Four-dimensional optoacoustic temperature mapping in laser-induced thermotherapy

Francisco Javier Oyaga Landa, Xosé Luís Deán-Ben, Ronald Sroka, Daniel Razansky

Publikation: Beitrag in Buch/Bericht/KonferenzbandKonferenzbeitragBegutachtung

2 Zitate (Scopus)

Abstract

Photoablative laser therapy is in common use for selective destruction of malignant masses, vascular and brain abnormalities. Tissue ablation and coagulation are irreversible processes occurring shortly after crossing a certain thermal exposure threshold. As a result, accurate mapping of the temperature field is essential for optimizing the outcome of these clinical interventions. Here we demonstrate four-dimensional optoacoustic temperature mapping of the entire photoablated region. Accuracy of the method is investigated in tissue-mimicking phantom experiments. Deviations of the volumetric optoacoustic temperature readings provided at 40ms intervals remained below 10% for temperature elevations above 3°C, as validated by simultaneous thermocouple measurements. The excellent spatio-temporal resolution of the new temperature monitoring approach aims at improving safety and efficacy of laser-based photothermal procedures.

OriginalspracheEnglisch
TitelPhotons Plus Ultrasound
UntertitelImaging and Sensing 2018
Redakteure/-innenLihong V. Wang, Alexander A. Oraevsky
Herausgeber (Verlag)SPIE
ISBN (elektronisch)9781510614734
DOIs
PublikationsstatusVeröffentlicht - 2018
VeranstaltungPhotons Plus Ultrasound: Imaging and Sensing 2018 - San Francisco, USA/Vereinigte Staaten
Dauer: 28 Jan. 20181 Feb. 2018

Publikationsreihe

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Band10494
ISSN (Print)1605-7422

Konferenz

KonferenzPhotons Plus Ultrasound: Imaging and Sensing 2018
Land/GebietUSA/Vereinigte Staaten
OrtSan Francisco
Zeitraum28/01/181/02/18

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