TY - JOUR
T1 - Iron oxide nanoparticles with supramolecular ureidopyrimidinone coating
AU - Turrina, Chiara
AU - Dankers, Patricia Y.W.
AU - Berensmeier, Sonja
AU - Schwaminger, Sebastian
N1 - Publisher Copyright:
© 2022 The Author(s), published by De Gruyter.
PY - 2022/8/1
Y1 - 2022/8/1
N2 - Superparamagnetic iron oxide nanoparticles are a promising material in nanomedicine, especially for generating magnetically controlled drug delivery systems. We developed an innovative ureidopyrimidinone (UPy) coating based on supramolecular hydrogen bonding units. The synthesized nanoparticles possess a positively charged surface with a hydrodynamic diameter of 177 nm at pH 7 and magnetization of 31 emu g-1. The system has the potential to be modified by drugs or bioactive molecules altered with UPy units.
AB - Superparamagnetic iron oxide nanoparticles are a promising material in nanomedicine, especially for generating magnetically controlled drug delivery systems. We developed an innovative ureidopyrimidinone (UPy) coating based on supramolecular hydrogen bonding units. The synthesized nanoparticles possess a positively charged surface with a hydrodynamic diameter of 177 nm at pH 7 and magnetization of 31 emu g-1. The system has the potential to be modified by drugs or bioactive molecules altered with UPy units.
KW - Cationic coating
KW - Iron oxide nanoparticles
KW - Supramolecular system
KW - Ureidopyrimidinone
UR - http://www.scopus.com/inward/record.url?scp=85137713728&partnerID=8YFLogxK
U2 - 10.1515/cdbme-2022-1004
DO - 10.1515/cdbme-2022-1004
M3 - Article
AN - SCOPUS:85137713728
SN - 2364-5504
VL - 8
SP - 13
EP - 16
JO - Current Directions in Biomedical Engineering
JF - Current Directions in Biomedical Engineering
IS - 2
ER -