Improving the Use of CE in a Chromatographer's World

Since the introdduction of commercial capillary electrophoresis (CE) systems over 10 Years ago, separation mechanisms have become more clearly understood, and can now be modelled, simulated and thus controlled. However, it is important to think in terms of the ''CE world'' when troubleshooting CE methods rather than using conventional ''chromatography-mode thinking''. Raw electrophoretic data transformation into the effective mobility scale is a first step towards better reproducibility for both qualitative and quantitative analyses. Application examples are used to illustrate the power of this data transformation tool.