@article{8d56190035964b918bd49ac0d4a57418,
title = "The glucocorticoid receptor recruits the COMPASS complex to regulate inflammatory transcription at macrophage enhancers",
abstract = "Glucocorticoids such as dexamethasone are widely used immunomodulators. Combining proteomics, ChIP-seq, RNA-seq, and genetic loss-of-function studies in murine macrophages, Greulich et al. show that recruitment of the SETD1A/COMPASS complex to cis-regulatory elements by the glucocorticoid receptor mediates some of their anti-inflammatory actions.",
keywords = "COMPASS complex, H3K4 methylation, SETD1A, dexamethasone, enhancers, genomics, glucocorticoid receptor, inflammation, macrophages, transcription",
author = "Franziska Greulich and Michael Wierer and Aikaterini Mechtidou and Omar Gonzalez-Garcia and Uhlenhaut, {N. Henriette}",
note = "Publisher Copyright: {\textcopyright} 2021 The Authors",
year = "2021",
month = feb,
day = "9",
doi = "10.1016/j.celrep.2021.108742",
language = "English",
volume = "34",
journal = "Cell Reports",
issn = "2211-1247",
publisher = "Cell Press",
number = "6",
}