The immune network in pancreatic cancer development and progression

S. M. Wörmann; K. N. Diakopoulos; M. Lesina; H. Algül

doi:10.1038/onc.2013.257

The immune network in pancreatic cancer development and progression

S. M. Wörmann, K. N. Diakopoulos, M. Lesina, H. Algül

Technische Universität München

Publikation: Beitrag in Fachzeitschrift › Übersichtsartikel › Begutachtung

161 Zitate (Scopus)

Abstract

The presence of stromal desmoplasia is a hallmark of spontaneous pancreatic ductal adenocarcinoma, forming a unique microenvironment that comprises many cell types. Only recently, the immune system has entered the pathophysiology of pancreatic ductal adenocarcinoma development. Tumor cells in the pancreas seem to dysbalance the immune system, thus facilitating spontaneous cancer development. This review will try to assemble all relevant data to demonstrate the implications of the immune network on spontaneous cancer development..

Originalsprache	Englisch
Seiten (von - bis)	2956-2967
Seitenumfang	12
Fachzeitschrift	Oncogene
Jahrgang	33
Ausgabenummer	23
DOIs	https://doi.org/10.1038/onc.2013.257
Publikationsstatus	Veröffentlicht - 5 Juni 2014
Extern publiziert	Ja

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KW - immune cells

KW - immune system

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The immune network in pancreatic cancer development and progression

Abstract

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