The Antibody Light-Chain Linker Regulates Domain Orientation and Amyloidogenicity

Keyphrases

• Linker 100%
• Domain Orientation 100%
• Light Chain 100%
• Amyloidogenicity 100%
• Antibody Light Chain 100%
• Variable Domains 42%
• Relative Orientation 28%
• Fibril Formation 28%
• Two-component Domains 28%
• Immunoglobulin 14%
• Structural Integrity 14%
• Proteolysis 14%
• Biotechnology 14%
• Residual Dipolar Couplings 14%
• Antigen Binding 14%
• Organ Failure 14%
• Light Chain Amyloidosis 14%
• Amyloidosis 14%
• Protein Amyloids 14%
• Extended Linker 14%
• Flexible Conformation 14%
• Light Property 14%
• Chain Domain 14%

Immunology and Microbiology

• Light Chain 100%
• Immunology 100%
• Fibril 30%
• Binding Antibody 10%
• Residual Dipolar Coupling 10%
• Protein Degradation 10%
• Amino Terminal Sequence 10%
• Conformation 10%
• Amyloidosis 10%

Biochemistry, Genetics and Molecular Biology

• Light Chain 100%
• Protein Catabolism 10%
• Immunoglobulin 10%
• N-Terminus 10%
• Conformation 10%
• Antigen Binding 10%
• Amyloidosis 10%
• Residual Dipolar Coupling 10%
• Amyloid Protein 10%
• Chlordiazepoxide 10%