In-vivo cell and tissue monitoring with active implants

Johannes F. Clauss; Walter Wirths; Michael Roos; Budi Wohrle; Martin Brischwein; Bernhard Wolf

doi:10.1109/EMBC.2015.7320025

In-vivo cell and tissue monitoring with active implants

Johannes F. Clauss, Walter Wirths, Michael Roos, Budi Wohrle, Martin Brischwein, Bernhard Wolf

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Technische Universität München

Publikation: Beitrag in Buch/Bericht/Konferenzband › Konferenzbeitrag › Begutachtung

1 Zitat (Scopus)

Abstract

Active implant systems are becoming increasingly important in modern medicine. We describe the development of an implantable system for the monitoring of dissolved oxygen. Tissue oxygen saturation plays a leading role in many pathophysiological processes in the human body such as the growth of malignant tumors or the viability of transplanted organs. The implant allows monitoring the tissue oxygenation in vivo with a wireless interface to an external device. An improved self-calibration technique is described to minimize sensor drift with electrochemical sensors in vivo for a better long term stability of the implant system. The sensor was coated with a hydrogel membrane to avoid convection artifacts during calibration procedure.

Originalsprache	Englisch
Titel	2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
Herausgeber (Verlag)	Institute of Electrical and Electronics Engineers Inc.
Seiten	7087-7090
Seitenumfang	4
ISBN (elektronisch)	9781424492718
DOIs	https://doi.org/10.1109/EMBC.2015.7320025
Publikationsstatus	Veröffentlicht - 4 Nov. 2015
Veranstaltung	37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 - Milan, Italien Dauer: 25 Aug. 2015 → 29 Aug. 2015

Publikationsreihe

Name	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Band	2015-November
ISSN (Print)	1557-170X

Konferenz

Konferenz	37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
Land/Gebiet	Italien
Ort	Milan
Zeitraum	25/08/15 → 29/08/15

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Clauss, J. F., Wirths, W., Roos, M., Wohrle, B., Brischwein, M., & Wolf, B. (2015). In-vivo cell and tissue monitoring with active implants. in 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 (S. 7087-7090). Artikel 7320025 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; Band 2015-November). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2015.7320025

Clauss, Johannes F. ; Wirths, Walter ; Roos, Michael et al. / In-vivo cell and tissue monitoring with active implants. 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. Institute of Electrical and Electronics Engineers Inc., 2015. S. 7087-7090 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

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title = "In-vivo cell and tissue monitoring with active implants",

abstract = "Active implant systems are becoming increasingly important in modern medicine. We describe the development of an implantable system for the monitoring of dissolved oxygen. Tissue oxygen saturation plays a leading role in many pathophysiological processes in the human body such as the growth of malignant tumors or the viability of transplanted organs. The implant allows monitoring the tissue oxygenation in vivo with a wireless interface to an external device. An improved self-calibration technique is described to minimize sensor drift with electrochemical sensors in vivo for a better long term stability of the implant system. The sensor was coated with a hydrogel membrane to avoid convection artifacts during calibration procedure.",

author = "Clauss, {Johannes F.} and Walter Wirths and Michael Roos and Budi Wohrle and Martin Brischwein and Bernhard Wolf",

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Clauss, JF, Wirths, W, Roos, M, Wohrle, B, Brischwein, M & Wolf, B 2015, In-vivo cell and tissue monitoring with active implants. in 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015., 7320025, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, Bd. 2015-November, Institute of Electrical and Electronics Engineers Inc., S. 7087-7090, 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015, Milan, Italien, 25/08/15. https://doi.org/10.1109/EMBC.2015.7320025

In-vivo cell and tissue monitoring with active implants. / Clauss, Johannes F.; Wirths, Walter; Roos, Michael et al.
2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. Institute of Electrical and Electronics Engineers Inc., 2015. S. 7087-7090 7320025 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; Band 2015-November).

Publikation: Beitrag in Buch/Bericht/Konferenzband › Konferenzbeitrag › Begutachtung

TY - GEN

T1 - In-vivo cell and tissue monitoring with active implants

AU - Clauss, Johannes F.

AU - Wirths, Walter

AU - Roos, Michael

AU - Wohrle, Budi

AU - Brischwein, Martin

AU - Wolf, Bernhard

PY - 2015/11/4

Y1 - 2015/11/4

N2 - Active implant systems are becoming increasingly important in modern medicine. We describe the development of an implantable system for the monitoring of dissolved oxygen. Tissue oxygen saturation plays a leading role in many pathophysiological processes in the human body such as the growth of malignant tumors or the viability of transplanted organs. The implant allows monitoring the tissue oxygenation in vivo with a wireless interface to an external device. An improved self-calibration technique is described to minimize sensor drift with electrochemical sensors in vivo for a better long term stability of the implant system. The sensor was coated with a hydrogel membrane to avoid convection artifacts during calibration procedure.

AB - Active implant systems are becoming increasingly important in modern medicine. We describe the development of an implantable system for the monitoring of dissolved oxygen. Tissue oxygen saturation plays a leading role in many pathophysiological processes in the human body such as the growth of malignant tumors or the viability of transplanted organs. The implant allows monitoring the tissue oxygenation in vivo with a wireless interface to an external device. An improved self-calibration technique is described to minimize sensor drift with electrochemical sensors in vivo for a better long term stability of the implant system. The sensor was coated with a hydrogel membrane to avoid convection artifacts during calibration procedure.

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U2 - 10.1109/EMBC.2015.7320025

DO - 10.1109/EMBC.2015.7320025

M3 - Conference contribution

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AN - SCOPUS:84953231281

T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS

SP - 7087

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BT - 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015

PB - Institute of Electrical and Electronics Engineers Inc.

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ER -

Clauss JF, Wirths W, Roos M, Wohrle B, Brischwein M, Wolf B. In-vivo cell and tissue monitoring with active implants. in 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. Institute of Electrical and Electronics Engineers Inc. 2015. S. 7087-7090. 7320025. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). doi: 10.1109/EMBC.2015.7320025

In-vivo cell and tissue monitoring with active implants

Abstract

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