Quantitative phase-contrast X-ray micro CT for visualization of mouse lymph nodes

Mirko Riedel, Jörg U. Hammel, Julian Moosmann, Felix Beckmann, Florian Schwarzenberg, Paul Schuetz, Stephan Henne, Clemens Wülfing, Madleen Busse, Julia Herzen

Publikation: Beitrag in Buch/Bericht/KonferenzbandKonferenzbeitragBegutachtung

1 Zitat (Scopus)

Abstract

Previously, we designed a new quantitative phase-contrast setup for the microtomography experiments at the hereon beamlines P05 and P07 at PETRA III, DESY. This setup is based on Talbot array illuminators (TAI) as high visibility wavefront markers and can reach a spatial resolution level comparable to propagation-based imaging. In this work, we focus on the progress of bringing this setup into user operation. We collaborated with INI-Research to investigate the vascular system of mouse lymph nodes, exploiting the spatial resolution capabilities and using the quantitative aspect of the data to compare different sample preparation methods. We could successfully visualize and trace the blood supply of the lymph nodes, even with fine capillaries, showing the stability and performance of the setup in user application.

OriginalspracheEnglisch
TitelDevelopments in X-Ray Tomography XIV
Redakteure/-innenBert Muller, Ge Wang
Herausgeber (Verlag)SPIE
ISBN (elektronisch)9781510654686
DOIs
PublikationsstatusVeröffentlicht - 2022
VeranstaltungDevelopments in X-Ray Tomography XIV 2022 - San Diego, USA/Vereinigte Staaten
Dauer: 22 Aug. 202224 Aug. 2022

Publikationsreihe

NameProceedings of SPIE - The International Society for Optical Engineering
Band12242
ISSN (Print)0277-786X
ISSN (elektronisch)1996-756X

Konferenz

KonferenzDevelopments in X-Ray Tomography XIV 2022
Land/GebietUSA/Vereinigte Staaten
OrtSan Diego
Zeitraum22/08/2224/08/22

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