Systemically administered neuregulin-1β1 rescues nigral dopaminergic neurons via the ErbB4 receptor tyrosine kinase in MPTP mouse models of Parkinson's disease

Keyphrases

• Mouse Model 100%
• Receptor Tyrosine Kinase 100%
• Parkinson's Disease Model 100%
• Neuregulin-1 (NRG1) 100%
• 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 100%
• Nigral Dopaminergic Neuron 100%
• ErbB4 Receptor 100%
• 1-methyl-4-phenylpyridinium 20%
• ErbB4 20%
• Striatum 10%
• Substantia Nigra 10%
• Parkinson's Disease 10%
• Parkinson Patients 10%
• Knock-in Mouse Model 10%
• Dopaminergic Neurons 10%
• Intoxication 10%
• Insults 10%
• Blood-brain Barrier 10%
• Neuroprotective Properties 10%
• Wild Mice 10%
• Extracellular Domain 10%
• Differentiation Factors 10%
• Toxic Metabolites 10%
• Nerve Growth Factor 10%
• Dopamine Transporter 10%
• 6-hydroxydopamine (6-OHDA) 10%
• Intracellular Uptake 10%
• Saline Control 10%
• Midbrain Dopaminergic Neurons 10%
• Dopamine Level 10%
• Subchronic 10%
• Dopaminergic Fiber 10%
• Nerve Differentiation 10%
• Nigrostriatal Damage 10%
• Disease-related 10%

Neuroscience

• Parkinson's Disease 100%
• Dopaminergic Neuron 100%
• Receptor Tyrosine Kinase 100%
• Neu Differentiation Factor 100%
• Tetrahydropyridine 100%
• Epidermal Growth Factor Receptor 4 100%
• MPP+ 20%
• Dopaminergic 10%
• Striatum 10%
• Substantia nigra 10%
• Midbrain 10%
• Neuroprotective Agent 10%
• Oxidopamine 10%
• Treatment of Parkinson's Disease 10%
• Dopamine Transporter 10%
• Blood Brain Barrier 10%
• Nerve Growth 10%
• Nigrostriatal Pathway 10%
• Toxic Injury 10%