Multi-scale systems genomics analysis predicts pathways, cell types, and drug targets involved in normative variation in peri-adolescent human cognition

Keyphrases

• Human Cognition 100%
• System Level 100%
• Multiscale Systems 100%
• Drug Target 100%
• Genomic Analysis 100%
• Systems Genomics 100%
• Preadolescence 100%
• FBLN1 100%
• Working Memory 50%
• Cognitive Task 50%
• Human Brain 50%
• Schizophrenia 50%
• Binarization 50%
• System Analysis 50%
• Parkinson's Disease 50%
• Genotype 50%
• Genome-wide Significance 50%
• Genetic Loci 50%
• Adult Brain 50%
• Brain Development 50%
• Path Analysis 50%
• Human Genetics 50%
• Gene Locus 50%
• Neurodevelopment 50%
• Diffusion Tensor Imaging 50%
• Fractional Anisotropy 50%
• Imaging Data 50%
• Fetal Brain 50%
• Reasoning Ability 50%
• Biomedical Domain 50%
• Single-cell Transcriptomics 50%
• Omics 50%
• Genotype P 50%
• Autonomic Dysfunction 50%
• Pathway Genes 50%
• Genotype-phenotype Analysis 50%
• Working Memory Deficits 50%
• Schizophrenia Symptoms 50%
• Poor Performers 50%
• Intermediate Progenitor Cell 50%
• Genotype Variation 50%
• Memory Accuracy 50%
• Complex Reasoning 50%
• Philadelphia Neurodevelopmental Cohort 50%
• Verbal Reasoning 50%
• Adolescent Cognition 50%
• Continental Ancestry 50%
• Fibulin-1 50%
• 3' End 50%
• White Matter Fractional Anisotropy 50%
• Developmental Cognition 50%

Biochemistry, Genetics and Molecular Biology

• Genotyping 100%
• Gene Locus 100%
• Working Memory 100%
• Fractional Anisotropy 100%
• Genomics 100%
• Genetics 50%
• Genetic Divergence 50%
• Facilitated Diffusion 50%
• Human Genetics 50%
• Allele 50%
• Nerve Cell Differentiation 50%
• System Analysis 50%
• Fibulin 50%
• Progenitor Cell 50%
• Tamsulosin 50%
• Transcriptome 50%

Neuroscience

• Human Cognition 100%
• Fractional Anisotropy 100%
• Gene Locus 100%
• Working Memory 100%
• Behavior (Neuroscience) 50%
• Systems Analysis 50%
• Parkinson's Disease 50%
• Transcriptome 50%
• Diffusion Tensor Imaging 50%
• Autonomic Nervous System 50%
• Nervous System Dysfunction 50%
• Nerve Cell Differentiation 50%
• Fibulin 50%
• Progenitor Cell 50%
• Tamsulosin 50%