Monozyten und Makrophagen im direkten Kontakt mit TiAl6V4-Implantaten Eine In-vitro-Zytokinexpressionsstudie

Sybille Warmuth; Michaela Kosmann; Joachim Aigner; Erich Wintermantel; Dieter Scharnweber; Hartmut Worch

doi:10.3139/120.100640

Monozyten und Makrophagen im direkten Kontakt mit TiAl6V4-Implantaten Eine In-vitro-Zytokinexpressionsstudie

Sybille Warmuth, Michaela Kosmann, Joachim Aigner, Erich Wintermantel, Dieter Scharnweber, Hartmut Worch

Lehrstuhl für Ergonomie

Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

2 Zitate (Scopus)

Abstract

Mono cytes/Macrophages play a crucial role regarding the tissue interaction of biomaterials by producing proinflammatory mediators. In the present study, we investigate the phagocytic inflammation of several surface precoated Ti6Al4V implants. The various surfaces trigger different cytokine expression by primary blood monocytes. The in vitro cell culture model mimics cell-biomaterials interactions and identifies materials with the highest inflammatory power. However the relevance of these results concerning the in vivo behaviour of implant surface needs further validation.

Titel in Übersetzung	Monocytes and makronhages in contact with various coated Ti6Al4V implants - In vitro expression of cytokines
Originalsprache	Deutsch
Seiten (von - bis)	107-111
Seitenumfang	5
Fachzeitschrift	Materialpruefung/Materials Testing
Jahrgang	47
Ausgabenummer	3
DOIs	https://doi.org/10.3139/120.100640
Publikationsstatus	Veröffentlicht - 2005

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title = "Monozyten und Makrophagen im direkten Kontakt mit TiAl6V4-Implantaten Eine In-vitro-Zytokinexpressionsstudie",

abstract = "Mono cytes/Macrophages play a crucial role regarding the tissue interaction of biomaterials by producing proinflammatory mediators. In the present study, we investigate the phagocytic inflammation of several surface precoated Ti6Al4V implants. The various surfaces trigger different cytokine expression by primary blood monocytes. The in vitro cell culture model mimics cell-biomaterials interactions and identifies materials with the highest inflammatory power. However the relevance of these results concerning the in vivo behaviour of implant surface needs further validation.",

author = "Sybille Warmuth and Michaela Kosmann and Joachim Aigner and Erich Wintermantel and Dieter Scharnweber and Hartmut Worch",

year = "2005",

doi = "10.3139/120.100640",

language = "Deutsch",

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T1 - Monozyten und Makrophagen im direkten Kontakt mit TiAl6V4-Implantaten Eine In-vitro-Zytokinexpressionsstudie

AU - Warmuth, Sybille

AU - Kosmann, Michaela

AU - Aigner, Joachim

AU - Wintermantel, Erich

AU - Scharnweber, Dieter

AU - Worch, Hartmut

PY - 2005

Y1 - 2005

N2 - Mono cytes/Macrophages play a crucial role regarding the tissue interaction of biomaterials by producing proinflammatory mediators. In the present study, we investigate the phagocytic inflammation of several surface precoated Ti6Al4V implants. The various surfaces trigger different cytokine expression by primary blood monocytes. The in vitro cell culture model mimics cell-biomaterials interactions and identifies materials with the highest inflammatory power. However the relevance of these results concerning the in vivo behaviour of implant surface needs further validation.

AB - Mono cytes/Macrophages play a crucial role regarding the tissue interaction of biomaterials by producing proinflammatory mediators. In the present study, we investigate the phagocytic inflammation of several surface precoated Ti6Al4V implants. The various surfaces trigger different cytokine expression by primary blood monocytes. The in vitro cell culture model mimics cell-biomaterials interactions and identifies materials with the highest inflammatory power. However the relevance of these results concerning the in vivo behaviour of implant surface needs further validation.

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DO - 10.3139/120.100640

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Monozyten und Makrophagen im direkten Kontakt mit TiAl6V4-Implantaten Eine In-vitro-Zytokinexpressionsstudie

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