Inhalative Analgosedierung auf der Intensivstation: Gefahr einer malignen Hyperthermie

W. Klingler; E. Pfenninger

doi:10.1007/s00063-018-0453-7

Inhalative Analgosedierung auf der Intensivstation: Gefahr einer malignen Hyperthermie

W. Klingler
, E. Pfenninger

Kliniken Landkreis Sigmaringen GmbH
University Medical Center Ulm and Center of Excellence 'Metabolic Disorders'

Publikation: Beitrag in Fachzeitschrift › Artikel › Begutachtung

2 Zitate (Scopus)

Abstract

Background: According to the 2010 S3 Guidelines, analgosedation is an option for ventilated patients in intensive care units (ICU). Therefore, adverse effects of volatile anesthetics can occur in areas outside of surgical medical fields. Objective: The aim is to inform ICU physicians about the clinical and legal challenges of a life-threatening pharmacogenetic reaction to inhalational anesthetics, malignant hyperthermia (MH). Discussion: Consequences of an MH crisis for doctors, patients, and relatives regarding patient rights legislation, as well as insurance and employment issues with respect to the German Genetic Diagnostics Act are discussed.

Titel in Übersetzung	Inhalational analgosedation in the intensive care unit: Risk of malignant hyperthermia
Originalsprache	Deutsch
Seiten (von - bis)	101-106
Seitenumfang	6
Fachzeitschrift	Medizinische Klinik - Intensivmedizin und Notfallmedizin
Jahrgang	115
Ausgabenummer	2
DOIs	https://doi.org/10.1007/s00063-018-0453-7
Publikationsstatus	Veröffentlicht - 1 März 2020
Extern publiziert	Ja

Schlagwörter

Dantrolene
General anesthesia
German Genetic Diagnostics Act
Malignant hyperthermia
Pharmacogenetics

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10.1007/s00063-018-0453-7

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abstract = "Background: According to the 2010 S3 Guidelines, analgosedation is an option for ventilated patients in intensive care units (ICU). Therefore, adverse effects of volatile anesthetics can occur in areas outside of surgical medical fields. Objective: The aim is to inform ICU physicians about the clinical and legal challenges of a life-threatening pharmacogenetic reaction to inhalational anesthetics, malignant hyperthermia (MH). Discussion: Consequences of an MH crisis for doctors, patients, and relatives regarding patient rights legislation, as well as insurance and employment issues with respect to the German Genetic Diagnostics Act are discussed.",

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T2 - Gefahr einer malignen Hyperthermie

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AU - Pfenninger, E.

PY - 2020/3/1

Y1 - 2020/3/1

N2 - Background: According to the 2010 S3 Guidelines, analgosedation is an option for ventilated patients in intensive care units (ICU). Therefore, adverse effects of volatile anesthetics can occur in areas outside of surgical medical fields. Objective: The aim is to inform ICU physicians about the clinical and legal challenges of a life-threatening pharmacogenetic reaction to inhalational anesthetics, malignant hyperthermia (MH). Discussion: Consequences of an MH crisis for doctors, patients, and relatives regarding patient rights legislation, as well as insurance and employment issues with respect to the German Genetic Diagnostics Act are discussed.

AB - Background: According to the 2010 S3 Guidelines, analgosedation is an option for ventilated patients in intensive care units (ICU). Therefore, adverse effects of volatile anesthetics can occur in areas outside of surgical medical fields. Objective: The aim is to inform ICU physicians about the clinical and legal challenges of a life-threatening pharmacogenetic reaction to inhalational anesthetics, malignant hyperthermia (MH). Discussion: Consequences of an MH crisis for doctors, patients, and relatives regarding patient rights legislation, as well as insurance and employment issues with respect to the German Genetic Diagnostics Act are discussed.

KW - Dantrolene

KW - General anesthesia

KW - German Genetic Diagnostics Act

KW - Malignant hyperthermia

KW - Pharmacogenetics

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Inhalative Analgosedierung auf der Intensivstation: Gefahr einer malignen Hyperthermie

Abstract

Schlagwörter

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