Protein Adsorption and Adhesion of blood platelets on silicone rubber under static and dynamic flow conditions

Cécile Boudot, Stefanie Recht, Markus Eblenkamp, Miriam Haerst, Erich Wintermantel

Publikation: Beitrag in Buch/Bericht/KonferenzbandKonferenzbeitragBegutachtung

1 Zitat (Scopus)

Abstract

Understanding the spontaneous protein adsorption on biomaterial surfaces is a key element to evaluate their thrombogenicity and especially their propensity to trigger the adhesion of blood platelets (thrombocytes). In this work, the adhesion of two proteins (bovine fibrinogen and bovine serum albumin) on silicone rubber and the thrombocyte adhesion on different preadsorbed protein layers has been investigated under static and dynamic flow conditions. It has been shown that proteins do not adhere equally to silicone rubber and that both the composition of protein layer and the flow conditions influence the thrombocyte adhesion.

OriginalspracheEnglisch
Titel6th European Conference of the International Federation for Medical and Biological Engineering - MBEC 2014
Redakteure/-innenIgor Lackovic, Darko Vasic
Herausgeber (Verlag)Springer Verlag
Seiten541-544
Seitenumfang4
ISBN (elektronisch)9783319111278
DOIs
PublikationsstatusVeröffentlicht - 2015
Veranstaltung6th European Conference of the International Federation for Medical and Biological Engineering, MBEC 2014 - Dubrovnik, Kroatien
Dauer: 7 Sept. 201411 Sept. 2014

Publikationsreihe

NameIFMBE Proceedings
Band45
ISSN (Print)1680-0737

Konferenz

Konferenz6th European Conference of the International Federation for Medical and Biological Engineering, MBEC 2014
Land/GebietKroatien
OrtDubrovnik
Zeitraum7/09/1411/09/14

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