New variant of the human metapneumovirus (HMPV) associated with an acute and severe exacerbation of asthma bronchiale

Oliver Schildgen; Tilman Geikowski; Thomas Glatzel; Arne Simon; Anja Wilkesmann; Michael Roggendorf; Sergei Viazov; Bertfried Matz

doi:10.1016/j.jcv.2004.06.007

New variant of the human metapneumovirus (HMPV) associated with an acute and severe exacerbation of asthma bronchiale

Oliver Schildgen, Tilman Geikowski, Thomas Glatzel, Arne Simon, Anja Wilkesmann, Michael Roggendorf, Sergei Viazov, Bertfried Matz

Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

35 Zitate (Scopus)

Abstract

Recently, an increasing number of studies demonstrated that the human metapneumovirus (HMPV) causes mild to severe respiratory infections in children and immunosuppressed adults, and may be a frequent but somewhat undervalued pathogen. Here, we report the detection of a new variant of HMPV that is not closely related to the HMPV strains described until now. The strain was detected in a 6.5-year-old girl with an acute and severe exacerbation of asthma bronchiale triggered by an infection with a newly detected HMPV variant. The presented data provide new information on genetic heterogeneity of HMPV and necessitate an optimization of diagnostic procedures for the detection of HMPV infection.

Originalsprache	Englisch
Seiten (von - bis)	283-288
Seitenumfang	6
Fachzeitschrift	Journal of Clinical Virology
Jahrgang	31
Ausgabenummer	4
DOIs	https://doi.org/10.1016/j.jcv.2004.06.007
Publikationsstatus	Veröffentlicht - Dez. 2004
Extern publiziert	Ja

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abstract = "Recently, an increasing number of studies demonstrated that the human metapneumovirus (HMPV) causes mild to severe respiratory infections in children and immunosuppressed adults, and may be a frequent but somewhat undervalued pathogen. Here, we report the detection of a new variant of HMPV that is not closely related to the HMPV strains described until now. The strain was detected in a 6.5-year-old girl with an acute and severe exacerbation of asthma bronchiale triggered by an infection with a newly detected HMPV variant. The presented data provide new information on genetic heterogeneity of HMPV and necessitate an optimization of diagnostic procedures for the detection of HMPV infection.",

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author = "Oliver Schildgen and Tilman Geikowski and Thomas Glatzel and Arne Simon and Anja Wilkesmann and Michael Roggendorf and Sergei Viazov and Bertfried Matz",

note = "Funding Information: Sergei Viazov was supported by a Grant from the IFORES program of the Medical Faculty of the University of Essen.",

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doi = "10.1016/j.jcv.2004.06.007",

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AU - Schildgen, Oliver

AU - Geikowski, Tilman

AU - Glatzel, Thomas

AU - Simon, Arne

AU - Wilkesmann, Anja

AU - Roggendorf, Michael

AU - Viazov, Sergei

AU - Matz, Bertfried

N1 - Funding Information: Sergei Viazov was supported by a Grant from the IFORES program of the Medical Faculty of the University of Essen.

PY - 2004/12

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AB - Recently, an increasing number of studies demonstrated that the human metapneumovirus (HMPV) causes mild to severe respiratory infections in children and immunosuppressed adults, and may be a frequent but somewhat undervalued pathogen. Here, we report the detection of a new variant of HMPV that is not closely related to the HMPV strains described until now. The strain was detected in a 6.5-year-old girl with an acute and severe exacerbation of asthma bronchiale triggered by an infection with a newly detected HMPV variant. The presented data provide new information on genetic heterogeneity of HMPV and necessitate an optimization of diagnostic procedures for the detection of HMPV infection.

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New variant of the human metapneumovirus (HMPV) associated with an acute and severe exacerbation of asthma bronchiale

Abstract

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