Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): A genetic association study in UK Biobank

Keyphrases

• UK Biobank 100%
• Genetic Association Studies 100%
• Forced Expiratory Volume in 1 Second (FEV1) 100%
• Lung Function 100%
• Chronic Obstructive Pulmonary Disease 100%
• Smoking Behavior 100%
• Genetic Causes 44%
• Airway Obstruction 33%
• Lung Health 33%
• Heavy Smokers 33%
• Never-smokers 33%
• Lung Disease 22%
• KANSL1 22%
• NCAM1 22%
• Between-person 11%
• Pathophysiology 11%
• Genetic Basis 11%
• European Ancestry 11%
• Genome-wide Significance 11%
• Genomic Regions 11%
• Shared Genetics 11%
• Custom Array 11%
• HLA-DQB1 11%
• Rare Coding Variants 11%
• Novel Variants 11%
• Novel Locus 11%
• Medical Research Council 11%
• Low-frequency Variants 11%
• Sample Selection 11%
• Brain Tissue 11%
• Specific Mechanisms 11%
• Asthma 11%
• Behavior Health 11%
• Tet Methylcytosine Dioxygenase 2 11%
• Chromosome 11 11%
• Trans Effect 11%
• Tobacco Addiction 11%
• Copy number 11%
• Chromosome 2 11%
• Smoking History 11%
• TBX5 11%
• UK Population 11%
• Airway Disease 11%
• Epigenetic Gene Regulation 11%
• Biobank Participants 11%
• Shared Genetic Architecture 11%
• Function Distribution 11%
• UK Biobank Data 11%
• Pack-years 11%
• TSEN54 11%
• DQA2 11%
• 5′-end 11%
• Wide Coverage 11%

Biochemistry, Genetics and Molecular Biology

• Genetics 100%
• Genetic Association Study 100%
• Forced Expiratory Volume 100%
• Airflow 33%
• Epigenetics 11%
• Genetic Architecture 11%
• Gene Control 11%
• Chromosome 11 11%
• Chromosome 2 11%
• HLA-DQB1 11%
• Genomics 11%

Immunology and Microbiology

• Forced Expiratory Volume 100%
• Genetic Association Study 100%
• Airflow 33%
• HLA DQB1 Antigen 11%
• Asthma 11%
• Brain Tissue 11%
• Gene Control 11%
• Chromosome 11 11%
• Chromosome 2 11%
• Airway 11%