Morphologische Kriterien in der hochauflösenden optischen Kohärenztomografie (SD-OCT) als prognostischer Faktor der Behandlung des Makulaödems bei retinalen venösen Verschlüssen

T. Groneberg, J. S. Trattnig, N. Feucht, C. P. Lohmann, M. Maier

Publikation: Beitrag in FachzeitschriftArtikelBegutachtung

11 Zitate (Scopus)

Abstract

Background: SD-OCT is an important tool in the diagnosis of macular oedema (ME) due to retinal vein occlusion (RVO). Its high resolution makes it possible to distinguish various morphological characteristics and differences. The aim of this study is to evaluate the correlation between morphological patterns and the development of visual acuity (VA) after intravitreal treatment of ME due to RVO. Methods: 81 patients on intravitreal treatment (dexamethasone: n = 53/ranibizumab: n = 28) due to ME associated with branch and central retinal vein occlusion (BRVO: n = 38/CRVO: n = 43) were retrospectively reviewed. Preoperative SD-OCT images were analysed by vitreous adhesion, epiretinal membranes, foveal contour, height of intraretinal cystoid spaces, inner and outer segment integrity and presence of subretinal fluid. The influence of these patterns on VA improvement was analysed. Results: In almost every morphological pattern, the data were highly variable. Therapy was effective, with a medium gain in VA of 9.51 letters ETDRS (dexamethasone: 9.62 letters/ranibizumab: 9.29 letters). The improvement in VA in patients with small intraretinal cystoid spaces (thickness ≤ 250 μm) was 19.44 letters ETDRS, compared to 7.23 letters ETDRS in patients with confluent cystoid spaces (p = 0.009). Patients with a convex fovea exhibited more pronounced reduction in central retinal thickness (CRT) (p = 0.004). Conclusion: Analysis of OCT has concentrated on demonstrating oedema and CRT. Our data indicate that detailed OCT morphology and the size of intraretinal cystoid spaces offer important information about VA prognosis after intravitreal therapy in ME due to RVO.

Titel in ÜbersetzungMorphologic Patterns on Spectral-Domain Optical Coherence Tomography (SD-OCT) as a Prognostic Indicator in Treatment of Macular Edema Due to Retinal Vein Occlusion
OriginalspracheDeutsch
Seiten (von - bis)1056-1062
Seitenumfang7
FachzeitschriftKlinische Monatsblatter fur Augenheilkunde
Jahrgang233
Ausgabenummer9
DOIs
PublikationsstatusVeröffentlicht - 1 Sept. 2016
Extern publiziertJa

Schlagwörter

  • macular edema
  • optical coherence tomography
  • retina
  • vein occlusion

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