TY - GEN
T1 - Medical-based Deep Curriculum Learning for Improved Fracture Classification
AU - Jiménez-Sánchez, Amelia
AU - Mateus, Diana
AU - Kirchhoff, Sonja
AU - Kirchhoff, Chlodwig
AU - Biberthaler, Peter
AU - Navab, Nassir
AU - González Ballester, Miguel A.
AU - Piella, Gemma
N1 - Publisher Copyright:
© 2019, Springer Nature Switzerland AG.
PY - 2019
Y1 - 2019
N2 - Current deep-learning based methods do not easily integrate to clinical protocols, neither take full advantage of medical knowledge. In this work, we propose and compare several strategies relying on curriculum learning, to support the classification of proximal femur fracture from X-ray images, a challenging problem as reflected by existing intra- and inter-expert disagreement. Our strategies are derived from knowledge such as medical decision trees and inconsistencies in the annotations of multiple experts, which allows us to assign a degree of difficulty to each training sample. We demonstrate that if we start learning “easy” examples and move towards “hard”, the model can reach a better performance, even with fewer data. The evaluation is performed on the classification of a clinical dataset of about 1000 X-ray images. Our results show that, compared to class-uniform and random strategies, the proposed medical knowledge-based curriculum, performs up to 15% better in terms of accuracy, achieving the performance of experienced trauma surgeons.
AB - Current deep-learning based methods do not easily integrate to clinical protocols, neither take full advantage of medical knowledge. In this work, we propose and compare several strategies relying on curriculum learning, to support the classification of proximal femur fracture from X-ray images, a challenging problem as reflected by existing intra- and inter-expert disagreement. Our strategies are derived from knowledge such as medical decision trees and inconsistencies in the annotations of multiple experts, which allows us to assign a degree of difficulty to each training sample. We demonstrate that if we start learning “easy” examples and move towards “hard”, the model can reach a better performance, even with fewer data. The evaluation is performed on the classification of a clinical dataset of about 1000 X-ray images. Our results show that, compared to class-uniform and random strategies, the proposed medical knowledge-based curriculum, performs up to 15% better in terms of accuracy, achieving the performance of experienced trauma surgeons.
KW - Bone fractures
KW - Computer-aided diagnosis
KW - Curriculum learning
KW - Medical decision trees
KW - Multi-label classification
UR - http://www.scopus.com/inward/record.url?scp=85075831434&partnerID=8YFLogxK
U2 - 10.1007/978-3-030-32226-7_77
DO - 10.1007/978-3-030-32226-7_77
M3 - Conference contribution
AN - SCOPUS:85075831434
SN - 9783030322250
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 694
EP - 702
BT - Medical Image Computing and Computer Assisted Intervention – MICCAI 2019 - 22nd International Conference, Proceedings
A2 - Shen, Dinggang
A2 - Yap, Pew-Thian
A2 - Liu, Tianming
A2 - Peters, Terry M.
A2 - Khan, Ali
A2 - Staib, Lawrence H.
A2 - Essert, Caroline
A2 - Zhou, Sean
PB - Springer Science and Business Media Deutschland GmbH
T2 - 22nd International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2019
Y2 - 13 October 2019 through 17 October 2019
ER -