The influence of different metal-chelate conjugates of pentixafor on the CXCR4 affinity

Keyphrases

• 125I 16%
• 68Ga-pentixafor 50%
• C-X-C Chemokine Receptor Type 4 (CXCR4) 100%
• Chelates 16%
• Chelator 50%
• Competitive Binding Assay 16%
• CXCR4 Receptor 33%
• Cyclic Pentapeptide 33%
• Diagnostic Targets 16%
• Endoradiotherapy 16%
• Epithelial Cancer 16%
• Epithelial-mesenchymal 16%
• FC131 16%
• Hematopoietic Cancer 16%
• IC50 16%
• In Vivo Properties 16%
• Jurkat T Cells 16%
• Leukemia Cells 16%
• Linker 16%
• Metal Chelates 100%
• Metalates 16%
• Overexpression 16%
• Pentapeptide 50%
• Pentixafor 100%
• Preclinical Evaluation 16%
• Radioligand 16%
• Radiometals 16%
• Radiopharmaceuticals 16%
• Receptor Affinity 50%
• Solid-phase Peptide Synthesis 33%
• Solution-phase Peptide Synthesis 16%
• Structural Modification 16%
• T-cell Leukemia 16%
• Therapeutic Target 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Arginine 20%
• Chelate 20%
• Chelating Agent 60%
• Chemokine Receptor 20%
• Chemokine Receptor CXCR4 40%
• Gallium 68 60%
• IC50 20%
• Iodine-125 20%
• Metal Chelate 100%
• Pentapeptide 100%
• Radioligand 20%
• Receptor 40%
• T Cell Leukemia 20%
• Tetraxetan 40%

Chemistry

• Arginine 20%
• chelate 100%
• Chelating Agent 60%
• Chemokine 20%
• DOTA 40%
• IC50 20%
• Pentapeptide 100%
• Peptide Synthesis 40%
• Radioligand 20%
• Radiopharmaceutical 20%