Targeted magnetic liposomes loaded with doxorubicin

Pallab Pradhan, Rinti Banerjee, Dhirendra Bahadur, Christian Koch, Olga Mykhaylyk, Christian Plank

Publikation: Beitrag in Buch/Bericht/KonferenzbandKapitelBegutachtung

9 Zitate (Scopus)

Abstract

Targeted delivery systems for anticancer drugs are urgently needed to achieve maximum therapeutic efficacy by site-specific accumulation and thereby minimizing adverse effects resulting from systemic distribution of many potent anticancer drugs. We have prepared folate receptor-targeted magnetic liposomes loaded with doxorubicin, which are designed for tumor targeting through a combination of magnetic and biological targeting. Furthermore, these liposomes are designed for hyperthermia-induced drug release to be mediated by an alternating magnetic field and to be traceable by magnetic resonance imaging (MRI). Here, detailed preparation and relevant characterization techniques of targeted magnetic liposomes encapsulating doxorubicin are described.

OriginalspracheEnglisch
TitelMethods in Molecular Biology
Herausgeber (Verlag)Humana Press Inc.
Seiten257-272
Seitenumfang16
DOIs
PublikationsstatusVeröffentlicht - 2017

Publikationsreihe

NameMethods in Molecular Biology
Band1522
ISSN (Print)1064-3745

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