TY - CHAP
T1 - Online interactive microbial classification and geospatial distributional analysis using BioAtlas
AU - Lund, Jesper
AU - Tan, Qihua
AU - Baumbach, Jan
N1 - Publisher Copyright:
© Springer Science+Business Media, LLC, part of Springer Nature 2018.
PY - 2018
Y1 - 2018
N2 - In recent decades, the accumulation of data on 16s ribosomal RNA genes has yielded free and public databases such as SILVA, GreenGenes, The Ribosomal Database Project, and IMG, handling massive amounts of raw data and meta information. 16s rRNA gene contains hypervariable regions with great classification power. As a result, numerous classification tools have emerged including state-of-the-art tools such as Mothur, Qiime, and the 16s classifier. However, there is a gap between the sequence databases, the taxonomy profiling tools and available meta information such as geo/body-location information. Here, we present BioAtlas, and interactive web tool for searching, exploring, and analyzing prokaryotic distributions by integration of various resources of metagenomics databases. In the following section we show how to use BioAtlas to (1) search and explore prokaryote occurrences across the geospatial map of the world, (2) investigate and hunt for occurrences across generic user-generated surface-specific maps, with an example map of a human female, with data from Bouslimani et al., and (3) classify a user-given sequences dataset through our online platform for visual exploration of the spatial abundances of the identified microbes.
AB - In recent decades, the accumulation of data on 16s ribosomal RNA genes has yielded free and public databases such as SILVA, GreenGenes, The Ribosomal Database Project, and IMG, handling massive amounts of raw data and meta information. 16s rRNA gene contains hypervariable regions with great classification power. As a result, numerous classification tools have emerged including state-of-the-art tools such as Mothur, Qiime, and the 16s classifier. However, there is a gap between the sequence databases, the taxonomy profiling tools and available meta information such as geo/body-location information. Here, we present BioAtlas, and interactive web tool for searching, exploring, and analyzing prokaryotic distributions by integration of various resources of metagenomics databases. In the following section we show how to use BioAtlas to (1) search and explore prokaryote occurrences across the geospatial map of the world, (2) investigate and hunt for occurrences across generic user-generated surface-specific maps, with an example map of a human female, with data from Bouslimani et al., and (3) classify a user-given sequences dataset through our online platform for visual exploration of the spatial abundances of the identified microbes.
KW - 16s gene
KW - Data mining
KW - Distributional analysis
KW - Integration
KW - Maps
KW - Metadata
KW - Microbiology
KW - Online tool
KW - Ribosomal RNA
KW - Taxonomic classification
UR - http://www.scopus.com/inward/record.url?scp=85051193041&partnerID=8YFLogxK
U2 - 10.1007/978-1-4939-8561-6_3
DO - 10.1007/978-1-4939-8561-6_3
M3 - Chapter
C2 - 30030801
AN - SCOPUS:85051193041
T3 - Methods in Molecular Biology
SP - 21
EP - 35
BT - Methods in Molecular Biology
PB - Humana Press Inc.
ER -