TY - CHAP
T1 - Principles
AU - Filser, Johannes G.
AU - Buters, Jeroen T.M.
AU - Schwarz, Leslie
AU - Watkins, John B.
AU - Stanley, Lesley
AU - Schlossmann, Jens
AU - Hofmann, Franz
AU - Feron, Victor J.
AU - Jonker, Diana
AU - Efferth, Thomas
AU - Kaina, Bernd
AU - Spielmann, Horst
AU - Calow, Peter
AU - Forbes, Valery E.
PY - 2008/2/8
Y1 - 2008/2/8
N2 - The object of toxicokinetics is the investigation of absorption, distribution, and elimination of toxicants and their toxicologically relevant metabolites as functions of dose and time.
AB - The object of toxicokinetics is the investigation of absorption, distribution, and elimination of toxicants and their toxicologically relevant metabolites as functions of dose and time.
KW - Anion-transport systems
KW - Cancer-linked disease
KW - Enzyme-mediated substance conversion
KW - Intravascular thrombus formation
KW - Isoenzymes exhibiting different substrate specificities
KW - Messenger ribonucleic acid (mRNA)
KW - Morphologically and functionally differing entities
KW - One-compartment model saturation kinetics
KW - Richly perfused organs
KW - Toxic potential and (estimated) exposure
UR - http://www.scopus.com/inward/record.url?scp=84889492924&partnerID=8YFLogxK
U2 - 10.1002/9780470868959.ch2
DO - 10.1002/9780470868959.ch2
M3 - Chapter
AN - SCOPUS:84889492924
SN - 9780470868935
SP - 19
EP - 203
BT - Toxicology and Risk Assessment
PB - John Wiley & Sons, Ltd
ER -