Preoperative angiographic considerations and neurological outcome after surgical treatment of intradural spinal hemangioblastoma: a multicenter retrospective case series

Vicki M. Butenschoen, Maximilian Schwendner, Vanessa Hubertus, Julia Onken, Nikolaus Koegl, Theresa Mohme, Stefanie Maurer, Tobias Boeckh-Behrens, Sven O. Eicker, Claudius Thomé, Peter Vajkoczy, Marcus Czabanka, Bernhard Meyer, Maria Wostrack

Publikation: Beitrag in FachzeitschriftArtikelBegutachtung

2 Zitate (Scopus)

Abstract

Purpose: Intradural spinal hemangioblastomas are rare highly hypervascularized benign neoplasms. Surgical resection remains the treatment of choice, with a significant risk of postoperative neurological deterioration. Due to the tumor infrequency, scientific evidence is scarce and limited to case reports and small case series. Methods: We performed a retrospective multicenter study including five high-volume neurosurgical centers analyzing patients surgically treated for spinal hemangioblastomas between 2006 and 2021. We assessed clinical status, surgical data, preoperative angiograms, and embolization when available. Follow-up records were analyzed, and logistic regression performed to assess possible risk factors for neurological deterioration. Results: We included 60 patients in Germany and Austria. Preoperative angiography was performed in 30% of the cases; 10% of the patients underwent preoperative embolization. Posterior tumor location and presence of a syrinx favored gross total tumor resection (93.8% vs. 83.3% and 97.1% vs. 84%). Preoperative embolization was not associated with postoperative worsening. The clinical outcome revealed a transient postoperative neurological deterioration in 38.3%, depending on symptom duration and preoperative modified McCormick grading, but patients recovered in most cases until follow-up. Conclusion: Spinal hemangioblastoma patients significantly benefit from early surgical treatment with only transient postoperative deterioration and complete recovery until follow-up. The performance of preoperative angiograms remains subject to center disparities.

OriginalspracheEnglisch
Seiten (von - bis)107-115
Seitenumfang9
FachzeitschriftJournal of Neuro-Oncology
Jahrgang161
Ausgabenummer1
DOIs
PublikationsstatusVeröffentlicht - Jan. 2023
Extern publiziertJa

Fingerprint

Untersuchen Sie die Forschungsthemen von „Preoperative angiographic considerations and neurological outcome after surgical treatment of intradural spinal hemangioblastoma: a multicenter retrospective case series“. Zusammen bilden sie einen einzigartigen Fingerprint.

Dieses zitieren