Phosphorylation activates the yeast small heat shock protein Hsp26 by weakening domain contacts in the oligomer ensemble

Keyphrases

• Phosphorylation 100%
• Small Heat Shock Protein (sHSP) 100%
• Hsp26 100%
• Chaperone Activity 50%
• Phosphorylation Sites 33%
• Negative Charge 16%
• Dissociation 16%
• Protein Binding 16%
• Thermal Sensor 16%
• Heat Stress 16%
• Saccharomyces Cerevisiae 16%
• Heat Shock 16%
• N-terminal Domain 16%
• Substrate Proteins 16%
• Shock Temperature 16%
• Phosphomimetic mutation 16%
• Proteotoxic Stress 16%
• Domain-domain Interaction 16%
• Cryo-EM Structure 16%
• C-terminal Extension 16%

Biochemistry, Genetics and Molecular Biology

• N-Terminus 100%
• Heat Shock Protein 100%
• Binding Protein 50%
• C-Terminus 50%
• Heat Stress 50%
• Heat Shock 50%
• Saccharomyces cerevisiae 50%
• Cryoelectron Microscopy 50%