
• Stress Conditions 8%
• Overexpressing 8%
• Microenvironment 8%
• Lymphoma Cells 8%
• Stress-related 8%
• T-cell Lymphoma 8%
• Lack of Oxygen 8%
• Host Level 8%
• Growth Factor Pathway 8%
• HIF-1 Signaling Pathway 8%
• Hepatocyte Growth Factor Receptor 8%
• In Vivo Exposure 8%
• Target Organ 8%

Pharmacology, Toxicology and Pharmaceutical Science

• Tissue Inhibitor of Metalloproteinase 1 100%
• Hypoxia Inducible Factor 1 100%
• Liver Metastasis 100%
• Hypoxia Inducible Factor 100%
• Scatter Factor 60%
• Proteinase 30%
• Neoplasm 20%
• Tissue Inhibitor of Metalloproteinase 10%
• Tumor Growth 10%
• Proteinase Inhibitor 10%
• T Cell Lymphoma 10%
• Scatter Factor Receptor 10%

Biochemistry, Genetics and Molecular Biology

• Hypoxia Inducible Factor 1 100%
• Metalloprotease Inhibitor 100%
• Hypoxia-Inducible Factors 90%
• Hepatocyte Growth Factor 63%
• Protease 27%
• Homeostasis 18%
• Protease Inhibitor 9%
• Mediator 9%
• Upregulation 9%
• Target Organ 9%
• Tumor Progression 9%
• Growth Factor Receptor 9%