Regulation of Na+/Ca2+ exchange current in the normal and failing heart

Michael Reppel, Bernd K. Fleischmann, Hannes Reuter, Frank Pillekamp, Heribert Schunkert, Jürgen Hescheler

Publikation: Beitrag in Buch/Bericht/KonferenzbandKonferenzbeitragBegutachtung

12 Zitate (Scopus)

Abstract

Cardiac NCX is modulated by diverse regulatory elements. Although there is consensus about the regulatory function of Na+ and Ca2+ and other elements, for example, ATP, there is still a controversial debate about the functional role of cyclic nucleotides and protein kinases. Future studies should focus on that topic since disturbances of cAMP/cGMP concentration and kinase activity may lead to severe functional disorders in the diseased heart. S100A1 is presumably a novel regulator of NCX.

OriginalspracheEnglisch
TitelSodium-Calcium Exchange and the Plasma Membrane Ca2+ATPase in Ce;; Funcyion
UntertitelFifth International Conference
Herausgeber (Verlag)Blackwell Publishing Inc.
Seiten361-372
Seitenumfang12
ISBN (Print)1573316490, 9781573316491
DOIs
PublikationsstatusVeröffentlicht - März 2007
Extern publiziertJa

Publikationsreihe

NameAnnals of the New York Academy of Sciences
Band1099
ISSN (Print)0077-8923
ISSN (elektronisch)1749-6632

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