Precancerous lesions of the biliary tree

Günter Klöppel, Volkan Adsay, Björn Konukiewitz, Jörg Kleeff, Anna Melissa Schlitter, Irene Esposito

Publikation: Beitrag in FachzeitschriftÜbersichtsartikelBegutachtung

66 Zitate (Scopus)

Abstract

The neoplasms of the biliary tree include the carcinomas of the intra- and extrahepatic bile ducts, the gallbladder and the ampulla. Two types of precancerous lesions precede these adenocarcinomas: the flat and non-tumour forming type that is called biliary intraepithelial neoplasia, and the papillary and tumour-forming type that has been named intraductal papillary neoplasm of the bile duct. Rarely also biliary mucinous cystic neoplasm can give rise to invasive biliary adenocarcinomas. This review discusses the pathological, molecular, epidemiological, clinical and prognostic features of the precancerous biliary lesions, separated according to their origin in the bile ducts, the ampulla and the gall bladder.

OriginalspracheEnglisch
Seiten (von - bis)285-297
Seitenumfang13
FachzeitschriftBailliere's Best Practice and Research in Clinical Gastroenterology
Jahrgang27
Ausgabenummer2
DOIs
PublikationsstatusVeröffentlicht - Apr. 2013

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