Neurologische komplikationen der HIV-infektion in der HAART-ära

Despite the undisputable therapeutic success of highly active antiretroviral therapy (HAART), neurological complications of HIV-infection are still an unresolved problem. Most important are the directly HIV-associated complications, which comprise HIV-associated encephalopathy, myelopathy as well as peripheral neuropathies and muscle diseases. Among the nowadays relevant opportunistic infections are toxoplasma encephalitis and JC-virus related progressive multifocal leukencephalopathy; finally neurological complications are provoked by so called immune reconstitution phenomena. This reviews' aim is to provide a diagnostic manual leading to appropriate therapy by effective diagnostic procedures.