It's a Free for All-Insulin-Positive Cells Join the Group of Potential Progenitors for Pancreatic Ductal Adenocarcinoma

John P. Morris IV; Matthias Hebrok

doi:10.1016/j.ccr.2009.10.006

It's a Free for All-Insulin-Positive Cells Join the Group of Potential Progenitors for Pancreatic Ductal Adenocarcinoma

John P. Morris IV, Matthias Hebrok

University of California San Francisco

Publikation: Beitrag in Fachzeitschrift › Kurzer Abriss › Begutachtung

4 Zitate (Scopus)

Abstract

Despite significant efforts, the cellular compartment that gives rise to pancreatic ductal adenocarcinoma (PDAC), one of the most lethal human cancers, remains obscure. In this issue of Cancer Cell, Gidekel Friedlander and colleagues demonstrate that under conditions of tissue damage, mutant Kras can drive previously unsuspected insulin-positive endocrine cells into PDA.

Originalsprache	Englisch
Seiten (von - bis)	359-361
Seitenumfang	3
Fachzeitschrift	Cancer Cell
Jahrgang	16
Ausgabenummer	5
DOIs	https://doi.org/10.1016/j.ccr.2009.10.006
Publikationsstatus	Veröffentlicht - 6 Nov. 2009
Extern publiziert	Ja

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10.1016/j.ccr.2009.10.006

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title = "It's a Free for All-Insulin-Positive Cells Join the Group of Potential Progenitors for Pancreatic Ductal Adenocarcinoma",

abstract = "Despite significant efforts, the cellular compartment that gives rise to pancreatic ductal adenocarcinoma (PDAC), one of the most lethal human cancers, remains obscure. In this issue of Cancer Cell, Gidekel Friedlander and colleagues demonstrate that under conditions of tissue damage, mutant Kras can drive previously unsuspected insulin-positive endocrine cells into PDA.",

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It's a Free for All-Insulin-Positive Cells Join the Group of Potential Progenitors for Pancreatic Ductal Adenocarcinoma

Abstract

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